Showing entry for Mitral Valve Insufficiency


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001895
Disease NameMitral Valve Insufficiency
Disease CUI IdC0026266
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypePathologic Function
Human Phenotype Ontology Id HP:0001626  
Human Phenotype Ontology TermAbnormality of the cardiovascular system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00459 BXGT003924 Phosphatidylinositol 3-kinase regulatory subunit beta 5296 reviewed Enzyme modulator
O15247 BXGT004142 Chloride intracellular channel protein 2 1193 reviewed Ion channel
O15553 BXGT004181 Pyrin 4210 reviewed
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O95169 BXGT005356 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial 4714 reviewed Enzyme
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P10600 BXGT007584 Transforming growth factor beta-3 proprotein 7043 reviewed Signaling
P20933 BXGT008618 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 175 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P22681 BXGT008795 E3 ubiquitin-protein ligase CBL 867 reviewed Enzyme
P24468 BXGT008969 COUP transcription factor 2 7026 reviewed Nuclear receptor
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q6MZM0 BXGT016375 Hephaestin-like protein 1 341208 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q9BU61 BXGT020131 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 25915 reviewed
Q9NX14 BXGT021242 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 54539 reviewed Enzyme
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease