Showing entry for Deglutition Disorders


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000700
Disease NameDeglutition Disorders
Disease CUI IdC0011168
MeSH Codes C06   C09  
Disease Class NameDigestive System Diseases; Otorhinolaryngologic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0025031   HP:0000707   HP:0000152  
Human Phenotype Ontology TermAbnormality of the digestive system; Abnormality of the nervous system; Abnormality of head or neck
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta 2563 reviewed Ion channel
O14818 BXGT004103 Proteasome subunit alpha type-7 5688 reviewed
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 4864 reviewed Transporter
O15399 BXGT004164 Glutamate receptor ionotropic, NMDA 2D 2906 reviewed Ion channel
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60930 BXGT004910 Ribonuclease H1 246243 reviewed
O60931 BXGT004911 Cystinosin 1497 reviewed
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95169 BXGT005356 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 4714 reviewed Enzyme
O95263 BXGT005366 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 8622 reviewed
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02708 BXGT005927 Acetylcholine receptor subunit alpha 1134 reviewed Ion channel
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03891 BXGT006110 NADH-ubiquinone oxidoreductase chain 2 4536 reviewed
P03897 BXGT006111 NADH-ubiquinone oxidoreductase chain 3 4537 reviewed
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P03923 BXGT006115 NADH-ubiquinone oxidoreductase chain 6 4541 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P04350 BXGT006193 Tubulin beta-4A chain 10382 reviewed Cellular structure
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05129 BXGT006322 Protein kinase C gamma type 5582 reviewed Kinase
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07451 BXGT006627 Carbonic anhydrase 3 761 reviewed
P07602 BXGT006646 Prosaposin 5660 reviewed
P07737 BXGT006663 Profilin-1 5216 reviewed
P07814 BXGT006680 Bifunctional glutamate/proline--tRNA ligase 2058 reviewed Enzyme
P08034 BXGT006716 Gap junction beta-1 protein 2705 reviewed Cell-cell junction
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09417 BXGT006888 Dihydropteridine reductase 5860 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11678 BXGT007736 Eosinophil peroxidase 8288 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12235 BXGT007774 ADP/ATP translocase 1 291 reviewed Transporter
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P16144 BXGT008200 Integrin beta-4 3691 reviewed Receptor
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P26640 BXGT009123 Valine--tRNA ligase 7407 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 5605 reviewed Kinase
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P42858 BXGT010341 Huntingtin 3064 reviewed
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P45381 BXGT010460 Aspartoacylase 443 reviewed
P48067 BXGT010619 Sodium- and chloride-dependent glycine transporter 1 6536 reviewed Transporter
P48637 BXGT010649 Glutathione synthetase 2937 reviewed Enzyme
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P49448 BXGT010709 Glutamate dehydrogenase 2, mitochondrial 2747 reviewed Enzyme
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49959 BXGT010766 Double-strand break repair protein MRE11 4361 reviewed
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54707 BXGT011068 Potassium-transporting ATPase alpha chain 2 479 reviewed Transporter
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P56556 BXGT011179 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 4700 reviewed Enzyme
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P58400 BXGT011235 Neurexin-1-beta 9378 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P84074 BXGT012030 Neuron-specific calcium-binding protein hippocalcin 3208 reviewed
Q02108 BXGT012634 Guanylate cyclase soluble subunit alpha-1 2982 reviewed
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03393 BXGT012711 6-pyruvoyl tetrahydrobiopterin synthase 5805 reviewed
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q04844 BXGT012789 Acetylcholine receptor subunit epsilon 1145 reviewed Ion channel
Q06210 BXGT012864 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 2673 reviewed Enzyme
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07001 BXGT012907 Acetylcholine receptor subunit delta 1144 reviewed Ion channel
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q09013 BXGT013023 Myotonin-protein kinase 1760 reviewed Kinase
Q12840 BXGT013269 Kinesin heavy chain isoform 5A 3798 reviewed Cellular structure
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13255 BXGT013332 Metabotropic glutamate receptor 1 2911 reviewed G-protein coupled receptor
Q13303 BXGT013336 Voltage-gated potassium channel subunit beta-2 8514 reviewed Ion channel
Q13472 BXGT013360 DNA topoisomerase 3-alpha 7156 reviewed Enzyme
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14003 BXGT013434 Potassium voltage-gated channel subfamily C member 3 3748 reviewed Ion channel
Q14004 BXGT013435 Cyclin-dependent kinase 13 8621 reviewed Kinase
Q14108 BXGT013440 Lysosome membrane protein 2 950 reviewed Receptor
Q14149 BXGT013449 MORC family CW-type zinc finger protein 3 23515 reviewed
Q14204 BXGT013456 Cytoplasmic dynein 1 heavy chain 1 1778 reviewed Enzyme
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q14973 BXGT013515 Sodium/bile acid cotransporter 6554 reviewed Transporter
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15223 BXGT013551 Nectin-1 5818 reviewed
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q16795 BXGT013671 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial 4704 reviewed Enzyme
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q7Z3B3 BXGT017249 KAT8 regulatory NSL complex subunit 1 284058 reviewed
Q8N183 BXGT018497 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 91942 reviewed
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q96BN8 BXGT019625 Ubiquitin thioesterase otulin 90268 reviewed
Q96FE5 BXGT019657 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 84894 reviewed Receptor
Q96PY6 BXGT019712 Serine/threonine-protein kinase Nek1 4750 reviewed Kinase
Q96QK1 BXGT019720 Vacuolar protein sorting-associated protein 35 55737 reviewed Transporter
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BQP7 BXGT020114 Mitochondrial genome maintenance exonuclease 1 92667 reviewed
Q9BU61 BXGT020131 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 25915 reviewed
Q9BUF5 BXGT020135 Tubulin beta-6 chain 84617 reviewed Cellular structure
Q9BV79 BXGT020141 Enoyl-[acyl-carrier-protein] reductase, mitochondrial 51102 reviewed
Q9BZ23 BXGT020194 Pantothenate kinase 2, mitochondrial 80025 reviewed Kinase
Q9GZV3 BXGT020427 High affinity choline transporter 1 60482 reviewed Transporter
Q9H4W6 BXGT020478 Transcription factor COE3 253738 reviewed
Q9HA77 BXGT020504 Probable cysteine--tRNA ligase, mitochondrial 79587 reviewed Enzyme
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase 57704 reviewed
Q9NPC2 BXGT021150 Potassium channel subfamily K member 9 51305 reviewed Ion channel
Q9NY46 BXGT021248 Sodium channel protein type 3 subunit alpha 6328 reviewed Ion channel
Q9NZJ4 BXGT021274 Sacsin 26278 reviewed
Q9UBE0 BXGT021651 SUMO-activating enzyme subunit 1 10055 reviewed Enzyme
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9UK17 BXGT021735 Potassium voltage-gated channel subfamily D member 3 3752 reviewed Ion channel
Q9UPN3 BXGT021797 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 23499 reviewed Cellular structure
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9Y263 BXGT022220 Phospholipase A-2-activating protein 9373 reviewed Enzyme modulator
Q9Y2Z4 BXGT022251 Tyrosine--tRNA ligase, mitochondrial 51067 reviewed Enzyme
Q9Y3I1 BXGT022260 F-box only protein 7 25793 reviewed
Q9Y4D7 BXGT022275 Plexin-D1 23129 reviewed
Q9Y5K3 BXGT022294 Choline-phosphate cytidylyltransferase B 9468 reviewed
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
P35523 BXGT023831 Chloride channel protein 1 1180 reviewed Ion channel
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q9UNE7 BXGT025000 E3 ubiquitin-protein ligase CHIP 10273 reviewed
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
Q8IZA0 BXGT025026 Dyslexia-associated protein KIAA0319-like protein 79932 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
Q6IQ55 BXGT025689 Tau-tubulin kinase 2 146057 reviewed Kinase
P61916 BXGT025881 NPC intracellular cholesterol transporter 2 10577 reviewed
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease