Showing entry for Depression, Bipolar


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000316
Disease NameDepression, Bipolar
Disease CUI IdC0005587
MeSH Codes F03  
Disease Class NameMental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:150  
Disease Ontology Class Namedisease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14594 BXGT004073 Neurocan core protein 1463 reviewed Extracellular structure
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O94759 BXGT005327 Transient receptor potential cation channel subfamily M member 2 7226 reviewed Ion channel
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P19404 BXGT008477 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial 4729 reviewed
P19827 BXGT008523 Inter-alpha-trypsin inhibitor heavy chain H1 3697 reviewed Enzyme modulator
P20472 BXGT008578 Parvalbumin alpha 5816 reviewed Calcium-binding protein
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21918 BXGT008708 D(1B) dopamine receptor 1816 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P49840 BXGT010749 Glycogen synthase kinase-3 alpha 2931 reviewed Kinase
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P78362 BXGT011839 SRSF protein kinase 2 6733 reviewed Kinase
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q07343 BXGT012926 cAMP-specific 3',5'-cyclic phosphodiesterase 4B 5142 reviewed
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13043 BXGT013307 Serine/threonine-protein kinase 4 6789 reviewed Kinase
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q15349 BXGT013558 Ribosomal protein S6 kinase alpha-2 6196 reviewed Kinase
Q16099 BXGT013620 Glutamate receptor ionotropic, kainate 4 2900 reviewed Ion channel
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor 4915 reviewed Kinase
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96CW9 BXGT019634 Netrin-G2 84628 reviewed Enzyme modulator
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q9UQL6 BXGT021813 Histone deacetylase 5 10014 reviewed Epigenetic regulator
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha 815 reviewed Kinase
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y2I2 BXGT022236 Netrin-G1 22854 reviewed Enzyme modulator
F1T0I5 BXGT022675 Arylalkylamine N-acetyltransferase (Serotonin N-acetyltransferase) 15 unreviewed
Q9H694 BXGT024116 Protein bicaudal C homolog 1 80114 reviewed Transporter
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease