Showing entry for Congenital cataract


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000622
Disease NameCongenital cataract
Disease CUI IdC0009691
MeSH Codes C23   C16   C13   C11   C10  
Disease Class NamePathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id HP:0000478  
Human Phenotype Ontology TermAbnormality of the eye
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14770 BXGT004095 Homeobox protein Meis2 4212 reviewed Enzyme
O43597 BXGT004602 Protein sprouty homolog 2 10253 reviewed Signaling
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P07437 BXGT006624 Tubulin beta chain 203068 reviewed Cellular structure
P08670 BXGT006810 Vimentin 7431 reviewed
P08700 BXGT006816 Interleukin-3 3562 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17980 BXGT008362 26S proteasome regulatory subunit 6A 5702 reviewed Enzyme
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P24666 BXGT008986 Low molecular weight phosphotyrosine protein phosphatase 52 reviewed
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29400 BXGT009343 Collagen alpha-5(IV) chain 1287 reviewed
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P35579 BXGT009852 Myosin-9 4627 reviewed
P48449 BXGT010632 Lanosterol synthase 4047 reviewed
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P50542 BXGT010808 Peroxisomal targeting signal 1 receptor 5830 reviewed Transporter
P51570 BXGT010858 Galactokinase 2584 reviewed Kinase
P53673 BXGT011010 Beta-crystallin A4 1413 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q71U36 BXGT016705 Tubulin alpha-1A chain 7846 reviewed Cellular structure
Q8IWS0 BXGT018356 PHD finger protein 6 84295 reviewed Nucleic acid binding
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8NHU6 BXGT018569 Tudor domain-containing protein 7 23424 reviewed Enzyme
Q9NQS3 BXGT021166 Nectin-3 25945 reviewed
Q9Y2S2 BXGT022245 Lambda-crystallin homolog 51084 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q5FWF4 BXGT023211 DNA annealing helicase and endonuclease ZRANB3 84083 reviewed
Q9ULV5 BXGT024442 Heat shock factor protein 4 3299 reviewed Transcription factor
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
P07315 BXGT026109 Gamma-crystallin C 1420 reviewed
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
P43320 BXGT026151 Beta-crystallin B2 1415 reviewed
P02489 BXGT026168 Alpha-crystallin A chain 1409 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease