adisease

Showing entry for Ophthalmoplegia

General Disease Information
BXGD Id	BXGD002107
Disease Name	Ophthalmoplegia
Disease CUI Id	C0029089
MeSH Codes	C23 C11 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00217	BXGT003898	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	4728	reviewed	Enzyme
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00483	BXGT003930	Cytochrome c oxidase subunit NDUFA4	4697	reviewed	Enzyme
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15146	BXGT004131	Muscle, skeletal receptor tyrosine-protein kinase	4593	reviewed	Kinase
O43181	BXGT004576	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	4724	reviewed
O43678	BXGT004613	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	4695	reviewed	Enzyme
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
O75306	BXGT005108	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	4720	reviewed	Enzyme
O75489	BXGT005131	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	4722	reviewed
O75643	BXGT005142	U5 small nuclear ribonucleoprotein 200 kDa helicase	23020	reviewed
O95169	BXGT005356	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	4714	reviewed	Enzyme
O95237	BXGT005361	Lecithin retinol acyltransferase	9227	reviewed
O95299	BXGT005372	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	4705	reviewed	Enzyme
P00156	BXGT005469	Cytochrome b	4519	reviewed
P00846	BXGT005674	ATP synthase subunit a	4508	reviewed	Transporter
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P02708	BXGT005927	Acetylcholine receptor subunit alpha	1134	reviewed	Ion channel
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P08100	BXGT006725	Rhodopsin	6010	reviewed	G-protein coupled receptor
P08559	BXGT006788	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	5160	reviewed
P10745	BXGT007608	Retinol-binding protein 3	5949	reviewed
P11230	BXGT007677	Acetylcholine receptor subunit beta	1140	reviewed	Ion channel
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12271	BXGT007786	Retinaldehyde-binding protein 1	6017	reviewed	Transporter
P16499	BXGT008238	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	5145	reviewed
P19404	BXGT008477	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	4729	reviewed
P19971	BXGT008537	Thymidine phosphorylase	1890	reviewed	Enzyme
P20794	BXGT008600	Serine/threonine-protein kinase MAK	4117	reviewed	Kinase
P20839	BXGT008608	Inosine-5'-monophosphate dehydrogenase 1	3614	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P22748	BXGT008802	Carbonic anhydrase 4	762	reviewed
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P28331	BXGT009252	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	4719	reviewed	Enzyme
P29973	BXGT009389	cGMP-gated cation channel alpha-1	1259	reviewed	Ion channel
P30084	BXGT009398	Enoyl-CoA hydratase, mitochondrial	1892	reviewed	Enzyme
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P35052	BXGT009788	Glypican-1	2817	reviewed
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35913	BXGT009879	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	5158	reviewed
P43155	BXGT010363	Carnitine O-acetyltransferase	1384	reviewed	Enzyme
P49821	BXGT010748	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	4723	reviewed
P50213	BXGT010779	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	3419	reviewed	Enzyme
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P82279	BXGT011972	Protein crumbs homolog 1	23418	reviewed
Q04844	BXGT012789	Acetylcholine receptor subunit epsilon	1145	reviewed	Ion channel
Q07001	BXGT012907	Acetylcholine receptor subunit delta	1144	reviewed	Ion channel
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q16795	BXGT013671	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	4704	reviewed	Enzyme
Q5JPH6	BXGT015456	Probable glutamate--tRNA ligase, mitochondrial	124454	reviewed	Enzyme
Q6P2Q9	BXGT016446	Pre-mRNA-processing-splicing factor 8	10594	reviewed	Nucleic acid binding
Q8N183	BXGT018497	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2	91942	reviewed
Q8WWY3	BXGT019006	U4/U6 small nuclear ribonucleoprotein Prp31	26121	reviewed	Nucleic acid binding
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q96NR8	BXGT019701	Retinol dehydrogenase 12	145226	reviewed	Enzyme
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BPX6	BXGT020104	Calcium uptake protein 1, mitochondrial	10367	reviewed	Calcium-binding protein
Q9BQP7	BXGT020114	Mitochondrial genome maintenance exonuclease 1	92667	reviewed
Q9BU61	BXGT020131	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3	25915	reviewed
Q9GZV3	BXGT020427	High affinity choline transporter 1	60482	reviewed	Transporter
Q9H0F7	BXGT020435	ADP-ribosylation factor-like protein 6	84100	reviewed
Q9NX46	BXGT021243	ADP-ribose glycohydrolase ARH3	54936	reviewed
Q9NYL2	BXGT021259	Mitogen-activated protein kinase kinase kinase 20	51776	reviewed	Kinase
Q9P0J0	BXGT021287	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	51079	reviewed	Enzyme
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9UI09	BXGT021710	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	55967	reviewed
Q9UK17	BXGT021735	Potassium voltage-gated channel subfamily D member 3	3752	reviewed	Ion channel
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9Y234	BXGT022211	Lipoyltransferase 1, mitochondrial	51601	reviewed	Enzyme
Q9Y4D7	BXGT022275	Plexin-D1	23129	reviewed
Q9Y5X4	BXGT022306	Photoreceptor-specific nuclear receptor	10002	reviewed	Nuclear receptor
P35240	BXGT022927	Merlin	4771	reviewed
Q7Z4S6	BXGT023001	Kinesin-like protein KIF21A	55605	reviewed	Cellular structure
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
O43837	BXGT024635	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	3420	reviewed	Enzyme
Q9UNE7	BXGT025000	E3 ubiquitin-protein ligase CHIP	10273	reviewed
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
O43172	BXGT026158	U4/U6 small nuclear ribonucleoprotein Prp4	9128	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}