Showing entry for Alpha-crystallin A chain


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026168
Protein NameAlpha-crystallin A chain
Uniport IdP02489
GeneCRYAA
Gene Id102724652;1409
DomainCrystallin; HSP20
Pfam PF00525   PF00011  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0032387 negative regulation of intracellular transport
Biological Process GO:0050821 protein stabilization
Biological Process GO:0050896 response to stimulus
Biological Process GO:0007601 visual perception
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0005212 structural constituent of eye lens
molecular function GO:0005198 structural molecule activity
molecular function GO:0051082 unfolded protein binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001857 BXGD000085 AIDS related complex Infections; Immune System Diseases
C0002418 BXGD000112 Amblyopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0009363 BXGD000599 Congenital ocular coloboma (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0009691 BXGD000622 Congenital cataract Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
C0010036 BXGD000642 Corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0010038 BXGD000643 Corneal Opacity Eye Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0016952 BXGD001085 Galactosemias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0029531 BXGD002164 Other cataract Eye Diseases
C0036646 BXGD002627 Age-related cataract Eye Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0042164 BXGD002965 Uveitis Eye Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0158551 BXGD003890 Embryonal nuclear cataract (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0240063 BXGD005015 Coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266539 BXGD005689 Congenital total cataract Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266544 BXGD005691 Microcornea Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266551 BXGD005693 Congenital coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0271160 BXGD006166 Cortical cataract Eye Diseases
C0392557 BXGD008056 Nuclear cataract Eye Diseases
C0521707 BXGD009166 Bilateral cataracts (disorder) Eye Diseases
C0524524 BXGD009228 Pseudoaphakia Eye Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C1112705 BXGD011681 Nuclear non-senile cataract Eye Diseases
C1510497 BXGD013174 Lens Opacities Eye Diseases
C1855179 BXGD015468 CATARACT, ANTERIOR POLAR Eye Diseases
C1858679 BXGD015818 CATARACT, AUTOSOMAL DOMINANT Eye Diseases
C1861821 BXGD016076 CATARACT, MARNER TYPE Eye Diseases
C1861829 BXGD016080 Cataract microcornea syndrome Eye Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C3888098 BXGD019950 Cataract, Autosomal Recessive Congenital 1 Eye Diseases
C4015984 BXGD020254 CATARACT 9, AUTOSOMAL RECESSIVE
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006990 Lanosterol 426.72
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein