Showing entry for Cyclin-dependent-like kinase 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012692
Protein NameCyclin-dependent-like kinase 5
Uniport IdQ03114
GeneCdk5
Gene Id140908
DomainPkinase
Pfam PF00069  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0008306 associative learning
Biological Process GO:0048675 axon extension
Biological Process GO:0007409 axonogenesis
Biological Process GO:0048148 behavioral response to cocaine
Biological Process GO:0070509 calcium ion import
Biological Process GO:0051301 cell division
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0016477 cell migration
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:0007417 central nervous system development
Biological Process GO:0021954 central nervous system neuron development
Biological Process GO:0021695 cerebellar cortex development
Biological Process GO:0021697 cerebellar cortex formation
Biological Process GO:0021549 cerebellum development
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0022038 corpus callosum development
Biological Process GO:0030866 cortical actin cytoskeleton organization
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0006887 exocytosis
Biological Process GO:0030900 forebrain development
Biological Process GO:0021766 hippocampus development
Biological Process GO:0016572 histone phosphorylation
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0021819 layer formation in cerebral cortex
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0008045 motor neuron axon guidance
Biological Process GO:0030517 negative regulation of axon extension
Biological Process GO:0045786 negative regulation of cell cycle
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:0046826 negative regulation of protein export from nucleus
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0045861 negative regulation of proteolysis
Biological Process GO:0031914 negative regulation of synaptic plasticity
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0001764 neuron migration
Biological Process GO:0031175 neuron projection development
Biological Process GO:0048812 neuron projection morphogenesis
Biological Process GO:0006913 nucleocytoplasmic transport
Biological Process GO:0048709 oligodendrocyte differentiation
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0016310 phosphorylation
Biological Process GO:0045956 positive regulation of calcium ion-dependent exocytosis
Biological Process GO:0034352 positive regulation of glial cell apoptotic process
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0099533 positive regulation of presynaptic cytosolic calcium concentration
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0045860 positive regulation of protein kinase activity
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:1901387 positive regulation of voltage-gated calcium channel activity
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0035418 protein localization to synapse
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0032801 receptor catabolic process
Biological Process GO:0043113 receptor clustering
Biological Process GO:0045055 regulated exocytosis
Biological Process GO:0030334 regulation of cell migration
Biological Process GO:0061001 regulation of dendritic spine morphogenesis
Biological Process GO:0060078 regulation of postsynaptic membrane potential
Biological Process GO:1903076 regulation of protein localization to plasma membrane
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
Biological Process GO:0042220 response to cocaine
Biological Process GO:0009611 response to wounding
Biological Process GO:0048511 rhythmic process
Biological Process GO:0014044 Schwann cell development
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0042501 serine phosphorylation of STAT protein
Biological Process GO:0007519 skeletal muscle tissue development
Biological Process GO:0007416 synapse assembly
Biological Process GO:0001963 synaptic transmission, dopaminergic
Biological Process GO:0035249 synaptic transmission, glutamatergic
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0048489 synaptic vesicle transport
Biological Process GO:0021537 telencephalon development
Biological Process GO:0008542 visual learning
molecular function GO:0030549 acetylcholine receptor activator activity
molecular function GO:0005524 ATP binding
molecular function GO:0004693 cyclin-dependent protein serine/threonine kinase activity
molecular function GO:0008092 cytoskeletal protein binding
molecular function GO:0046875 ephrin receptor binding
molecular function GO:0005176 ErbB-2 class receptor binding
molecular function GO:0043125 ErbB-3 class receptor binding
molecular function GO:0051879 Hsp90 protein binding
molecular function GO:0016301 kinase activity
molecular function GO:0002039 p53 binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0050321 tau-protein kinase activity
molecular function GO:0099635 voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
cellular component GO:0030424 axon
cellular component GO:0030054 cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0030175 filopodium
cellular component GO:0030426 growth cone
cellular component GO:0030027 lamellipodium
cellular component GO:0016020 membrane
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098793 presynapse
cellular component GO:0016533 protein kinase 5 complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000142 6-Hydroxykaempferol 302.24
BXGC0000340 Kaempferol 286.24
BXGC0000964 6-Methylscutellarein 300.26
BXGC0001741 3,4',5,7-Tetrahydroxy-6-methoxyflavone 316.26
BXGC0001742 Eupafolin 316.26
BXGC0001778 Scutellarein 286.24
BXGC0002025 Patuletin 332.26
BXGC0002071 Apigenin 270.24
BXGC0005678 Quercetagetin 318.24
BXGC0005683 Quercetin 302.24
BXGC0006306 Myricetin 318.24
BXGC0006635 Luteolin 286.24
BXGC0008182 6-Hydroxyluteolin 302.24
BXGC0025812 5,4'dihydroxy-3,6,7,8,3'-Pentamethoxyflavone 404.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein