Showing entry for Salicylic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0000528
Compound NameSalicylic acid
Structure
FormulaC7H6O3
InchiKeyYGSDEFSMJLZEOE-UHFFFAOYSA-N
SMILESOC(=O)C1=CC=CC=C1O
InchiInChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
IUPAC2-hydroxybenzoic acid
Molecular Weight138.12
Pubchem Id338
Chembl IdCHEMBL424
Targets of Information Source
DrugBank DB00936
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 approved; investigational; vet_approved inhibitor
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 approved; investigational; vet_approved inhibitor
Q04828 BXGT012787 Aldo-keto reductase family 1 member C1 reviewed Enzyme AKR1C1 approved; investigational; vet_approved inhibitor
PDB SAL
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P80457 BXGT011911 Xanthine dehydrogenase/oxidase reviewed XDH - - - - -
P27245 BXGT009166 Multiple antibiotic resistance protein MarR reviewed marR - - - - -
Q9SPV4 BXGT021599 Salicylate carboxymethyltransferase reviewed SAMT - - - - -
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed PTGS1 - - - - -
P22985 BXGT008824 Xanthine dehydrogenase/oxidase reviewed Xdh - - - - -
Q6RYA0 BXGT016513 Salicylic acid-binding protein 2 reviewed SABP2 - - - 90 -
P47989 BXGT010602 Xanthine dehydrogenase/oxidase reviewed XDH Enzyme - - - -
Q9X9I8 BXGT022158 Salicylate synthetase, Irp9 unreviewed irp9 - - - - -
P02768 BXGT005955 Serum albumin reviewed ALB Transporter - - - -
Q7WT50 BXGT017192 LysR-type regulatory protein unreviewed dntR - - - 11800 -
Q7WT50 BXGT017192 LysR-type regulatory protein unreviewed dntR - - - - -
O26413 BXGT004275 Transcriptional regulator unreviewed MTH_313 - - - 500000 -
P40676 BXGT010194 Transcriptional regulator SlyA reviewed slyA - - - - -
Q96ZY1 BXGT019764 Putative MarR family transcriptional regulator unreviewed ST1710 - - - 20000000 -
Q51507 BXGT014952 Isochorismate pyruvate lyase reviewed pchB - - - - -
Q5HLN6 BXGT015416 Transcriptional regulator TcaR unreviewed tcaR - - - - -
Q67FT0 BXGT016179 Gentisate 1,2-dioxygenase unreviewed C7441_11945 - - - - -
P9WFX5 BXGT012254 Anthranilate phosphoribosyltransferase reviewed trpD - - - - -
P22830 BXGT008809 Ferrochelatase, mitochondrial reviewed FECH Enzyme - - - -
Q9L2B5 BXGT021041 Putative transcriptional regulator unreviewed SCO5405 - - - - -
Q6GEG9 BXGT016299 Uncharacterized HTH-type transcriptional regulator SAR2349 reviewed SAR2349 - - - - -
Q9LYU4 BXGT021095 4-substituted benzoates-glutamate ligase GH3.12 reviewed GH3.12 - - - - -
Q1LCS4 BXGT013813 3-hydroxyanthranilate 3,4-dioxygenase reviewed nbaC - - - - -
Q86U86 BXGT017611 Protein polybromo-1 reviewed PBRM1 Epigenetic regulator - - - -
Q59713 BXGT015262 Salicylate hydroxylase unreviewed sal - - - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed PTGS2 Enzyme - - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed CA2 - - - - -
P54507 BXGT011050 Major biofilm matrix component reviewed tasA - - - - -
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha reviewed PIK3R1 Kinase - - - -
O22822 BXGT004216 UDP-glycosyltransferase 74F2 reviewed UGT74F2 - - - - -
A0A140DJY3 BXGT000649 Salicylate-AMP ligase unreviewed cahJ - - - - -
P9WME9 BXGT012386 Uncharacterized HTH-type transcriptional regulator Rv2887 reviewed Rv2887 - - - - 24500
A0A452CSM5 BXGT023558 Vicilin-like antimicrobial peptides 2-2 unreviewed - - - - -
Q9BPX1 BXGT020103 17-beta-hydroxysteroid dehydrogenase 14 reviewed HSD17B14 Enzyme - - - -
P0CT50 BXGT024532 Salicylate decarboxylase reviewed sdc - - - - -
B0JEU3 BXGT024745 Vicilin unreviewed vicilin - - - - -
Q5ICL9 BXGT025934 Regulatory protein NPR4 reviewed NPR4 - - - - -
P9WFX1 BXGT012252 Salicylate synthase reviewed mbtI - - - - -
Binding DB 26193
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 9900 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 7100 - - -
reviewed BXGT006627 Carbonic anhydrase 3 reviewed CA3 885000 - - -
reviewed BXGT008802 Carbonic anhydrase 4 reviewed CA4 11100 - - -
reviewed BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed CA5A 678000 - - -
reviewed BXGT008844 Carbonic anhydrase 6 reviewed CA6 11900 - - -
reviewed BXGT010364 Carbonic anhydrase 7 reviewed CA7 82100 - - -
reviewed BXGT013670 Carbonic anhydrase 9 reviewed CA9 78700 - - -
reviewed BXGT004601 Carbonic anhydrase 12 reviewed CA12 8800 - - -
reviewed BXGT020260 Carbonic anhydrase 13 reviewed Ca13 67000 - - -
reviewed BXGT021769 Carbonic anhydrase 14 reviewed CA14 49800 - - -
reviewed BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed CA5B 355000 - - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 >10000 - - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 >10000 - - -
reviewed BXGT008271 Prolyl 4-hydroxylase subunit alpha-1 reviewed P4HA1 2300000 - - -
reviewed BXGT008083 Aldo-keto reductase family 1 member B1 reviewed Enzyme AKR1B1 - >1000000 - -
reviewed BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP >1800 - - -
reviewed BXGT006758 Stromelysin-1 reviewed Enzyme MMP3 - - >25000000 -
reviewed BXGT018997 Ubiquitin-like domain-containing CTD phosphatase 1 reviewed UBLCP1 - 66000000 - -
reviewed BXGT005373 Bile salt export pump reviewed Transporter ABCB11 - >1000000 - -
reviewed BXGT005057 Bile salt export pump reviewed Abcb11 - >1000000 - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 - 560000 - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 - 680000 - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 620000 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 740000 - - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 500000 - -
reviewed BXGT004563 Polyphenol oxidase 2 reviewed PPO2 - 100000 - -
reviewed BXGT008844 Carbonic anhydrase 6 reviewed CA6 2320000 - - -
reviewed BXGT019994 Carbonic anhydrase 15 reviewed Ca15 7200 - - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 9920 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 7120 - - -
reviewed BXGT018912 Solute carrier family 22 member 6 reviewed Slc22a6 145000 - - -
reviewed BXGT017282 Solute carrier family 22 member 20 reviewed Slc22a20 44000 - - -
reviewed BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed PTPN1 19400000 - - -
reviewed BXGT006070 Polymerase acidic protein reviewed PA - - - >250000
reviewed BXGT004543 Solute carrier family 22 member 6 reviewed Slc22a6 1000000 - - -
reviewed BXGT018794 Solute carrier family 22 member 8 reviewed Transporter SLC22A8 1020000 - - -
reviewed BXGT004543 Solute carrier family 22 member 6 reviewed Slc22a6 341000 - - -
reviewed BXGT011911 Xanthine dehydrogenase/oxidase reviewed XDH 100000000 - - -
CHEMBL CHEMBL424
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 39810 nM
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Inhibition '=' 12 %
Q8TCC7 BXGT018794 Solute carrier family 22 member 8 reviewed Transporter SLC22A8 Activity - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P08236 BXGT006752 Beta-glucuronidase reviewed - GUSB Inhibition '=' 23 %
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 reviewed Enzyme AKR1B1 Inhibition '=' 0 %
P08253 BXGT006757 72 kDa type IV collagenase reviewed Enzyme MMP2 Inhibition '=' 12 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Ki '>' 1800 nM
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 9920 nM
P79208 BXGT011858 Prostaglandin G/H synthase 2 reviewed - PTGS2 Inhibition - - -
P35030 BXGT009784 Trypsin-3 reviewed Enzyme PRSS3 Inhibition '=' 86 %
P07478 BXGT006630 Trypsin-2 reviewed Enzyme PRSS2 Inhibition '=' 86 %
P07477 BXGT006629 Trypsin-1 reviewed Enzyme PRSS1 Inhibition '=' 86 %
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Activity - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ki '=' 2320000 nM
Q2PCB5 BXGT014154 Carbonic anhydrase unreviewed - ca Ki '=' 324000 nM
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 Ki '=' 78700 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 reviewed - UGT1A9 Activity - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 '=' 680000 nM
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 Ki '=' 885000 nM
Q9NSA0 BXGT021202 Solute carrier family 22 member 11 reviewed Transporter SLC22A11 Activity - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
Q80UJ1 BXGT017282 Solute carrier family 22 member 20 reviewed - Slc22a20 Ki '=' 44000 nM
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P80457 BXGT011911 Xanthine dehydrogenase/oxidase reviewed - XDH Ki '=' 100000000 nM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 Ki '=' 8800 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 24 %
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P08254 BXGT006758 Stromelysin-1 reviewed Enzyme MMP3 Kd '>' 25000000 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 Ki '=' 19400000 nM
P08538 BXGT006787 Tyrosine-protein phosphatase YopH reviewed - yopH Ki '=' 1000000 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B Ki '=' 355000 nM
Q8TCC7 BXGT018794 Solute carrier family 22 member 8 reviewed Transporter SLC22A8 Ki '=' 1020000 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 Kis '=' 19400 uM
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 Activity '=' 84 %
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 28183 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 31622 nM
O35956 BXGT004543 Solute carrier family 22 member 6 reviewed - Slc22a6 Activity - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 1000000 nM
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
Q4R6F8 BXGT014886 T-complex protein 1 subunit beta reviewed - CCT2 Potency - 70794 nM
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Ki '=' 5 nM
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 Activity '=' 19 mM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki '=' 7120 nM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 620000 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 63095 nM
Q9D6N1 BXGT020260 Carbonic anhydrase 13 reviewed - Ca13 Ki '=' 67000 nM
P35218 BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed - CA5A Ki '=' 678000 nM
Q8VC69 BXGT018912 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 145000 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 ID50 '=' 3 mM
Q9ULX7 BXGT021769 Carbonic anhydrase 14 reviewed - CA14 Ki '=' 49800 nM
P08254 BXGT006758 Stromelysin-1 reviewed Enzyme MMP3 Inhibition '=' -2 %
Q969S8 BXGT019613 Polyamine deacetylase HDAC10 reviewed Epigenetic regulator HDAC10 Activity '=' 92 %
Q9UKV0 BXGT021750 Histone deacetylase 9 reviewed Epigenetic regulator HDAC9 Activity '=' 92 %
P56524 BXGT011176 Histone deacetylase 4 reviewed Epigenetic regulator HDAC4 Activity '=' 92 %
Q96DB2 BXGT019639 Histone deacetylase 11 reviewed Epigenetic regulator HDAC11 Activity '=' 92 %
Q9BY41 BXGT020180 Histone deacetylase 8 reviewed Epigenetic regulator HDAC8 Activity '=' 92 %
Q8WUI4 BXGT018992 Histone deacetylase 7 reviewed Epigenetic regulator HDAC7 Activity '=' 92 %
Q9UQL6 BXGT021813 Histone deacetylase 5 reviewed Epigenetic regulator HDAC5 Activity '=' 92 %
Q92769 BXGT019370 Histone deacetylase 2 reviewed Epigenetic regulator HDAC2 Activity '=' 92 %
Q9UBN7 BXGT021658 Histone deacetylase 6 reviewed Epigenetic regulator HDAC6 Activity '=' 92 %
O15379 BXGT004159 Histone deacetylase 3 reviewed Epigenetic regulator HDAC3 Activity '=' 92 %
Q13547 BXGT013373 Histone deacetylase 1 reviewed Epigenetic regulator HDAC1 Activity '=' 92 %
Q80UJ1 BXGT017282 Solute carrier family 22 member 20 reviewed - Slc22a20 Ki '=' 43651 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 97 %
P22894 BXGT008815 Neutrophil collagenase reviewed Enzyme MMP8 Inhibition '=' 14 %
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Log K' '=' 0 -
Q9UGI9 BXGT021682 5'-AMP-activated protein kinase subunit gamma-3 reviewed Enzyme modulator PRKAG3 Ratio '=' 1 -
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Ratio '=' 1 -
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 reviewed Kinase PRKAB1 Ratio '=' 1 -
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 reviewed Enzyme modulator PRKAG2 Ratio '=' 1 -
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 Ratio '=' 1 -
O43741 BXGT004620 5'-AMP-activated protein kinase subunit beta-2 reviewed Enzyme modulator PRKAB2 Ratio '=' 1 -
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 Ratio '=' 1 -
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ki '=' 11900 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 500000 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 24 %
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 15 %
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P08236 BXGT006752 Beta-glucuronidase reviewed - GUSB Inhibition '=' 26 %
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 IC50 '=' 560000 nM
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 Ki '=' 82100 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki '=' 7100 nM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 9900 nM
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
P15917 BXGT008169 Lethal factor reviewed - lef Inhibition '=' 6 %
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P53987 BXGT011023 Monocarboxylate transporter 1 reviewed - Slc16a1 Activity - - -
P08487 BXGT006778 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 reviewed - PLCG1 IC50 '=' 120 ug.mL-1
Q8VC69 BXGT018912 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 144543 nM
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 Ki '=' 7200 nM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 reviewed Enzyme AKR1B1 IC50 '>' 1000000 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P08236 BXGT006752 Beta-glucuronidase reviewed - GUSB Inhibition '=' 24 %
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
Q9UGI9 BXGT021682 5'-AMP-activated protein kinase subunit gamma-3 reviewed Enzyme modulator PRKAG3 A0.5 '=' 1 mM
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 A0.5 '=' 1 mM
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 reviewed Kinase PRKAB1 A0.5 '=' 1 mM
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 reviewed Enzyme modulator PRKAG2 A0.5 '=' 1 mM
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 A0.5 '=' 1 mM
O43741 BXGT004620 5'-AMP-activated protein kinase subunit beta-2 reviewed Enzyme modulator PRKAB2 A0.5 '=' 1 mM
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 A0.5 '=' 1 mM
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 1995 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki '=' 740000 nM
Q5RLM2 BXGT015647 Solute carrier family 22 member 7 reviewed - Slc22a7 Km '=' 88800 nM
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 28183 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 35481 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 23 %
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta reviewed Kinase IKBKB INH '>' 1000 uM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Inhibition '=' 13 %
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 IC50 '=' 100000 nM
Q91WU2 BXGT019304 Solute carrier family 22 member 7 reviewed - Slc22a7 Activity - - -
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ki '=' 11100 nM
P09429 BXGT006889 High mobility group protein B1 reviewed Nucleic acid binding HMGB1 Kd '=' 1000 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
O35956 BXGT004543 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 1000000 nM
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 Activity - - -
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 11220 nM
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P03433 BXGT006070 Polymerase acidic protein reviewed - PA EC50 '>' 250000 nM
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 reviewed - IDO1 Inhibition '=' 2 %
P35030 BXGT009784 Trypsin-3 reviewed Enzyme PRSS3 Inhibition '=' 84 %
P07478 BXGT006630 Trypsin-2 reviewed Enzyme PRSS2 Inhibition '=' 84 %
P07477 BXGT006629 Trypsin-1 reviewed Enzyme PRSS1 Inhibition '=' 84 %
Q5RLM2 BXGT015647 Solute carrier family 22 member 7 reviewed - Slc22a7 Km '=' 81200 nM
O35956 BXGT004543 Solute carrier family 22 member 6 reviewed - Slc22a6 Ki '=' 341000 nM
O88909 BXGT005288 Solute carrier family 22 member 8 reviewed - Slc22a8 Activity - - -
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed Kinase PIK3CA Inhibition '<' 25 %
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha reviewed Kinase PIK3R1 Inhibition '<' 25 %
P06133 BXGT006414 UDP-glucuronosyltransferase 2B4 reviewed - UGT2B4 Activity '=' 0 pm/min/mg
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
O88909 BXGT005288 Solute carrier family 22 member 8 reviewed - Slc22a8 Activity '=' 11 %
P36537 BXGT009924 UDP-glucuronosyltransferase 2B10 reviewed - UGT2B10 Activity '=' 0 pm/min/mg
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 reviewed Transporter SLC22A6 IC50 '=' 280000 nM
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P09917 BXGT006941 Arachidonate 5-lipoxygenase reviewed Enzyme ALOX5 Inhibition '=' 20 %
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Inhibition '=' -1 %
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
Q8VCA0 BXGT018913 Solute carrier family 22 member 19 reviewed - Slc22a19 Activity '=' 30 %
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 7 %
Q8WVY7 BXGT018997 Ubiquitin-like domain-containing CTD phosphatase 1 reviewed - UBLCP1 IC50 '=' 66000000 nM
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed Kinase PIK3CA Inhibition '<' 25 %
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 32196 nM
Q9WU19 BXGT026124 Hydroxyacid oxidase 1 reviewed - Hao1 Inhibition '=' 18 %
O70127 BXGT005057 Bile salt export pump reviewed - Abcb11 IC50 '>' 1000000 nM
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00011 Cashew nut Anacardium occidentale Nuts
BXGF00016 Peanut Arachis hypogaea Nuts
BXGF00019 Tarragon Artemisia dracunculus Herbs and Spices
BXGF00034 Broccoli Brassica oleracea var. italica Vegetables
BXGF00038 Tea Camellia sinensis Teas
BXGF00050 Chinese cinnamon Cinnamomum aromaticum Herbs and Spices
BXGF00051 Ceylon cinnamon Cinnamomum verum Herbs and Spices
BXGF00056 Mandarin orange (Clementine, Tangerine) Citrus reticulata Fruits
BXGF00063 Saffron Crocus sativus Herbs and Spices
BXGF00073 Japanese persimmon Diospyros kaki Fruits
BXGF00082 Fennel Foeniculum vulgare Herbs and Spices
BXGF00085 Soy bean Glycine max Soy
BXGF00086 Sunflower Helianthus annuus Herbs and Spices
BXGF00088 Barley Hordeum vulgare Cereals and cereal products
BXGF00106 Mango Mangifera indica Fruits
BXGF00107 German camomile Matricaria recutita Herbs and Spices
BXGF00118 Nutmeg Myristica fragrans Herbs and Spices
BXGF00120 Evening primrose Oenothera biennis Herbs and Spices
BXGF00141 Common pea Pisum sativum Pulses
BXGF00156 Redcurrant Ribes rubrum Fruits
BXGF00162 Red raspberry Rubus idaeus Fruits
BXGF00165 Common sage Salvia officinalis Herbs and Spices
BXGF00187 Common wheat Triticum aestivum Cereals and cereal products
BXGF00192 American cranberry Vaccinium macrocarpon Fruits
BXGF00193 Bilberry Vaccinium myrtillus Fruits
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00205 Corn Zea mays Cereals and cereal products
BXGF00206 Ginger Zingiber officinale Herbs and Spices
BXGF00239 Grapefruit Citrus X paradisi Fruits
BXGF00246 Red beetroot Beta vulgaris var. rubra Vegetables
BXGF00248 Beer Beverages
BXGF00315 Cottonseed Gossypium Herbs and Spices
BXGF00369 Sacred lotus Nelumbo nucifera Vegetables
BXGF00570 Grape wine Beverages
BXGF00802 Soft-necked garlic Allium sativum L. var. sativum Herbs and Spices
BXGF00871 Citrus unshiu Citrus unshiu Medicinal Plant
BXGF00956 Passiflora incarnata Passiflora incarnata Medicinal Plant
BXGF00997 Bletilla striata Bletilla striata Medicinal Plant
BXGF01074 Centella asiatica Centella asiatica Medicinal Plant
BXGF01157 Alstonia muelleriana Alstonia muelleriana Others
BXGF01205 Dacrydium cupressinum Dacrydium cupressinum Medicinal Plant
BXGF01448 Trigonella grandiflora Trigonella grandiflora Others
BXGF01554 Nicotiana undulata Nicotiana undulata Others
BXGF01821 Artemisia cina Artemisia cina Medicinal Plant
BXGF01841 Cedronella canariensis Cedronella canariensis Medicinal Plant
BXGF01991 Rosa rugosa Rosa rugosa Medicinal Plant
BXGF02024 Actaea dahurica Actaea dahurica Human Edible Plant
BXGF02121 Humata pectinata Humata pectinata Others
BXGF02143 Actaea cimicifuga Actaea cimicifuga Medicinal Plant
BXGF02164 Isodon japonica var. glaucocalyx Isodon japonica var. glaucocalyx Others
BXGF02193 Broussonetia kazinoki Broussonetia kazinoki Medicinal Plant
BXGF02551 Inula britannica Inula britannica Medicinal Plant
BXGF02623 Physalis edulis Physalis edulis Others
BXGF02737 Artemisia scoparia Artemisia scoparia Medicinal Plant
BXGF02757 Tripolium pannonicum Tripolium pannonicum Others
BXGF02786 Rubus coreanus Rubus coreanus Human Edible Plant
BXGF02787 Melia azedarach Melia azedarach Medicinal Plant
BXGF02841 Gleditsia caspica Gleditsia caspica Medicinal Plant
BXGF02925 Coreopsis nodosa Coreopsis nodosa Others
BXGF03180 Uvaria calamistrata Uvaria calamistrata Medicinal Plant
BXGF03234 Plantago major Plantago major Medicinal Plant
BXGF03410 Polygonatum cyrtonema Polygonatum cyrtonema Medicinal Plant
BXGF03488 Paeonia suffruticosa Paeonia suffruticosa Medicinal Plant
BXGF03508 Haematococcus lacustris Haematococcus lacustris Others
BXGF03718 Swertia angustifolia Swertia angustifolia Medicinal Plant
BXGF04007 Bistorta vivipara Bistorta vivipara Medicinal Plant
BXGF04235 Rubus chingii Rubus chingii Food Plant
BXGF04271 Artemisia annua Artemisia annua Medicinal Plant
BXGF04309 Pteris multifida Pteris multifida Medicinal Plant
BXGF04329 Swertia swertopsis Swertia swertopsis Others
BXGF04337 Premna tomentosa Premna tomentosa Medicinal Plant
BXGF04348 Sagittaria sagittifolia Sagittaria sagittifolia Medicinal Plant
BXGF04359 Cunonia macrophylla Cunonia macrophylla Medicinal Plant
BXGF04367 Tsuga chinensis Tsuga chinensis Medicinal Plant
BXGF04369 Taxus brevifolia Taxus brevifolia Medicinal Plant
BXGF04373 Virgilia divaricata Virgilia divaricata Others
BXGF04378 Entada rheedei Entada rheedei Medicinal Plant
BXGF04394 Aucuba chinensis Aucuba chinensis Others
BXGF04398 Utricularia australis Utricularia australis Others
BXGF04402 Actaea simplex Actaea simplex Others
BXGF04403 Amsinckia tessellata Amsinckia tessellata Others
BXGF04404 Carica dodecaphylla Carica dodecaphylla Others
BXGF04406 Citrus tangerina Citrus tangerina Human Edible Plant
BXGF04411 Crocus minimus Crocus minimus Human Edible Plant
BXGF04414 Curculigo pilosa Curculigo pilosa Medicinal Plant
BXGF04416 Sideritis euboea Sideritis euboea Others
BXGF04423 Osteospermum muricatum Osteospermum muricatum Others
BXGF04425 Centaurea huber-morathii Centaurea huber-morathii Others
BXGF04429 Sisyrinchium californicum Sisyrinchium californicum Others
BXGF04432 Saussurea amara Saussurea amara Others
BXGF04439 Lysiana subfalcata Lysiana subfalcata Human Edible Plant
BXGF04441 Haplophyllum ramosissimum Haplophyllum ramosissimum Others
BXGF04446 Peperomia vulcanica Peperomia vulcanica Medicinal Plant
BXGF04456 Sorbus tianschanica Sorbus tianschanica Medicinal Plant
BXGF04463 Platycarya strobilacea Platycarya strobilacea Medicinal Plant
BXGF04474 Helichrysum mixtum Helichrysum mixtum Others
BXGF04478 Cynometra lujae Cynometra lujae Others
BXGF04482 Aspalathus linearis Aspalathus linearis Medicinal Plant
BXGF04486 Eupatorium areolare Eupatorium areolare Others
BXGF04492 Stephania elegans Stephania elegans Medicinal Plant
BXGF04759 Calendula officinalis Calendula officinalis Medicinal Plant
BXGF04820 Panax ginseng Panax ginseng 0
BXGF04825 Polygonatum kingianum Polygonatum kingianum Medicinal Plant
BXGF04843 Brickellia vernicosa Brickellia vernicosa Others
BXGF04850 Macaranga peltata Macaranga peltata Medicinal Plant
BXGF04978 Isatis indigotica Isatis indigotica Medicinal Plant
BXGF05203 Chlamydomonas reinhardtii Chlamydomonas reinhardtii Others
BXGF05297 Isatis tinctoria Isatis tinctoria Medicinal Plant
BXGF05354 Tabebuia avellanedae Tabebuia avellanedae Medicinal Plant
BXGF05365 Aconitum carmichaelii Aconitum carmichaelii Medicinal Plant
BXGF05413 Glycine tomentella Glycine tomentella Human Edible Plant
BXGF05476 Broussonetia papyrifera Broussonetia papyrifera Medicinal Plant
BXGF05564 Polygonatum falcatum Polygonatum falcatum Medicinal Plant
BXGF05705 Pseudostellaria heterophylla Pseudostellaria heterophylla Medicinal Plant
BXGF05749 Kali turgidum Kali turgidum Medicinal Plant
BXGF05817 Panax schinseng Panax schinseng Others
BXGF05819 Citrus aurantium Citrus aurantium Medicinal Plant
BXGF05851 Aconitum japonicum Aconitum japonicum Medicinal Plant
BXGF05944 Senecio paludaffinis Senecio paludaffinis Others
BXGF05962 Rehmannia glutinosa Rehmannia glutinosa Medicinal Plant
BXGF05977 Schisandra chinensis Schisandra chinensis Medicinal Plant
BXGF06273 Parablechnum minus Parablechnum minus Others
BXGF06312 Polygonatum sibiricum Polygonatum sibiricum Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease