Showing entry for 3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0011421
Compound Name3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone
Structure
FormulaC9H10O3
InchiKeyLTEPZFZSPZASKJ-UHFFFAOYSA-N
SMILESOCCC(=O)C1=CC=C(O)C=C1
InchiInChI=1S/C9H10O3/c10-6-5-9(12)7-1-3-8(11)4-2-7/h1-4,10-11H,5-6H2
IUPAC3-hydroxy-1-(4-hydroxyphenyl)propan-1-one
Molecular Weight166.17
Pubchem Id638759
Chembl IdCHEMBL1417159
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50570
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 reviewed Signaling MCL1 - 5157.654358 - -
reviewed BXGT008148 Intestinal-type alkaline phosphatase 1 reviewed Alpi - >100000 - -
reviewed BXGT006942 Intestinal-type alkaline phosphatase reviewed Enzyme ALPI - - - 11300
reviewed BXGT007603 Alkaline phosphatase, germ cell type reviewed Enzyme ALPG - - - 18900
reviewed BXGT006338 Alkaline phosphatase, tissue-nonspecific isozyme reviewed Enzyme ALPL - >100000 - -
reviewed BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 - 11881 - -
CHEMBL CHEMBL1417159
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 19952 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 44668 nM
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 89125 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 89125 nM
P05186 BXGT006338 Alkaline phosphatase, tissue-nonspecific isozyme reviewed Enzyme ALPL IC50 '>' 100000 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 37650 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 3548 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 25118 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 79432 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 10000 nM
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 17782 nM
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 1778 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 35481 nM
P10696 BXGT007603 Alkaline phosphatase, germ cell type reviewed Enzyme ALPG EC50 '=' 18900 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 8912 nM
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase reviewed Enzyme WRN Potency - 28183 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 51682 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 5011 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 25118 nM
P55212 BXGT011112 Caspase-6 reviewed Enzyme CASP6 AC50 '=' 1320 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 3548 nM
P09923 BXGT006942 Intestinal-type alkaline phosphatase reviewed Enzyme ALPI EC50 '=' 11300 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 25118 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 35481 nM
P24822 BXGT008996 Intestinal-type alkaline phosphatase reviewed - Iap IC50 '>' 100000 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency '=' 1258 nM
P03070 BXGT006016 Large T antigen reviewed - IC50 - 28790 nM
Q9Y468 BXGT022270 Lethal(3)malignant brain tumor-like protein 1 reviewed Epigenetic regulator L3MBTL1 Potency '=' 3548 nM
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 reviewed Signaling MCL1 IC50 '=' 5157 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 26854 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 41052 nM
Q13671 BXGT013391 Ras and Rab interactor 1 reviewed Enzyme modulator RIN1 IC50 '=' 11881 nM
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 IC50 '=' 11881 nM
Q4GZG4 BXGT014813 Phosphoglycerate kinase unreviewed - PGKC Potency - 1634 nM
O95398 BXGT005378 Rap guanine nucleotide exchange factor 3 reviewed Enzyme modulator RAPGEF3 Potency - 31622 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 8912 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 12589 nM
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 Potency - 79432 nM
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial reviewed Enzyme GLS Potency - 7943 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 22387 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 1584 nM
P55210 BXGT011110 Caspase-7 reviewed Enzyme CASP7 AC50 '=' 9650 nM
P42574 BXGT010317 Caspase-3 reviewed Enzyme CASP3 AC50 '=' 31720 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00823 Fruits Fruits
BXGF03919 Xanthium strumarium Xanthium strumarium Medicinal Plant
BXGF05297 Isatis tinctoria Isatis tinctoria Medicinal Plant
BXGF05511 Acorus gramineus Acorus gramineus Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease