Showing entry for Hyperaldosteronism


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001377
Disease NameHyperaldosteronism
Disease CUI IdC0020428
MeSH Codes C19  
Disease Class NameEndocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000818  
Human Phenotype Ontology TermAbnormality of the endocrine system
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00255 BXGT003903 Menin 4221 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O95180 BXGT005358 Voltage-dependent T-type calcium channel subunit alpha-1H 8912 reviewed Ion channel
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05023 BXGT006294 Sodium/potassium-transporting ATPase subunit alpha-1 476 reviewed Transporter
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08263 BXGT006759 Glutathione S-transferase A1 2938 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P13866 BXGT007963 Sodium/glucose cotransporter 1 6523 reviewed Transporter
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15382 BXGT008116 Potassium voltage-gated channel subfamily E member 1 3753 reviewed Ion channel
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial 1585 reviewed
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P34947 BXGT009774 G protein-coupled receptor kinase 5 2869 reviewed Kinase
P37088 BXGT009961 Amiloride-sensitive sodium channel subunit alpha 6337 reviewed Ion channel
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P48048 BXGT010610 ATP-sensitive inward rectifier potassium channel 1 3758 reviewed Ion channel
P48544 BXGT010641 G protein-activated inward rectifier potassium channel 4 3762 reviewed Ion channel
P51168 BXGT010842 Amiloride-sensitive sodium channel subunit beta 6338 reviewed Ion channel
P51170 BXGT010843 Amiloride-sensitive sodium channel subunit gamma 6340 reviewed Ion channel
P51800 BXGT010892 Chloride channel protein ClC-Ka 1187 reviewed Ion channel
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80365 BXGT011895 Corticosteroid 11-beta-dehydrogenase isozyme 2 3291 reviewed Enzyme
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13621 BXGT013383 Solute carrier family 12 member 1 6557 reviewed Transporter
Q16651 BXGT013649 Prostasin 5652 reviewed Enzyme
Q8IUQ4 BXGT018336 E3 ubiquitin-protein ligase SIAH1 6477 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q9NPC2 BXGT021150 Potassium channel subfamily K member 9 51305 reviewed Ion channel
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
O14649 BXGT025486 Potassium channel subfamily K member 3 3777 reviewed Ion channel
Q8N122 BXGT026091 Regulatory-associated protein of mTOR 57521 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease