adisease

Showing entry for Neuralgia

General Disease Information
BXGD Id	BXGD002037
Disease Name	Neuralgia
Disease CUI Id	C0027796
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00139	BXGT003881	Kinesin-like protein KIF2A	3796	reviewed	Cellular structure
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00222	BXGT003899	Metabotropic glutamate receptor 8	2918	reviewed	G-protein coupled receptor
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00451	BXGT003923	GDNF family receptor alpha-2	2675	reviewed
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O14842	BXGT004106	Free fatty acid receptor 1	2864	reviewed	G-protein coupled receptor
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O43353	BXGT004589	Receptor-interacting serine/threonine-protein kinase 2	8767	reviewed	Kinase
O43612	BXGT004605	Orexin	3060	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O60885	BXGT004906	Bromodomain-containing protein 4	23476	reviewed	Epigenetic regulator
O75164	BXGT005104	Lysine-specific demethylase 4A	9682	reviewed
O75347	BXGT005113	Tubulin-specific chaperone A	6902	reviewed	Chaperone
O75366	BXGT005116	Advillin	10677	reviewed	Cellular structure
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75762	BXGT005151	Transient receptor potential cation channel subfamily A member 1	8989	reviewed	Ion channel
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O94759	BXGT005327	Transient receptor potential cation channel subfamily M member 2	7226	reviewed	Ion channel
O95069	BXGT005348	Potassium channel subfamily K member 2	3776	reviewed	Ion channel
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02654	BXGT005911	Apolipoprotein C-I	341	reviewed
P02746	BXGT005938	Complement C1q subcomponent subunit B	713	reviewed
P02760	BXGT005948	Protein AMBP	259	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02795	BXGT005968	Metallothionein-2	4502	reviewed
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05129	BXGT006322	Protein kinase C gamma type	5582	reviewed	Kinase
P05161	BXGT006331	Ubiquitin-like protein ISG15	9636	reviewed	Nucleic acid binding
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P05556	BXGT006368	Integrin beta-1	3688	reviewed	Receptor
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08758	BXGT006821	Annexin A5	308	reviewed
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09958	BXGT006950	Furin	5045	reviewed	Enzyme
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	5292	reviewed	Kinase
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12429	BXGT007814	Annexin A3	306	reviewed
P12830	BXGT007852	Cadherin-1	999	reviewed
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P13866	BXGT007963	Sodium/glucose cotransporter 1	6523	reviewed	Transporter
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14618	BXGT008027	Pyruvate kinase PKM	5315	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14920	BXGT008067	D-amino-acid oxidase	1610	reviewed
P15309	BXGT008105	Prostatic acid phosphatase	55	reviewed	Enzyme
P15336	BXGT008109	Cyclic AMP-dependent transcription factor ATF-2	1386	reviewed	Transcription factor
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16070	BXGT008186	CD44 antigen	960	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P17655	BXGT008325	Calpain-2 catalytic subunit	824	reviewed	Enzyme
P17676	BXGT008327	CCAAT/enhancer-binding protein beta	1051	reviewed	Transcription factor
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	5770	reviewed
P18075	BXGT008375	Bone morphogenetic protein 7	655	reviewed	Signaling
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18825	BXGT008426	Alpha-2C adrenergic receptor	152	reviewed	G-protein coupled receptor
P18847	BXGT008431	Cyclic AMP-dependent transcription factor ATF-3	467	reviewed	Transcription factor
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19525	BXGT008492	Interferon-induced, double-stranded RNA-activated protein kinase	5610	reviewed	Kinase
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21453	BXGT008654	Sphingosine 1-phosphate receptor 1	1901	reviewed	G-protein coupled receptor
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23528	BXGT008879	Cofilin-1	1072	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P25024	BXGT009005	C-X-C chemokine receptor type 1	3577	reviewed	G-protein coupled receptor
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P25098	BXGT009015	Beta-adrenergic receptor kinase 1	156	reviewed	Kinase
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P25774	BXGT009066	Cathepsin S	1520	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28562	BXGT009270	Dual specificity protein phosphatase 1	1843	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29218	BXGT009322	Inositol monophosphatase 1	3612	reviewed	Enzyme
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29372	BXGT009336	DNA-3-methyladenine glycosylase	4350	reviewed	Enzyme
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P30533	BXGT009434	Alpha-2-macroglobulin receptor-associated protein	4043	reviewed
P30536	BXGT009435	Translocator protein	706	reviewed
P30542	BXGT009436	Adenosine receptor A1	134	reviewed	G-protein coupled receptor
P30626	BXGT009450	Sorcin	6717	reviewed
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P30874	BXGT009475	Somatostatin receptor type 2	6752	reviewed	G-protein coupled receptor
P31327	BXGT009523	Carbamoyl-phosphate synthase [ammonia], mitochondrial	1373	reviewed	Enzyme
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P32302	BXGT009619	C-X-C chemokine receptor type 5	643	reviewed	G-protein coupled receptor
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P35408	BXGT009828	Prostaglandin E2 receptor EP4 subtype	5734	reviewed	G-protein coupled receptor
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36507	BXGT009923	Dual specificity mitogen-activated protein kinase kinase 2	5605	reviewed	Kinase
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P41146	BXGT010226	Nociceptin receptor	4987	reviewed	G-protein coupled receptor
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	3357	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42261	BXGT010293	Glutamate receptor 1	2890	reviewed	Ion channel
P42262	BXGT010294	Glutamate receptor 2	2891	reviewed	Ion channel
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43166	BXGT010364	Carbonic anhydrase 7	766	reviewed
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P45974	BXGT010493	Ubiquitin carboxyl-terminal hydrolase 5	8078	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48067	BXGT010619	Sodium- and chloride-dependent glycine transporter 1	6536	reviewed	Transporter
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49281	BXGT010689	Natural resistance-associated macrophage protein 2	4891	reviewed	Transporter
P49286	BXGT010691	Melatonin receptor type 1B	4544	reviewed	G-protein coupled receptor
P49765	BXGT010738	Vascular endothelial growth factor B	7423	reviewed	Signaling
P49773	BXGT010741	Histidine triad nucleotide-binding protein 1	3094	reviewed	Enzyme
P49802	BXGT010746	Regulator of G-protein signaling 7	6000	reviewed
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P49902	BXGT010758	Cytosolic purine 5'-nucleotidase	22978	reviewed	Enzyme
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P50750	BXGT010818	Cyclin-dependent kinase 9	1025	reviewed	Kinase
P51575	BXGT010861	P2X purinoceptor 1	5023	reviewed	Ion channel
P51617	BXGT010868	Interleukin-1 receptor-associated kinase 1	3654	reviewed	Kinase
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51790	BXGT010890	H(+)/Cl(-) exchange transporter 3	1182	reviewed	Ion channel
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54289	BXGT011040	Voltage-dependent calcium channel subunit alpha-2/delta-1	781	reviewed	Ion channel
P54710	BXGT011070	Sodium/potassium-transporting ATPase subunit gamma	486	reviewed	Transporter
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P55212	BXGT011112	Caspase-6	839	reviewed	Enzyme
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P56373	BXGT011164	P2X purinoceptor 3	5024	reviewed	Ion channel
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P56817	BXGT011200	Beta-secretase 1	23621	reviewed	Enzyme
P57789	BXGT011221	Potassium channel subfamily K member 10	54207	reviewed	Ion channel
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P61006	BXGT011345	Ras-related protein Rab-8A	4218	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61626	BXGT011382	Lysozyme C	4069	reviewed
P62805	BXGT011457	Histone H4	8370	reviewed
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P63244	BXGT011510	Receptor of activated protein C kinase 1	10399	reviewed
P63279	BXGT011514	SUMO-conjugating enzyme UBC9	7329	reviewed
P78352	BXGT011836	Disks large homolog 4	1742	reviewed	Receptor
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P78563	BXGT011850	Double-stranded RNA-specific editase 1	104	reviewed	Enzyme
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q00975	BXGT012558	Voltage-dependent N-type calcium channel subunit alpha-1B	774	reviewed	Ion channel
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q01970	BXGT012627	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3	5331	reviewed	Enzyme
Q01974	BXGT012628	Tyrosine-protein kinase transmembrane receptor ROR2	4920	reviewed	Kinase
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q13133	BXGT013315	Oxysterols receptor LXR-alpha	10062	reviewed	Nuclear receptor
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13164	BXGT013322	Mitogen-activated protein kinase 7	5598	reviewed	Kinase
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q13451	BXGT013356	Peptidyl-prolyl cis-trans isomerase FKBP5	2289	reviewed	Enzyme
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q13547	BXGT013373	Histone deacetylase 1	3065	reviewed	Epigenetic regulator
Q13822	BXGT013396	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	5168	reviewed	Enzyme
Q13887	BXGT013401	Krueppel-like factor 5	688	reviewed	Nucleic acid binding
Q13976	BXGT013409	cGMP-dependent protein kinase 1	5592	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14164	BXGT013451	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	9641	reviewed	Kinase
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14469	BXGT013473	Transcription factor HES-1	3280	reviewed	Transcription factor
Q14624	BXGT013491	Inter-alpha-trypsin inhibitor heavy chain H4	3700	reviewed	Enzyme modulator
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q14831	BXGT013506	Metabotropic glutamate receptor 7	2917	reviewed	G-protein coupled receptor
Q14974	BXGT013516	Importin subunit beta-1	3837	reviewed	Transporter
Q15077	BXGT013533	P2Y purinoceptor 6	5031	reviewed	G-protein coupled receptor
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15835	BXGT013606	Rhodopsin kinase	6011	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16555	BXGT013638	Dihydropyrimidinase-related protein 2	1808	reviewed	Enzyme
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16658	BXGT013651	Fascin	6624	reviewed	Cellular structure
Q16659	BXGT013652	Mitogen-activated protein kinase 6	5597	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16828	BXGT013676	Dual specificity protein phosphatase 6	1848	reviewed
Q2M2I8	BXGT014130	AP2-associated protein kinase 1	22848	reviewed	Kinase
Q53H47	BXGT015014	Histone-lysine N-methyltransferase SETMAR	6419	reviewed	Epigenetic regulator
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5SQI0	BXGT015839	Alpha-tubulin N-acetyltransferase 1	79969	reviewed
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q6ZQW0	BXGT016635	Indoleamine 2,3-dioxygenase 2	169355	reviewed
Q7Z2W7	BXGT017248	Transient receptor potential cation channel subfamily M member 8	79054	reviewed	Ion channel
Q86X55	BXGT017627	Histone-arginine methyltransferase CARM1	10498	reviewed	Epigenetic regulator
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8IXJ6	BXGT018362	NAD-dependent protein deacetylase sirtuin-2	22933	reviewed	Epigenetic regulator
Q8N608	BXGT018522	Inactive dipeptidyl peptidase 10	57628	reviewed	Enzyme
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TDS4	BXGT018812	Hydroxycarboxylic acid receptor 2	338442	reviewed
Q8TDS5	BXGT018813	Oxoeicosanoid receptor 1	165140	reviewed	G-protein coupled receptor
Q8TDV0	BXGT018815	Probable G-protein coupled receptor 151	134391	reviewed	G-protein coupled receptor
Q8WTS6	BXGT018986	Histone-lysine N-methyltransferase SETD7	80854	reviewed	Epigenetic regulator
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92859	BXGT019386	Neogenin	4756	reviewed
Q96BR1	BXGT019627	Serine/threonine-protein kinase Sgk3	23678	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96GD0	BXGT019665	Pyridoxal phosphate phosphatase	57026	reviewed	Enzyme
Q96GD4	BXGT019667	Aurora kinase B	9212	reviewed	Kinase
Q96HC4	BXGT019671	PDZ and LIM domain protein 5	10611	reviewed	Cellular structure
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99523	BXGT019929	Sortilin	6272	reviewed	Transporter
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q99685	BXGT019948	Monoglyceride lipase	11343	reviewed	Enzyme
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BUB5	BXGT020133	MAP kinase-interacting serine/threonine-protein kinase 1	8569	reviewed	Kinase
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9H244	BXGT020448	P2Y purinoceptor 12	64805	reviewed	G-protein coupled receptor
Q9H2X9	BXGT020459	Solute carrier family 12 member 5	57468	reviewed	Transporter
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9HC97	BXGT020527	G-protein coupled receptor 35	2859	reviewed	G-protein coupled receptor
Q9NPC2	BXGT021150	Potassium channel subfamily K member 9	51305	reviewed	Ion channel
Q9NPH5	BXGT021159	NADPH oxidase 4	50507	reviewed	Enzyme
Q9NQS5	BXGT021167	G-protein coupled receptor 84	53831	reviewed	G-protein coupled receptor
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NR97	BXGT021182	Toll-like receptor 8	51311	reviewed
Q9UBB5	BXGT021649	Methyl-CpG-binding domain protein 2	8932	reviewed	Epigenetic regulator
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9UL51	BXGT021754	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	610	reviewed	Ion channel
Q9ULV1	BXGT021764	Frizzled-4	8322	reviewed	G-protein coupled receptor
Q9ULY5	BXGT021770	C-type lectin domain family 4 member E	26253	reviewed	Receptor
Q9UNW8	BXGT021793	Probable G-protein coupled receptor 132	29933	reviewed	G-protein coupled receptor
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
Q9Y2T6	BXGT022247	G-protein coupled receptor 55	9290	reviewed	G-protein coupled receptor
Q9Y4D7	BXGT022275	Plexin-D1	23129	reviewed
Q9Y5S8	BXGT022302	NADPH oxidase 1	27035	reviewed
Q9Y5Y9	BXGT022309	Sodium channel protein type 10 subunit alpha	6336	reviewed	Ion channel
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q9Y6R4	BXGT022340	Mitogen-activated protein kinase kinase kinase 4	4216	reviewed	Kinase
Q9Y6Y9	BXGT022346	Lymphocyte antigen 96	23643	reviewed	Receptor
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
O60936	BXGT022857	Nucleolar protein 3	8996	reviewed
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
O95399	BXGT024237	Urotensin-2	10911	reviewed
O14649	BXGT025486	Potassium channel subfamily K member 3	3777	reviewed	Ion channel
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel
Q8N122	BXGT026091	Regulatory-associated protein of mTOR	57521	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P48145	BXGT026178	Neuropeptides B/W receptor type 1	2831	reviewed	G-protein coupled receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}