Showing entry for Grade III Childhood Astrocytoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023342
Disease NameGrade III Childhood Astrocytoma
Disease CUI IdC4551548
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15540 BXGT004178 Fatty acid-binding protein, brain 2173 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01574 BXGT005768 Interferon beta 3456 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P06756 BXGT006499 Integrin alpha-V 3685 reviewed
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P08574 BXGT006792 Cytochrome c1, heme protein, mitochondrial 1537 reviewed
P08648 BXGT006804 Integrin alpha-5 3678 reviewed
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P14415 BXGT008010 Sodium/potassium-transporting ATPase subunit beta-2 482 reviewed Transporter
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24593 BXGT008979 Insulin-like growth factor-binding protein 5 3488 reviewed Enzyme modulator
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P41222 BXGT010237 Prostaglandin-H2 D-isomerase 5730 reviewed Enzyme
P42261 BXGT010293 Glutamate receptor 1 2890 reviewed Ion channel
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P84243 BXGT012052 Histone H3.3 3021 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q7Z2E3 BXGT017246 Aprataxin 54840 reviewed Nucleic acid binding
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q96RJ3 BXGT019729 Tumor necrosis factor receptor superfamily member 13C 115650 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
Q9UGM3 BXGT025543 Deleted in malignant brain tumors 1 protein 1755 reviewed Enzyme
Q5BJF2 BXGT026107 Sigma intracellular receptor 2 27346 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease