Showing entry for Cocaine- and amphetamine-regulated transcript protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013640
Protein NameCocaine- and amphetamine-regulated transcript protein
Uniport IdQ16568
GeneCARTPT
Gene Id9607
DomainCART
Pfam PF06373  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000186 activation of MAPKK activity
Biological Process GO:0008343 adult feeding behavior
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0001678 cellular glucose homeostasis
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0032099 negative regulation of appetite
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0070093 negative regulation of glucagon secretion
Biological Process GO:0045671 negative regulation of osteoclast differentiation
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0045777 positive regulation of blood pressure
Biological Process GO:0032812 positive regulation of epinephrine secretion
Biological Process GO:0051971 positive regulation of transmission of nerve impulse
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0007165 signal transduction
Biological Process GO:0070253 somatostatin secretion
molecular function GO:0005184 neuropeptide hormone activity
cellular component GO:0005615 extracellular space
cellular component GO:0030141 secretory granule
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007095 BXGD000423 Carcinoid Tumor Neoplasms
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0009171 BXGD000587 Cocaine Abuse Chemically-Induced Disorders; Mental Disorders
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013473 BXGD000845 Eating Disorders Mental Disorders
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0021841 BXGD001519 Intestinal Neoplasms Digestive System Diseases; Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0026552 BXGD001906 Morphine Dependence Chemically-Induced Disorders; Mental Disorders
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028756 BXGD002083 Obesity, Morbid Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0035439 BXGD002551 Rheumatic Heart Disease Infections; Cardiovascular Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041671 BXGD002930 Attention Deficit Disorder Mental Disorders
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0154208 BXGD003707 Disorder of endocrine ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0206064 BXGD004150 Microvascular Angina Cardiovascular Diseases
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220656 BXGD004312 Malignant ascites Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
C0233401 BXGD004575 Psychiatric symptom
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0236664 BXGD004818 Alcohol-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0236736 BXGD004825 Cocaine-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0238013 BXGD004855 Invasive aspergillosis Infections
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242510 BXGD005173 Drug usage Chemically-Induced Disorders; Mental Disorders
C0243066 BXGD005213 Atresia
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280321 BXGD006739 Squamous cell carcinoma of the hypopharynx
C0334299 BXGD007027 Carcinoid tumor no ICD-O subtype Neoplasms
C0339002 BXGD007221 Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0376280 BXGD007983 Anxiety States, Neurotic Mental Disorders
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0458247 BXGD008904 Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0524662 BXGD009238 Opiate Addiction Chemically-Induced Disorders; Mental Disorders
C0600427 BXGD009706 Cocaine Dependence Chemically-Induced Disorders; Mental Disorders
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0730203 BXGD009937 Superficial femoral artery occlusion
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0746883 BXGD010153 Febrile Neutropenia Hemic and Lymphatic Diseases
C0751211 BXGD010350 Hyperalgesia, Primary Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751212 BXGD010351 Hyperalgesia, Secondary Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751213 BXGD010352 Tactile Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751229 BXGD010359 Hypersomnolence Nervous System Diseases; Mental Disorders
C0852949 BXGD010957 Arteriopathic disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948245 BXGD011520 Cytokine Release Syndrome Pathological Conditions, Signs and Symptoms; Chemically-Induced Disorders
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1279420 BXGD012122 Anxiety neurosis (finding) Mental Disorders
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1533217 BXGD013313 Methamphetamine dependence Chemically-Induced Disorders; Mental Disorders
C1632842 BXGD013481 Complicated appendicitis Digestive System Diseases; Infections
C1843013 BXGD014549 Alzheimer disease, familial, type 3 Nervous System Diseases; Mental Disorders
C1856184 BXGD015583 HEMIHYPERPLASIA, ISOLATED Pathological Conditions, Signs and Symptoms
C2004493 BXGD016875 Leukemia, B-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3275069 BXGD018658 Chronic Total Occlusion Vessel
C3714618 BXGD019417 Primary Hyperthyroidism Endocrine System Diseases
C4022947 BXGD021043 Decreased resting energy expenditure
C4528668 BXGD023176 Acute myeloid leukaemia refractory Neoplasms
C4703554 BXGD023657 Increased waist to hip ratio
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0014068 Amphetamine 135.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein