protein

Showing entry for Deleted in malignant brain tumors 1 protein

General Target Information
BXGT Id	BXGT025543
Protein Name	Deleted in malignant brain tumors 1 protein
Uniport Id	Q9UGM3
Gene	DMBT1
Gene Id	1755
Domain	CUB; SRCR; Zona_pellucida
Pfam	PF00431 PF00530 PF00100
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
5. Organismal Systems	5.4 Digestive system	hsa04970	Salivary secretion

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
Biological Process	GO:0044267	cellular protein metabolic process
Biological Process	GO:0006952	defense response
Biological Process	GO:0050829	defense response to Gram-negative bacterium
Biological Process	GO:0050830	defense response to Gram-positive bacterium
Biological Process	GO:0051607	defense response to virus
Biological Process	GO:0042494	detection of bacterial lipoprotein
Biological Process	GO:0030855	epithelial cell differentiation
Biological Process	GO:0043152	induction of bacterial agglutination
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0007275	multicellular organism development
Biological Process	GO:0015031	protein transport
Biological Process	GO:0006898	receptor-mediated endocytosis
Biological Process	GO:0016032	viral process
molecular function	GO:0048306	calcium-dependent protein binding
molecular function	GO:0003677	DNA binding
molecular function	GO:0050840	extracellular matrix binding
molecular function	GO:1904399	heparan sulfate binding
molecular function	GO:0001530	lipopolysaccharide binding
molecular function	GO:0070891	lipoteichoic acid binding
molecular function	GO:0038187	pattern recognition receptor activity
molecular function	GO:0005044	scavenger receptor activity
molecular function	GO:0035375	zymogen binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0070062	extracellular exosome
cellular component	GO:0031012	extracellular matrix
cellular component	GO:0005576	extracellular region
cellular component	GO:0005615	extracellular space
cellular component	GO:0019898	extrinsic component of membrane
cellular component	GO:0030670	phagocytic vesicle membrane
cellular component	GO:0042589	zymogen granule membrane

Reactome

Pathway Id	Pathway Name
R-HSA-392499	Metabolism of proteins
R-HSA-5683826	Surfactant metabolism

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001206	BXGD000033	Acromegaly	Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0001418	BXGD000050	Adenocarcinoma	Neoplasms
C0001430	BXGD000054	Adenoma	Neoplasms
C0003504	BXGD000202	Aortic Valve Insufficiency	Cardiovascular Diseases
C0003615	BXGD000212	Appendicitis	Digestive System Diseases; Infections
C0004114	BXGD000255	Astrocytoma	Neoplasms
C0005684	BXGD000319	Malignant neoplasm of urinary bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695	BXGD000323	Bladder Neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006118	BXGD000372	Brain Neoplasms	Neoplasms; Nervous System Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007097	BXGD000424	Carcinoma	Neoplasms
C0007102	BXGD000425	Malignant tumor of colon	Digestive System Diseases; Neoplasms
C0007114	BXGD000431	Malignant neoplasm of skin	Neoplasms; Skin and Connective Tissue Diseases
C0007131	BXGD000441	Non-Small Cell Lung Carcinoma	Neoplasms; Respiratory Tract Diseases
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0007222	BXGD000454	Cardiovascular Diseases	Cardiovascular Diseases
C0008312	BXGD000527	Primary biliary cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008626	BXGD000559	Congenital chromosomal disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009319	BXGD000596	Colitis	Digestive System Diseases
C0009324	BXGD000597	Ulcerative Colitis	Digestive System Diseases
C0009375	BXGD000602	Colonic Neoplasms	Digestive System Diseases; Neoplasms
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0010068	BXGD000648	Coronary heart disease	Cardiovascular Diseases
C0010278	BXGD000660	Craniosynostosis	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010346	BXGD000664	Crohn Disease	Digestive System Diseases
C0011860	BXGD000755	Diabetes Mellitus, Non-Insulin-Dependent	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017152	BXGD001096	Gastritis	Digestive System Diseases
C0017154	BXGD001097	Gastritis, Atrophic	Digestive System Diseases
C0017636	BXGD001131	Glioblastoma	Neoplasms
C0017638	BXGD001132	Glioma	Neoplasms
C0018553	BXGD001203	Hamartoma Syndrome, Multiple	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0019158	BXGD001293	Hepatitis	Digestive System Diseases
C0019159	BXGD001294	Hepatitis A	Digestive System Diseases; Infections
C0019163	BXGD001295	Hepatitis B	Digestive System Diseases; Infections
C0020625	BXGD001451	Hyponatremia	Nutritional and Metabolic Diseases
C0021368	BXGD001502	Inflammation	Pathological Conditions, Signs and Symptoms
C0021390	BXGD001503	Inflammatory Bowel Diseases	Digestive System Diseases
C0022104	BXGD001529	Irritable Bowel Syndrome	Digestive System Diseases
C0023418	BXGD001642	leukemia	Neoplasms
C0023890	BXGD001713	Liver Cirrhosis	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895	BXGD001717	Liver diseases	Digestive System Diseases
C0023976	BXGD001724	Long QT Syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0024121	BXGD001735	Lung Neoplasms	Neoplasms; Respiratory Tract Diseases
C0024141	BXGD001740	Lupus Erythematosus, Systemic	Skin and Connective Tissue Diseases; Immune System Diseases
C0025048	BXGD001823	Meconium Aspiration Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Respiratory Tract Diseases
C0025149	BXGD001826	Medulloblastoma	Neoplasms
C0025202	BXGD001832	melanoma	Neoplasms
C0027430	BXGD001988	Nasal Polyps	Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027819	BXGD002043	Neuroblastoma	Neoplasms
C0027960	BXGD002062	Nevus	Neoplasms
C0027962	BXGD002064	Melanocytic nevus	Neoplasms
C0028433	BXGD002078	Nose Neoplasms	Neoplasms; Musculoskeletal Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0028945	BXGD002099	oligodendroglioma	Neoplasms
C0031090	BXGD002280	Periodontal Diseases	Stomatognathic Diseases
C0031511	BXGD002304	Pheochromocytoma	Neoplasms
C0032580	BXGD002362	Adenomatous Polyposis Coli	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033036	BXGD002389	Atrial Premature Complexes	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0034050	BXGD002452	Pulmonary Alveolar Proteinosis	Respiratory Tract Diseases
C0038644	BXGD002776	Sudden infant death syndrome	Pathological Conditions, Signs and Symptoms
C0149516	BXGD003324	Chronic sinusitis	Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0149925	BXGD003387	Small cell carcinoma of lung	Neoplasms; Respiratory Tract Diseases
C0153633	BXGD003674	Malignant neoplasm of brain	Neoplasms; Nervous System Diseases
C0153690	BXGD003684	Secondary malignant neoplasm of bone	Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0175702	BXGD004008	Williams Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0178874	BXGD004037	Tumor Progression	Pathological Conditions, Signs and Symptoms
C0206663	BXGD004225	Neuroectodermal Tumor, Primitive	Neoplasms
C0206695	BXGD004246	Carcinoma, Neuroendocrine	Neoplasms
C0206698	BXGD004248	Cholangiocarcinoma	Neoplasms
C0206716	BXGD004262	Ganglioglioma	Neoplasms
C0206754	BXGD004289	Neuroendocrine Tumors	Neoplasms
C0231918	BXGD004529	Nose symptoms
C0235782	BXGD004769	Gallbladder Carcinoma	Digestive System Diseases; Neoplasms
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0242383	BXGD005160	Age related macular degeneration	Eye Diseases
C0265493	BXGD005538	Cat eye syndrome	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0278510	BXGD006526	Childhood Medulloblastoma	Neoplasms
C0278876	BXGD006607	Adult Medulloblastoma	Neoplasms
C0278878	BXGD006609	Adult Glioblastoma	Neoplasms
C0279671	BXGD006677	Cervical Squamous Cell Carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0279680	BXGD006680	Transitional cell carcinoma of bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474	BXGD006748	Childhood Glioblastoma	Neoplasms
C0280483	BXGD006750	Adult Anaplastic Astrocytoma	Neoplasms
C0280785	BXGD006760	Diffuse Astrocytoma	Neoplasms
C0334037	BXGD006980	Intestinal metaplasia
C0334579	BXGD007120	Anaplastic astrocytoma	Neoplasms
C0345905	BXGD007746	Intrahepatic Cholangiocarcinoma	Neoplasms
C0376358	BXGD007992	Malignant neoplasm of prostate	Neoplasms; Male Urogenital Diseases
C0496899	BXGD009046	Benign neoplasm of brain, unspecified	Neoplasms; Nervous System Diseases
C0520463	BXGD009085	Chronic active hepatitis	Digestive System Diseases
C0521158	BXGD009130	Recurrent tumor
C0546837	BXGD009343	Malignant neoplasm of esophagus	Digestive System Diseases; Neoplasms
C0549473	BXGD009384	Thyroid carcinoma	Neoplasms; Endocrine System Diseases
C0555198	BXGD009432	Malignant Glioma	Neoplasms
C0574143	BXGD009503	Liver calculus
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139	BXGD009695	Prostate carcinoma	Neoplasms; Male Urogenital Diseases
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0684249	BXGD009790	Carcinoma of lung	Neoplasms; Respiratory Tract Diseases
C0684337	BXGD009796	Ewings sarcoma-primitive neuroectodermal tumor (PNET)	Neoplasms
C0685938	BXGD009829	Malignant neoplasm of gastrointestinal tract	Digestive System Diseases; Neoplasms
C0699885	BXGD009869	Carcinoma of bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095	BXGD009875	Central neuroblastoma	Neoplasms; Nervous System Diseases
C0729777	BXGD009934	Corneal Infection	Infections; Eye Diseases
C0750952	BXGD010263	Biliary Tract Cancer	Digestive System Diseases; Neoplasms
C0751396	BXGD010425	Well Differentiated Oligodendroglioma	Neoplasms
C0850666	BXGD010901	Infection caused by Helicobacter pylori	Infections
C0940937	BXGD011490	precancerous lesions
C1258085	BXGD011822	Barrett Epithelium	Digestive System Diseases; Neoplasms
C1269955	BXGD012005	Tumor Cell Invasion
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1306460	BXGD012362	Primary malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C1332977	BXGD012569	Childhood Leukemia	Neoplasms
C1336538	BXGD012849	Supratentorial Embryonal Tumor, Not Otherwise Specified	Neoplasms; Nervous System Diseases
C1456781	BXGD013123	Benign melanocytic nevus	Neoplasms
C1458155	BXGD013136	Mammary Neoplasms	Neoplasms; Skin and Connective Tissue Diseases
C1608408	BXGD013434	Malignant transformation
C1621958	BXGD013468	Glioblastoma Multiforme	Neoplasms
C1623038	BXGD013475	Cirrhosis	Pathological Conditions, Signs and Symptoms
C1879344	BXGD016574	Biliary papillomatosis	Digestive System Diseases; Neoplasms
C2062441	BXGD016897	Influenza A
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2607914	BXGD017148	Allergic rhinitis (disorder)	Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C3551052	BXGD019144	Night blindness, stationary
C3805278	BXGD019474	Extrahepatic Cholangiocarcinoma	Neoplasms
C3826128	BXGD019713	Infection in children
C4086152	BXGD022123	Childhood Astrocytoma	Neoplasms
C4086165	BXGD022126	Childhood Neuroblastoma	Neoplasms
C4284013	BXGD022428	Primary cholangiocarcinoma of intrahepatic biliary tract	Neoplasms
C4511687	BXGD023010	Pancreatic Intraductal Papillary Mucinous Neoplasm	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C4551548	BXGD023342	Grade III Childhood Astrocytoma	Neoplasms
C4552766	BXGD023523	Miscarriage	Female Urogenital Diseases and Pregnancy Complications
C4722085	BXGD023788	Malignant neoplasm of colon and/or rectum
C4728046	BXGD023884	Diabetic wound

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09
BXGC0002588	Magnesium		24.31
BXGC0003705	Chloride		35.45

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}