adisease

Showing entry for Nasal Polyps

General Disease Information
BXGD Id	BXGD001988
Disease Name	Nasal Polyps
Disease CUI Id	C0027430
MeSH Codes	C23 C08 C09
Disease Class Name	Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15496	BXGT004175	Group 10 secretory phospholipase A2	8399	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	8989	reviewed	Ion channel
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01903	BXGT005814	HLA class II histocompatibility antigen, DR alpha chain	3122	reviewed	Immune response
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P03950	BXGT006116	Angiogenin	283	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P06126	BXGT006412	T-cell surface glycoprotein CD1a	909	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P07148	BXGT006559	Fatty acid-binding protein, liver	2168	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08670	BXGT006810	Vimentin	7431	reviewed
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10153	BXGT007544	Non-secretory ribonuclease	6036	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13671	BXGT007941	Complement component C6	729	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16109	BXGT008194	P-selectin	6403	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P20702	BXGT008592	Integrin alpha-X	3687	reviewed
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21583	BXGT008667	Kit ligand	4254	reviewed
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P28347	BXGT009257	Transcriptional enhancer factor TEF-1	7003	reviewed	Transcription factor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29017	BXGT009305	T-cell surface glycoprotein CD1c	911	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P30086	BXGT009400	Phosphatidylethanolamine-binding protein 1	5037	reviewed	Enzyme modulator
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31151	BXGT009510	Protein S100-A7	6278	reviewed	Calcium-binding protein
P32302	BXGT009619	C-X-C chemokine receptor type 5	643	reviewed	G-protein coupled receptor
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35613	BXGT009856	Basigin	682	reviewed
P35754	BXGT009863	Glutaredoxin-1	2745	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P36969	BXGT009949	Phospholipid hydroperoxide glutathione peroxidase	2879	reviewed	Enzyme
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43116	BXGT010357	Prostaglandin E2 receptor EP2 subtype	5732	reviewed	G-protein coupled receptor
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48728	BXGT010654	Aminomethyltransferase, mitochondrial	275	reviewed
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51677	BXGT010876	C-C chemokine receptor type 3	1232	reviewed	G-protein coupled receptor
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P51790	BXGT010890	H(+)/Cl(-) exchange transporter 3	1182	reviewed	Ion channel
P51884	BXGT010903	Lumican	4060	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P60568	BXGT011315	Interleukin-2	3558	reviewed
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P63316	BXGT011517	Troponin C, slow skeletal and cardiac muscles	7134	reviewed	Calcium-binding protein
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P78540	BXGT011848	Arginase-2, mitochondrial	384	reviewed	Enzyme
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q05315	BXGT012811	Galectin-10	1178	reviewed	Signaling
Q07011	BXGT012912	Tumor necrosis factor receptor superfamily member 9	3604	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	5144	reviewed
Q12794	BXGT013265	Hyaluronidase-1	3373	reviewed	Enzyme
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13304	BXGT013337	Uracil nucleotide/cysteinyl leukotriene receptor	2840	reviewed	G-protein coupled receptor
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13541	BXGT013371	Eukaryotic translation initiation factor 4E-binding protein 1	1978	reviewed	Nucleic acid binding
Q14627	BXGT013492	Interleukin-13 receptor subunit alpha-2	3598	reviewed	Signaling
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q15796	BXGT013599	Mothers against decapentaplegic homolog 2	4087	reviewed	Transcription factor
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16873	BXGT013684	Leukotriene C4 synthase	4056	reviewed	Enzyme
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q8IU54	BXGT018331	Interferon lambda-1	282618	reviewed
Q8N6P7	BXGT018524	Interleukin-22 receptor subunit alpha-1	58985	reviewed	Receptor
Q8N6T7	BXGT018525	NAD-dependent protein deacetylase sirtuin-6	51548	reviewed	Epigenetic regulator
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8NET8	BXGT018557	Transient receptor potential cation channel subfamily V member 3	162514	reviewed	Ion channel
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q8WTT0	BXGT018987	C-type lectin domain family 4 member C	170482	reviewed	Receptor
Q8WWA0	BXGT018999	Intelectin-1	55600	reviewed
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q96A83	BXGT019616	Collagen alpha-1(XXVI) chain	136227	reviewed
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q99467	BXGT019923	CD180 antigen	4064	reviewed	Receptor
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BZ11	BXGT020193	Disintegrin and metalloproteinase domain-containing protein 33	80332	reviewed	Enzyme
Q9BZP6	BXGT020201	Acidic mammalian chitinase	27159	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H015	BXGT020432	Solute carrier family 22 member 4	6583	reviewed	Transporter
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NP55	BXGT021141	BPI fold-containing family A member 1	51297	reviewed
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NPH5	BXGT021159	NADPH oxidase 4	50507	reviewed	Enzyme
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRP7	BXGT021192	Serine/threonine-protein kinase 36	27148	reviewed	Kinase
Q9NZK7	BXGT021276	Group IIE secretory phospholipase A2	30814	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UI42	BXGT021713	Carboxypeptidase A4	51200	reviewed	Enzyme
Q9UJ71	BXGT021725	C-type lectin domain family 4 member K	50489	reviewed	Receptor
Q9UKV8	BXGT021752	Protein argonaute-2	27161	reviewed
Q9UNK4	BXGT021789	Group IID secretory phospholipase A2	26279	reviewed	Enzyme
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	10800	reviewed	G-protein coupled receptor
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y5S8	BXGT022302	NADPH oxidase 1	27035	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q9UP95	BXGT024658	Solute carrier family 12 member 4	6560	reviewed	Transporter
A8K7I4	BXGT025277	Calcium-activated chloride channel regulator 1	1179	reviewed	Ion channel
Q9UGM3	BXGT025543	Deleted in malignant brain tumors 1 protein	1755	reviewed	Enzyme
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}