Showing entry for Serum total cholesterol measurement


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013081
Disease NameSerum total cholesterol measurement
Disease CUI IdC1445957
MeSH Codes   
Disease Class Name
Semantic TypeLaboratory Procedure
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00187 BXGT003890 Mannan-binding lectin serine protease 2 10747 reviewed Enzyme
O00341 BXGT003913 Excitatory amino acid transporter 5 6512 reviewed Transporter
O14594 BXGT004073 Neurocan core protein 1463 reviewed Extracellular structure
O14924 BXGT004111 Regulator of G-protein signaling 12 6002 reviewed
O15111 BXGT004126 Inhibitor of nuclear factor kappa-B kinase subunit alpha 1147 reviewed Kinase
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O43175 BXGT004575 D-3-phosphoglycerate dehydrogenase 26227 reviewed Enzyme
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60494 BXGT004879 Cubilin 8029 reviewed
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 54600 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 7398 reviewed Enzyme
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O94888 BXGT005338 UBX domain-containing protein 7 26043 reviewed
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95622 BXGT005386 Adenylate cyclase type 5 111 reviewed
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00739 BXGT005633 Haptoglobin-related protein 3250 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01730 BXGT005781 T-cell surface glycoprotein CD4 920 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01903 BXGT005814 HLA class II histocompatibility antigen, DR alpha chain 3122 reviewed Immune response
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02675 BXGT005916 Fibrinogen beta chain 2244 reviewed Signaling
P02749 BXGT005941 Beta-2-glycoprotein 1 350 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03951 BXGT006117 Coagulation factor XI 2160 reviewed Enzyme
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04180 BXGT006164 Phosphatidylcholine-sterol acyltransferase 3931 reviewed Enzyme
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P06681 BXGT006468 Complement C2 717 reviewed
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07306 BXGT006595 Asialoglycoprotein receptor 1 432 reviewed Receptor
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P08709 BXGT006818 Coagulation factor VII 2155 reviewed Enzyme
P09238 BXGT006875 Stromelysin-2 4319 reviewed Enzyme
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10600 BXGT007584 Transforming growth factor beta-3 proprotein 7043 reviewed Signaling
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P11717 BXGT007740 Cation-independent mannose-6-phosphate receptor 3482 reviewed Receptor
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P15382 BXGT008116 Potassium voltage-gated channel subfamily E member 1 3753 reviewed Ion channel
P16070 BXGT008186 CD44 antigen 960 reviewed
P16109 BXGT008194 P-selectin 6403 reviewed
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P18206 BXGT008389 Vinculin 7414 reviewed
P19174 BXGT008467 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5335 reviewed Enzyme
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 54578 reviewed
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 54657 reviewed
P22680 BXGT008794 Cholesterol 7-alpha-monooxygenase 1581 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23786 BXGT008906 Carnitine O-palmitoyltransferase 2, mitochondrial 1376 reviewed Enzyme
P24723 BXGT008989 Protein kinase C eta type 5583 reviewed Kinase
P24855 BXGT008998 Deoxyribonuclease-1 1773 reviewed
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27540 BXGT009190 Aryl hydrocarbon receptor nuclear translocator 405 reviewed Transcription factor
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 54659 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P41161 BXGT010229 ETS translocation variant 5 2119 reviewed Transcription factor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P41240 BXGT010242 Tyrosine-protein kinase CSK 1445 reviewed Kinase
P41440 BXGT010261 Folate transporter 1 6573 reviewed Transporter
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42685 BXGT010332 Tyrosine-protein kinase FRK 2444 reviewed Kinase
P47712 BXGT010577 Cytosolic phospholipase A2 5321 reviewed Enzyme
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P50993 BXGT010826 Sodium/potassium-transporting ATPase subunit alpha-2 477 reviewed Transporter
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52732 BXGT010948 Kinesin-like protein KIF11 3832 reviewed Cellular structure
P54760 BXGT011075 Ephrin type-B receptor 4 2050 reviewed Kinase
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P55899 BXGT011131 IgG receptor FcRn large subunit p51 2217 reviewed
P56199 BXGT011150 Integrin alpha-1 3672 reviewed
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P62750 BXGT011453 60S ribosomal protein L23a 6147 reviewed Nucleic acid binding
P62753 BXGT011454 40S ribosomal protein S6 6194 reviewed Nucleic acid binding
P62942 BXGT011474 Peptidyl-prolyl cis-trans isomerase FKBP1A 2280 reviewed Enzyme
P68036 BXGT011572 Ubiquitin-conjugating enzyme E2 L3 7332 reviewed Enzyme
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial 1723 reviewed Enzyme
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q04759 BXGT012781 Protein kinase C theta type 5588 reviewed Kinase
Q07343 BXGT012926 cAMP-specific 3',5'-cyclic phosphodiesterase 4B 5142 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q12931 BXGT013282 Heat shock protein 75 kDa, mitochondrial 10131 reviewed Chaperone
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14114 BXGT013441 Low-density lipoprotein receptor-related protein 8 7804 reviewed
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14397 BXGT013467 Glucokinase regulatory protein 2646 reviewed
Q14653 BXGT013494 Interferon regulatory factor 3 3661 reviewed Transcription factor
Q14974 BXGT013516 Importin subunit beta-1 3837 reviewed Transporter
Q15036 BXGT013526 Sorting nexin-17 9784 reviewed
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15369 BXGT013560 Elongin-C 6921 reviewed Enzyme modulator
Q16549 BXGT013637 Proprotein convertase subtilisin/kexin type 7 9159 reviewed
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q5T280 BXGT015845 Putative methyltransferase C9orf114 51490 reviewed
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q68D10 BXGT016187 Protein SPT2 homolog 144108 reviewed Nucleic acid binding
Q6GTX8 BXGT016315 Leukocyte-associated immunoglobulin-like receptor 1 3903 reviewed Receptor
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q86X55 BXGT017627 Histone-arginine methyltransferase CARM1 10498 reviewed Epigenetic regulator
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EY8 BXGT019655 Corrinoid adenosyltransferase 326625 reviewed Enzyme
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 10919 reviewed Epigenetic regulator
Q96L34 BXGT019689 MAP/microtubule affinity-regulating kinase 4 57787 reviewed Kinase
Q99523 BXGT019929 Sortilin 6272 reviewed Transporter
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99685 BXGT019948 Monoglyceride lipase 11343 reviewed Enzyme
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 54577 reviewed
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 54575 reviewed
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 54576 reviewed
Q9NSI6 BXGT021208 Bromodomain and WD repeat-containing protein 1 54014 reviewed
Q9NX01 BXGT021241 Thioredoxin-like protein 4B 54957 reviewed
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UBT6 BXGT021664 DNA polymerase kappa 51426 reviewed
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 51422 reviewed Enzyme modulator
Q9UHC9 BXGT021696 NPC1-like intracellular cholesterol transporter 1 29881 reviewed Transporter
Q9UK55 BXGT021738 Protein Z-dependent protease inhibitor 51156 reviewed Enzyme modulator
Q9UKL6 BXGT021746 Phosphatidylcholine transfer protein 58488 reviewed
Q9ULV8 BXGT021765 E3 ubiquitin-protein ligase CBL-C 23624 reviewed Enzyme
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
Q9Y2K2 BXGT022238 Serine/threonine-protein kinase SIK3 23387 reviewed Kinase
Q9Y5P4 BXGT022298 Collagen type IV alpha-3-binding protein 10087 reviewed Transporter
Q9Y5X9 BXGT022307 Endothelial lipase 9388 reviewed Enzyme
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 1456 reviewed Kinase
Q01995 BXGT022678 Transgelin 6876 reviewed Cellular structure
Q5JP69 BXGT022691 C3/C5 convertase 717 unreviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q63ZY3 BXGT023544 KN motif and ankyrin repeat domain-containing protein 2 25959 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
P61916 BXGT025881 NPC intracellular cholesterol transporter 2 10577 reviewed
Q9BQ69 BXGT026098 ADP-ribose glycohydrolase MACROD1 28992 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease