adisease

Showing entry for Conn Syndrome

General Disease Information
BXGD Id	BXGD012940
Disease Name	Conn Syndrome
Disease CUI Id	C1384514
MeSH Codes	C19
Disease Class Name	Endocrine System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000818
Human Phenotype Ontology Term	Abnormality of the endocrine system
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O75369	BXGT005119	Filamin-B	2317	reviewed
O95180	BXGT005358	Voltage-dependent T-type calcium channel subunit alpha-1H	8912	reviewed	Ion channel
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01148	BXGT005739	Progonadoliberin-1	2796	reviewed
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P05023	BXGT006294	Sodium/potassium-transporting ATPase subunit alpha-1	476	reviewed	Transporter
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08686	BXGT006813	Steroid 21-hydroxylase	1589	reviewed
P14060	BXGT007978	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	3283	reviewed	Enzyme
P15085	BXGT008077	Carboxypeptidase A1	1357	reviewed	Enzyme
P15538	BXGT008137	Cytochrome P450 11B1, mitochondrial	1584	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P17612	BXGT008322	cAMP-dependent protein kinase catalytic subunit alpha	5566	reviewed	Kinase
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18847	BXGT008431	Cyclic AMP-dependent transcription factor ATF-3	467	reviewed	Transcription factor
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P25713	BXGT009062	Metallothionein-3	4504	reviewed
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P48544	BXGT010641	G protein-activated inward rectifier potassium channel 4	3762	reviewed	Ion channel
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16874	BXGT013685	Cytochrome P450 21-hydroxylase	1589	unreviewed
Q8IUQ4	BXGT018336	E3 ubiquitin-protein ligase SIAH1	6477	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q9NPC2	BXGT021150	Potassium channel subfamily K member 9	51305	reviewed	Ion channel
Q9NPG2	BXGT021155	Neuroglobin	58157	reviewed	Transporter
O95399	BXGT024237	Urotensin-2	10911	reviewed
O14649	BXGT025486	Potassium channel subfamily K member 3	3777	reviewed	Ion channel
Q08477	BXGT026164	Docosahexaenoic acid omega-hydroxylase CYP4F3	4051	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}