Showing entry for Transcription factor COE3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020478
Protein NameTranscription factor COE3
Uniport IdQ9H4W6
GeneEBF3
Gene Id253738
DomainCOE1_DBD; COE1_HLH; TIG
Pfam PF16422   PF16423   PF01833  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0046872 metal ion binding
molecular function GO:0046983 protein dimerization activity
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003635 BXGD000214 Apraxias Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004106 BXGD000254 Astigmatism Eye Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0005697 BXGD000324 Neurogenic Urinary Bladder Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases
C0005967 BXGD000357 Bone neoplasms Neoplasms; Musculoskeletal Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014877 BXGD000967 Esotropia Eye Diseases; Nervous System Diseases
C0015310 BXGD000976 Exotropia Eye Diseases; Nervous System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020608 BXGD001443 Hypodontia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031900 BXGD002313 Pierre Robin Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0031903 BXGD002314 Pigeon Breeder's Lung Respiratory Tract Diseases; Immune System Diseases; Occupational Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038271 BXGD002742 Stereotyped Behavior Behavior and Behavior Mechanisms
C0038273 BXGD002743 Stereotypic Movement Disorder Mental Disorders
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040485 BXGD002871 Torticollis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042580 BXGD002992 Vesico-Ureteral Reflux Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0079924 BXGD003103 Oligohydramnios Female Urogenital Diseases and Pregnancy Complications
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220621 BXGD004300 Childhood Acute Myeloid Leukemia Neoplasms
C0221060 BXGD004384 Mobius Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Stomatognathic Diseases
C0221199 BXGD004403 Abnormal palmar creases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0221358 BXGD004450 Long narrow head
C0234162 BXGD004627 Cerebellar Dysmetria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234860 BXGD004698 Weak cry
C0239234 BXGD004974 Low set ears
C0239676 BXGD004989 High forehead
C0241726 BXGD005110 Delayed ability to walk
C0262361 BXGD005229 Growth abnormality
C0262655 BXGD005264 Recurrent urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0266313 BXGD005650 Allanson Pantzar McLeod syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0266617 BXGD005700 Congenital anomaly of face Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0269269 BXGD006058 Inversion of nipple (disorder) Skin and Connective Tissue Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0332615 BXGD006898 Myopathic facies
C0423110 BXGD008471 Downward slant of palpebral fissure
C0423224 BXGD008475 Sunken eyes Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0424503 BXGD008532 Dysmorphic facies
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426429 BXGD008564 Broad nasal tip
C0431447 BXGD008690 Synophrys Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0431478 BXGD008692 Posteriorly rotated ear
C0432072 BXGD008718 Dysmorphic features
C0454641 BXGD008848 Expressive language delay
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0557874 BXGD009444 Global developmental delay
C0566899 BXGD009494 Small labia majora
C0678230 BXGD009750 Congenital Epicanthus
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0856863 BXGD011122 Broad-based gait
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1512419 BXGD013189 Hereditary Melanoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1697450 BXGD013506 obsolete Prominent epicanthal folds
C1835884 BXGD014061 Triangular face
C1836038 BXGD014073 Poor head control Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1836047 BXGD014074 Long face
C1836830 BXGD014165 Developmental regression Mental Disorders
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837260 BXGD014214 Prominent forehead
C1837522 BXGD014244 Impaired pain sensation
C1837731 BXGD014260 Overfolded helix
C1839797 BXGD014409 Deep philtrum
C1840077 BXGD014434 Anteverted nostril
C1843367 BXGD014576 Poor school performance
C1844820 BXGD014681 Range of joint movement increased
C1848673 BXGD014963 Hypoplastic feet
C1849025 BXGD014997 Oval face
C1850049 BXGD015101 Clinodactyly of the 5th finger
C1854113 BXGD015382 Prominent nasal bridge
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1855333 BXGD015489 External genital hypoplasia
C1855676 BXGD015528 Aplasia/Hypoplasia of the cerebellar vermis
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1865014 BXGD016282 Long philtrum
C1865017 BXGD016283 Thin upper lip vermilion
C1865304 BXGD016309 Overfolding of the superior helices
C1866195 BXGD016385 Downturned corners of mouth
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3277019 BXGD018698 Horizontal eyebrow
C3278923 BXGD018748 Dilated ventricles (finding)
C3472614 BXGD018922 Plasmablastic lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C3697248 BXGD019355 Short lower third of face
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4012968 BXGD020124 Mild global developmental delay
C4023172 BXGD021135 Broad chin
C4025865 BXGD021835 Abnormality of facial musculature
C4310618 BXGD022600 HYPOTONIA, ATAXIA, AND DELAYED DEVELOPMENT SYNDROME
C4551492 BXGD023317 Micropenis
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein