Showing entry for Keratoderma, Palmoplantar


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023384
Disease NameKeratoderma, Palmoplantar
Disease CUI IdC4551675
MeSH Codes C16   C17  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0001574  
Human Phenotype Ontology TermAbnormality of the integument
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O75112 BXGT005099 LIM domain-binding protein 3 11155 reviewed Cellular structure
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02538 BXGT005888 Keratin, type II cytoskeletal 6A 3853 reviewed
P03952 BXGT006118 Plasma kallikrein 3818 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P08779 BXGT006824 Keratin, type I cytoskeletal 16 3868 reviewed
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P12955 BXGT007865 Xaa-Pro dipeptidase 5184 reviewed Enzyme
P13631 BXGT007929 Retinoic acid receptor gamma 5916 reviewed Nuclear receptor
P13645 BXGT007936 Keratin, type I cytoskeletal 10 3858 reviewed
P13647 BXGT007937 Keratin, type II cytoskeletal 5 3852 reviewed
P14923 BXGT008069 Junction plakoglobin 3728 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3248 reviewed
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P16144 BXGT008200 Integrin beta-4 3691 reviewed Receptor
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17735 BXGT008335 Tyrosine aminotransferase 6898 reviewed
P18206 BXGT008389 Vinculin 7414 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P20810 BXGT008602 Calpastatin 831 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P22830 BXGT008809 Ferrochelatase, mitochondrial 2235 reviewed Enzyme
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35527 BXGT009843 Keratin, type I cytoskeletal 9 3857 reviewed
P35908 BXGT009878 Keratin, type II cytoskeletal 2 epidermal 3849 reviewed
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 5605 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P45379 BXGT010459 Troponin T, cardiac muscle 7139 reviewed Cellular structure
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P63316 BXGT011517 Troponin C, slow skeletal and cardiac muscles 7134 reviewed Calcium-binding protein
Q02487 BXGT012656 Desmocollin-2 1824 reviewed Cell adhesion
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q14126 BXGT013446 Desmoglein-2 1829 reviewed Cell adhesion
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14524 BXGT013478 Sodium channel protein type 5 subunit alpha 6331 reviewed Ion channel
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q2MKA7 BXGT014140 R-spondin-1 284654 reviewed
Q8NET8 BXGT018557 Transient receptor potential cation channel subfamily V member 3 162514 reviewed Ion channel
Q8TD43 BXGT018806 Transient receptor potential cation channel subfamily M member 4 54795 reviewed Ion channel
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92959 BXGT019400 Solute carrier organic anion transporter family member 2A1 6578 reviewed Transporter
Q9BQ65 BXGT020107 U6 snRNA phosphodiesterase 79650 reviewed
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
Q63ZY3 BXGT023544 KN motif and ankyrin repeat domain-containing protein 2 25959 reviewed
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease