adisease

Showing entry for Heartburn

General Disease Information
BXGD Id	BXGD001238
Disease Name	Heartburn
Disease CUI Id	C0018834
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Sign or Symptom
Human Phenotype Ontology Id	HP:0025031
Human Phenotype Ontology Term	Abnormality of the digestive system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00482	BXGT003929	Nuclear receptor subfamily 5 group A member 2	2494	reviewed	Nuclear receptor
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O95639	BXGT005388	Cleavage and polyadenylation specificity factor subunit 4	10898	reviewed	Enzyme
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00915	BXGT005689	Carbonic anhydrase 1	759	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02144	BXGT005853	Myoglobin	4151	reviewed
P02549	BXGT005890	Spectrin alpha chain, erythrocytic 1	6708	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16070	BXGT008186	CD44 antigen	960	reviewed
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P19634	BXGT008504	Sodium/hydrogen exchanger 1	6548	reviewed	Transporter
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P30536	BXGT009435	Translocator protein	706	reviewed
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31941	BXGT009585	DNA dC->dU-editing enzyme APOBEC-3A	200315	reviewed
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P52799	BXGT010956	Ephrin-B2	1948	reviewed	Signaling
P54707	BXGT011068	Potassium-transporting ATPase alpha chain 2	479	reviewed	Transporter
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P56537	BXGT011177	Eukaryotic translation initiation factor 6	3692	reviewed	Nucleic acid binding
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60903	BXGT011339	Protein S100-A10	6281	reviewed	Calcium-binding protein
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q08257	BXGT012975	Quinone oxidoreductase	1429	reviewed
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	2559	reviewed	Ion channel
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q7Z2W7	BXGT017248	Transient receptor potential cation channel subfamily M member 8	79054	reviewed	Ion channel
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TDS5	BXGT018813	Oxoeicosanoid receptor 1	165140	reviewed	G-protein coupled receptor
Q8TDV0	BXGT018815	Probable G-protein coupled receptor 151	134391	reviewed	G-protein coupled receptor
Q9NPC2	BXGT021150	Potassium channel subfamily K member 9	51305	reviewed	Ion channel
Q9NR19	BXGT021175	Acetyl-coenzyme A synthetase, cytoplasmic	55902	reviewed	Enzyme
Q9UHC3	BXGT021695	Acid-sensing ion channel 3	9311	reviewed	Ion channel
Q9UJV9	BXGT021731	Probable ATP-dependent RNA helicase DDX41	51428	reviewed
Q9ULV1	BXGT021764	Frizzled-4	8322	reviewed	G-protein coupled receptor
Q15878	BXGT022659	Voltage-dependent R-type calcium channel subunit alpha-1E	777	reviewed	Ion channel
O14649	BXGT025486	Potassium channel subfamily K member 3	3777	reviewed	Ion channel
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}