Showing entry for Retinaldehyde-binding protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007786
Protein NameRetinaldehyde-binding protein 1
Uniport IdP12271
GeneRLBP1
Gene Id6017
DomainCRAL_TRIO; CRAL_TRIO_N
Pfam PF00650   PF03765  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050896 response to stimulus
Biological Process GO:0001523 retinoid metabolic process
Biological Process GO:0007601 visual perception
Biological Process GO:0006776 vitamin A metabolic process
molecular function GO:0005502 11-cis retinal binding
molecular function GO:1902936 phosphatidylinositol bisphosphate binding
molecular function GO:0019841 retinol binding
cellular component GO:0044297 cell body
cellular component GO:0005813 centrosome
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-2187335 The retinoid cycle in cones (daylight vision)
R-HSA-2187335 The retinoid cycle in cones (daylight vision)
R-HSA-2187338 Visual phototransduction
R-HSA-2187338 Visual phototransduction
R-HSA-2453864 Retinoid cycle disease events
R-HSA-2453902 The canonical retinoid cycle in rods (twilight vision)
R-HSA-2474795 Diseases associated with visual transduction
R-HSA-372790 Signaling by GPCR
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-418594 G alpha (i) signalling events
R-HSA-9675143 Diseases of the neuronal system
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009398 BXGD000604 Color vision defect Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0015398 BXGD000984 Eye Diseases, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0018777 BXGD001217 Conductive hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0022578 BXGD001557 Keratoconus Eye Diseases
C0024440 BXGD001774 Macular Edema, Cystoid Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028077 BXGD002069 Nyctalopia Eye Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029089 BXGD002107 Ophthalmoplegia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035333 BXGD002538 Retinitis Eye Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036454 BXGD002616 Scotoma Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0042164 BXGD002965 Uveitis Eye Diseases
C0085636 BXGD003218 Photophobia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152191 BXGD003556 Scotoma, Central Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0205710 BXGD004112 Alpers Syndrome (disorder) Immune System Diseases; Nervous System Diseases
C0239119 BXGD004963 Lenticonus
C0241688 BXGD005107 Peripheral visual field loss
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0266435 BXGD005668 Congenital hypoplasia of penis Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0311338 BXGD006878 Fundus Albipunctatus Eye Diseases
C0339526 BXGD007259 Autosomal recessive retinitis pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0423420 BXGD008483 Absent foveal reflex
C0423421 BXGD008484 Atrophic macular change
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0476397 BXGD008991 Electroretinogram abnormal
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0730290 BXGD009946 Cone Dystrophy Eye Diseases
C0854723 BXGD011026 Retinal Dystrophies Eye Diseases
C1288283 BXGD012175 Atrophoderma maculatum Skin and Connective Tissue Diseases
C1405854 BXGD013028 Retinitis punctata albescens (disorder) Eye Diseases
C1568247 BXGD013418 Usher Syndrome, Type I Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1839364 BXGD014371 Progressive visual loss
C1840077 BXGD014434 Anteverted nostril
C1843815 BXGD014608 Newfoundland Rod-Cone Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1843816 BXGD014609 Bothnia Retinal Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1849367 BXGD015046 Nasal bridge wide
C1857644 BXGD015728 Retinal pigment epithelial mottling
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1865866 BXGD016345 Congenital sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2751492 BXGD017718 AMYLOIDOSIS, HEREDITARY, TRANSTHYRETIN-RELATED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C2931205 BXGD017977 Usher syndrome, type 1A Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C3151111 BXGD018397 Abnormal light- and dark-adapted electroretinogram
C3278975 BXGD018749 Attenuation of retinal blood vessels
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4021786 BXGD020779 Atypical scarring of skin Pathological Conditions, Signs and Symptoms
C4024760 BXGD021408 Progressive visual field defects
C4024818 BXGD021428 Progressive night blindness Eye Diseases
C4072991 BXGD022029 Yellow/white lesions of the retina
C4551633 BXGD023378 Pigmentary retinal dystrophy Eye Diseases
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4703439 BXGD023647 Abnormality of fundus pigmentation
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000696 Tartaric acid 150.09
BXGC0037666 Retinal 284.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein