Showing entry for 5'-AMP-activated protein kinase subunit gamma-3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021682
Protein Name5'-AMP-activated protein kinase subunit gamma-3
Uniport IdQ9UGI9
GenePRKAG3
Gene Id53632
DomainCBS
Pfam PF00571  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
5. Organismal Systems 5.9 Aging hsa04211 Longevity regulating pathway
5. Organismal Systems 5.9 Aging hsa04213 Longevity regulating pathway - multiple species
3. Environmental Information Processing 3.2 Signal transduction hsa04371 Apelin signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.10 Environmental adaptation hsa04710 Circadian rhythm
5. Organismal Systems 5.10 Environmental adaptation hsa04714 Thermogenesis
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04920 Adipocytokine signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04921 Oxytocin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04931 Insulin resistance
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04932 Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases 6.6 Cardiovascular diseases hsa05410 Hypertrophic cardiomyopathy (HCM)
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0006633 fatty acid biosynthetic process
Biological Process GO:0005978 glycogen biosynthetic process
Biological Process GO:0006096 glycolytic process
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0016236 macroautophagy
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0050790 regulation of catalytic activity
Biological Process GO:0016241 regulation of macroautophagy
Biological Process GO:0071900 regulation of protein serine/threonine kinase activity
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0014873 response to muscle activity involved in regulation of muscle adaptation
molecular function GO:0004679 AMP-activated protein kinase activity
molecular function GO:0016208 AMP binding
molecular function GO:0005524 ATP binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0019887 protein kinase regulator activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005615 extracellular space
cellular component GO:0005654 nucleoplasm
cellular component GO:0031588 nucleotide-activated protein kinase complex
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1592230 Mitochondrial biogenesis
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-1632852 Macroautophagy
R-HSA-165159 MTOR signalling
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-199991 Membrane Trafficking
R-HSA-212436 Generic Transcription Pathway
R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-438064 Post NMDA receptor activation events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-5628897 TP53 Regulates Metabolic Genes
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-5653656 Vesicle-mediated transport
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-9612973 Autophagy
R-HSA-9612973 Autophagy
R-HSA-9613354 Lipophagy
R-HSA-9619483 Activation of AMPK downstream of NMDARs
R-HSA-9663891 Selective autophagy
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007001 BXGD000421 Carbohydrate Metabolism, Inborn Errors Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0023772 BXGD001696 Lipid Metabolism, Inborn Errors Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0043202 BXGD003037 Wolff-Parkinson-White Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0267971 BXGD005798 Storage disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C3887972 BXGD019936 GLYCOGEN CONTENT IN SKELETAL MUSCLE, INCREASED
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000528 Salicylic acid 138.12
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0002750 Vicenin 626.52
BXGC0002953 2-Phenethyl isothiocyanate 163.24
BXGC0003631 Phytosterol 414.72
BXGC0005793 Baicalein 270.24
BXGC0006466 Oleanolic acid 456.71
BXGC0012352 Chelerythrine 348.12
BXGC0014173 petasin 316.2
BXGC0016548 30-Norhederagenin 456.32
BXGC0024261 Adenosine Phosphate 347.06
BXGC0024554 D-luciferin 280
BXGC0030663 Metformin 129.1
BXGC0031558 Baicalin 446.08
BXGC0032381 Daucosterol 576.44
BXGC0034941 Combretastatin A4 316.13
BXGC0035226 Betulinic Acid 456.36
BXGC0037499 Palbinone 358.21
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047088 Ursolic Acid 456.36
BXGC0047281 Berberine 336.12
BXGC0053261 Antimycin A 548.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein