Showing entry for Potassium voltage-gated channel subfamily KQT member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010889
Protein NamePotassium voltage-gated channel subfamily KQT member 1
Uniport IdP51787
GeneKCNQ1
Gene Id3784
DomainIon_trans; KCNQ_channel
Pfam PF00520   PF03520  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.3 Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes
5. Organismal Systems 5.6 Nervous system hsa04725 Cholinergic synapse
5. Organismal Systems 5.4 Digestive system hsa04971 Gastric acid secretion
5. Organismal Systems 5.4 Digestive system hsa04972 Pancreatic secretion
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05110 Vibrio cholerae infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0086014 atrial cardiac muscle cell action potential
Biological Process GO:0061337 cardiac conduction
Biological Process GO:0060048 cardiac muscle contraction
Biological Process GO:0072358 cardiovascular system development
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0071872 cellular response to epinephrine stimulus
Biological Process GO:0016458 gene silencing
Biological Process GO:0048839 inner ear development
Biological Process GO:0050892 intestinal absorption
Biological Process GO:0086011 membrane repolarization during action potential
Biological Process GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential
Biological Process GO:0086013 membrane repolarization during cardiac muscle cell action potential
Biological Process GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential
Biological Process GO:1902260 negative regulation of delayed rectifier potassium channel activity
Biological Process GO:1903817 negative regulation of voltage-gated potassium channel activity
Biological Process GO:0060452 positive regulation of cardiac muscle contraction
Biological Process GO:0010460 positive regulation of heart rate
Biological Process GO:1901381 positive regulation of potassium ion transmembrane transport
Biological Process GO:0097623 potassium ion export across plasma membrane
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
Biological Process GO:0060453 regulation of gastric acid secretion
Biological Process GO:0006349 regulation of gene expression by genetic imprinting
Biological Process GO:0008016 regulation of heart contraction
Biological Process GO:0086091 regulation of heart rate by cardiac conduction
Biological Process GO:0060306 regulation of membrane repolarization
Biological Process GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
Biological Process GO:0070293 renal absorption
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0086005 ventricular cardiac muscle cell action potential
molecular function GO:0005516 calmodulin binding
molecular function GO:0005251 delayed rectifier potassium channel activity
molecular function GO:0044325 ion channel binding
molecular function GO:0015271 outward rectifier potassium channel activity
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
molecular function GO:0034236 protein kinase A catalytic subunit binding
molecular function GO:0034237 protein kinase A regulatory subunit binding
molecular function GO:0008157 protein phosphatase 1 binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0005249 voltage-gated potassium channel activity
molecular function GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
molecular function GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
molecular function GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005769 early endosome
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0016021 integral component of membrane
cellular component GO:0034702 ion channel complex
cellular component GO:0005770 late endosome
cellular component GO:0005764 lysosome
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296071 Potassium Channels
R-HSA-1296072 Voltage gated Potassium channels
R-HSA-397014 Muscle contraction
R-HSA-5576890 Phase 3 - rapid repolarisation
R-HSA-5576891 Cardiac conduction
R-HSA-5576893 Phase 2 - plateau phase
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001075 BXGD000020 Achlorhydria Digestive System Diseases; Nutritional and Metabolic Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003868 BXGD000233 Arthritis, Gouty Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004245 BXGD000264 Atrioventricular Block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0004903 BXGD000293 Beckwith-Wiedemann Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0005612 BXGD000317 Birth Weight Pathological Conditions, Signs and Symptoms
C0005890 BXGD000345 Body Height
C0005893 BXGD000346 Body mass index procedure
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011053 BXGD000694 Deafness Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0011071 BXGD000696 Sudden death Pathological Conditions, Signs and Symptoms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015930 BXGD001025 Fetal Distress Pathological Conditions, Signs and Symptoms
C0016049 BXGD001039 Fibromatosis, Gingival Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0017155 BXGD001098 Gastritis, Hypertrophic Digestive System Diseases
C0017654 BXGD001136 Glomerular Filtration Rate
C0018099 BXGD001172 Gout Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0018781 BXGD001219 Noise-induced hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018808 BXGD001229 Heart murmur Pathological Conditions, Signs and Symptoms
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020621 BXGD001449 Hypokalemia Nutritional and Metabolic Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021841 BXGD001519 Intestinal Neoplasms Digestive System Diseases; Neoplasms
C0022387 BXGD001543 Jervell-Lange Nielsen Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023976 BXGD001724 Long QT Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024421 BXGD001770 Macroglossia Stomatognathic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024796 BXGD001806 Marfan Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C0025568 BXGD001877 Metaplasia Pathological Conditions, Signs and Symptoms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027709 BXGD002026 Nephrocalcinosis Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030252 BXGD002199 Palpitations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0035828 BXGD002566 Romano-Ward Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038644 BXGD002776 Sudden infant death syndrome Pathological Conditions, Signs and Symptoms
C0039070 BXGD002787 Syncope Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0039231 BXGD002799 Tachycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0040479 BXGD002870 Torsades de Pointes Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0041657 BXGD002929 Unconscious State Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042510 BXGD002987 Ventricular Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042514 BXGD002989 Tachycardia, Ventricular Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042580 BXGD002992 Vesico-Ureteral Reflux Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042798 BXGD003003 Low Vision Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0043202 BXGD003037 Wolff-Parkinson-White Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0079035 BXGD003061 Bradyarrhythmia (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085298 BXGD003155 Sudden Cardiac Death Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0085610 BXGD003202 Sinus bradycardia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0086209 BXGD003270 Emotional Stress Behavior and Behavior Mechanisms
C0086543 BXGD003294 Cataract Eye Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151636 BXGD003451 Premature ventricular contractions Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151878 BXGD003495 Prolonged QT interval Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151879 BXGD003496 Shortened QT interval Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152459 BXGD003600 Linear atrophy Pathological Conditions, Signs and Symptoms
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155708 BXGD003814 Other specified conduction disorders Cardiovascular Diseases
C0158986 BXGD003916 Neonatal hypoglycemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0162316 BXGD003936 Iron deficiency anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0175693 BXGD004001 Russell-Silver syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201976 BXGD004063 Creatinine measurement, serum (procedure)
C0202236 BXGD004086 Triglycerides measurement
C0202239 BXGD004087 Uric acid measurement (procedure)
C0205641 BXGD004093 Adenocarcinoma, Basal Cell Neoplasms
C0205642 BXGD004094 Adenocarcinoma, Oxyphilic Neoplasms
C0205643 BXGD004095 Carcinoma, Cribriform Neoplasms
C0205644 BXGD004096 Carcinoma, Granular Cell Neoplasms
C0205645 BXGD004097 Adenocarcinoma, Tubular Neoplasms
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206661 BXGD004224 Gonadoblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0206743 BXGD004285 Rhabdoid Tumor Neoplasms
C0221002 BXGD004360 Hyperparathyroidism, Primary Endocrine System Diseases
C0221766 BXGD004478 Diastasis recti Musculoskeletal Diseases; Wounds and Injuries
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235659 BXGD004763 Reduced fetal movement Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0235752 BXGD004766 Port-Wine Stain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266292 BXGD005643 Congenital anomaly of the kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0266589 BXGD005698 Congenital ear anomaly NOS (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Otorhinolaryngologic Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0271561 BXGD006213 Somatotropin deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0278479 BXGD006509 Stage II Colon Cancer Digestive System Diseases; Neoplasms
C0278480 BXGD006510 Stage III Colon Cancer Digestive System Diseases; Neoplasms
C0278498 BXGD006521 Malignant neoplasm of stomach stage IV
C0282488 BXGD006804 Interstitial Cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0332890 BXGD006909 Congenital hemihypertrophy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0337438 BXGD007159 Glucose measurement
C0339789 BXGD007282 Congenital deafness Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases; Otorhinolaryngologic Diseases
C0340489 BXGD007336 Lone atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0340493 BXGD007338 Paroxysmal familial ventricular fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C0344432 BXGD007670 Ventricular tachycardia, polymorphic Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0346627 BXGD007830 Intestinal Cancer Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349530 BXGD007916 Early gastric cancer Digestive System Diseases; Neoplasms
C0349788 BXGD007956 Arrhythmogenic Right Ventricular Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0391957 BXGD008019 idiopathic epilepsy
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0403654 BXGD008302 Bladder outflow obstruction
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426440 BXGD008568 Large nostrils
C0428886 BXGD008640 Mean blood pressure
C0428908 BXGD008641 Sinus Node Dysfunction (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0428977 BXGD008644 Bradycardia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0429028 BXGD008646 QT interval feature (observable entity)
C0431352 BXGD008669 Secondary microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0452138 BXGD008831 Sensorineural hearing loss, bilateral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0456132 BXGD008869 Large fontanelle
C0476287 BXGD008987 Breath-holding spell
C0489786 BXGD009018 Height
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0495706 BXGD009038 elevated blood glucose level
C0521707 BXGD009166 Bilateral cataracts (disorder) Eye Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0542518 BXGD009278 Enlarged kidney
C0545053 BXGD009323 Advanced bone age
C0557874 BXGD009444 Global developmental delay
C0578022 BXGD009541 Finding of body mass index
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600040 BXGD009684 Chronic interstitial cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C0741923 BXGD010045 cardiac event
C0748607 BXGD010201 Recurrent seizure Nervous System Diseases
C0751534 BXGD010494 Syncopal Episode Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0795690 BXGD010728 Congenital omphalocele Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0855329 BXGD011084 Electrocardiogram change
C0857439 BXGD011149 Pituitary hormone deficiency
C0871470 BXGD011316 Systolic Pressure
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948163 BXGD011511 Leukoaraiosis Pathological Conditions, Signs and Symptoms
C0948379 BXGD011533 Impaired insulin secretion
C1112433 BXGD011667 Thromboembolic stroke Cardiovascular Diseases
C1141890 BXGD011721 Congenital long QT syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1142166 BXGD011736 Brugada Syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306620 BXGD012371 Systolic blood pressure measurement
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1333015 BXGD012581 Childhood Kidney Wilms Tumor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1398312 BXGD012999 Narrow palate
C1504532 BXGD013149 Post transplant diabetes mellitus
C1560249 BXGD013361 Adverse Event Associated with Cardiac Arrhythmia
C1560305 BXGD013362 Prolonged QTc interval
C1563715 BXGD013389 Andersen Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1611743 BXGD013456 Familial (FPAH)
C1629609 BXGD013479 Age at menopause
C1631597 BXGD013480 VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1720983 BXGD013698 Channelopathies Pathological Conditions, Signs and Symptoms
C1832370 BXGD013832 MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C1832916 BXGD013883 Timothy syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Mental Disorders; Cardiovascular Diseases
C1836542 BXGD014129 Depressed nasal bridge
C1837014 BXGD014184 Atrial Fibrillation, Familial, 3 Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1837260 BXGD014214 Prominent forehead
C1839341 BXGD014370 Abnormal T-wave
C1843687 BXGD014602 ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1843738 BXGD014605 LONG QT SYNDROME 1, ACQUIRED, SUSCEPTIBILITY TO
C1845123 BXGD014714 Generalized neonatal hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1849265 BXGD015028 Overgrowth
C1851720 BXGD015229 Adrenocortical cytomegaly
C1851722 BXGD015230 Overgrowth of external genitalia
C1851733 BXGD015231 Pancreatic hyperplasia
C1853241 BXGD015321 Flat face
C1853242 BXGD015322 Midface retrusion
C1853737 BXGD015356 Prominent occiput
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1857949 BXGD015758 Prominent metopic ridge
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859062 BXGD015847 LONG QT SYNDROME 3 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1865018 BXGD016284 Short QT Syndrome 3 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1865019 BXGD016285 SHORT QT SYNDROME 2 (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1865020 BXGD016286 Short QT Syndrome 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1865866 BXGD016345 Congenital sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1867743 BXGD016470 Premature coronary artery atherosclerosis Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1960469 BXGD016664 Left ventricular noncompaction Cardiovascular Diseases
C1963175 BXGD016687 Sinus Bradycardia, CTCAE
C1963217 BXGD016689 Prolonged QTc Interval, CTCAE
C1969144 BXGD016760 Renal cortical cysts
C2108107 BXGD016920 continuous electrocardiogram sinus bradycardia (finding)
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2348199 BXGD017054 Short Qt Syndrome Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2677180 BXGD017366 Congenital microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2732413 BXGD017554 Postexertional fatigue Pathological Conditions, Signs and Symptoms
C2732979 BXGD017560 Acquired long QT syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3146254 BXGD018263 Stage III Colon Cancer AJCC v7
C3146257 BXGD018265 Stage II Colon Cancer AJCC v7
C3150943 BXGD018362 Long Qt Syndrome 2 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C3160712 BXGD018467 Palpitations, CTCAE
C3250443 BXGD018584 MYOTONIC DYSTROPHY 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C3277700 BXGD018719 LONG QT SYNDROME 1/2, DIGENIC (disorder)
C3496069 BXGD019017 cocaine use
C3668948 BXGD019321 Circling behavior
C3698186 BXGD019366 Cardiac channelopathy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C3714796 BXGD019434 Isolated somatotropin deficiency
C3887873 BXGD019922 Hearing Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4017089 BXGD020400 LONG QT SYNDROME 1, RECESSIVE
C4021539 BXGD020661 Posterior helix pit
C4021637 BXGD020711 Abnormality of the nares
C4021770 BXGD020767 Clinodactyly of toe
C4021866 BXGD020823 obsolete Abnormal heart morphology
C4023338 BXGD021156 Profound sensorineural hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4024923 BXGD021476 Diffuse white matter abnormalities Pathological Conditions, Signs and Symptoms
C4025797 BXGD021795 Abnormality of prenatal development or birth
C4042861 BXGD021881 Obesity, Metabolically Benign Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C4049938 BXGD021956 Physical Activity Measurement
C4477077 BXGD022917 Abnormal cardiac exercise stress test
C4525119 BXGD023118 Stage II Colon Cancer AJCC v8
C4525124 BXGD023120 Stage III Colon Cancer AJCC v8
C4551472 BXGD023303 Hypertrophic obstructive cardiomyopathy Cardiovascular Diseases
C4551509 BXGD023329 Jervell And Lange-Nielsen Syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4551647 BXGD023381 Long QT Syndrome 1 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002043 Acacetin 284.26
BXGC0002591 Potassium 39.1
BXGC0042114 Solifenacin 362.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein