Showing entry for Potassium channel subfamily K member 9


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021150
Protein NamePotassium channel subfamily K member 9
Uniport IdQ9NPC2
GeneKCNK9
Gene Id51305
DomainIon_trans_2
Pfam PF07885  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa04925 Aldosterone synthesis and secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990573 potassium ion import across plasma membrane
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0030322 stabilization of membrane potential
molecular function GO:0005267 potassium channel activity
molecular function GO:0022841 potassium ion leak channel activity
molecular function GO:0005249 voltage-gated potassium channel activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296071 Potassium Channels
R-HSA-1296346 Tandem pore domain potassium channels
R-HSA-1299316 TWIK-releated acid-sensitive K+ channel (TASK)
R-HSA-397014 Muscle contraction
R-HSA-5576886 Phase 4 - resting membrane potential
R-HSA-5576891 Cardiac conduction
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001890 BXGD000088 Akinetic Petit Mal Nervous System Diseases
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014553 BXGD000931 Absence Epilepsy Nervous System Diseases
C0015826 BXGD001022 Fenestration (morphologic abnormality)
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018834 BXGD001238 Heartburn Pathological Conditions, Signs and Symptoms
C0020428 BXGD001377 Hyperaldosteronism Endocrine System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024902 BXGD001815 Mastodynia Pathological Conditions, Signs and Symptoms
C0025202 BXGD001832 melanoma Neoplasms
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026847 BXGD001940 Spinal Muscular Atrophy Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0040517 BXGD002872 Gilles de la Tourette syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0205770 BXGD004121 Choroid Plexus Papilloma Neoplasms; Nervous System Diseases
C0221358 BXGD004450 Long narrow head
C0234146 BXGD004626 Absent reflex Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235025 BXGD004713 Peripheral motor neuropathy Nervous System Diseases
C0239548 BXGD004984 Fasciculation, Tongue Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0240379 BXGD005033 Open mouth (finding)
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0264638 BXGD005405 Low-renin essential hypertension Cardiovascular Diseases
C0270971 BXGD006146 Floppy infant syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0332853 BXGD006901 Anastomosis
C0342544 BXGD007501 Idiopathic central precocious puberty Endocrine System Diseases
C0343149 BXGD007606 Contracture of joint of foot Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424503 BXGD008532 Dysmorphic facies
C0426429 BXGD008564 Broad nasal tip
C0426848 BXGD008590 Sacral dimple Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0751124 BXGD010327 Epilepsy, Absence, Atypical Nervous System Diseases
C0813217 BXGD010854 Expressionless face Nervous System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1384514 BXGD012940 Conn Syndrome Endocrine System Diseases
C1393871 BXGD012979 Congenital finger flexion contractures
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1527344 BXGD013275 Dysphonia Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1611743 BXGD013456 Familial (FPAH)
C1836543 BXGD014130 Thick vermilion border
C1837404 BXGD014229 High, narrow palate
C1839758 BXGD014402 Narrow forehead
C1839767 BXGD014404 Tented upper lip vermilion
C1853487 BXGD015340 Thick eyebrow
C1854111 BXGD015381 Broad philtrum
C1855285 BXGD015483 Protruding ear
C1856121 BXGD015578 Broad eyebrow
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1861324 BXGD016029 Short philtrum
C1868571 BXGD016508 Highly arched eyebrow
C1968605 BXGD016719 Limited elbow flexion/extension
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2674608 BXGD017250 Feeding difficulties in infancy
C2676770 BXGD017345 Birk-Barel Mental Retardation Dysmorphism Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C2749625 BXGD017629 Motor axonal neuropathy
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4022583 BXGD020924 Fatiguable weakness of proximal limb muscles
C4023175 BXGD021136 Submucous cleft soft palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C4023544 BXGD021213 Incisor macrodontia
C4281785 BXGD022415 Childhood Absence Epilepsy Nervous System Diseases
C4317339 BXGD022739 Juvenile Absence Epilepsy Nervous System Diseases
C4551564 BXGD023352 Narrow nasal bridge
C4552765 BXGD023522 Epilepsy, Minor Nervous System Diseases
C4553705 BXGD023547 Absence Seizure Disorder Nervous System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042510 Fluoxetine 309.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein