adisease

Showing entry for Hyperpigmentation

General Disease Information
BXGD Id	BXGD003988
Disease Name	Hyperpigmentation
Disease CUI Id	C0162834
MeSH Codes	C17
Disease Class Name	Skin and Connective Tissue Diseases
Semantic Type	Pathologic Function
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15538	BXGT008137	Cytochrome P450 11B1, mitochondrial	1584	reviewed
P21583	BXGT008667	Kit ligand	4254	reviewed
P22557	BXGT008783	5-aminolevulinate synthase, erythroid-specific, mitochondrial	212	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q12791	BXGT013264	Calcium-activated potassium channel subunit alpha-1	3778	reviewed	Ion channel
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6ZVN8	BXGT016641	Hemojuvelin	148738	reviewed
Q93009	BXGT019455	Ubiquitin carboxyl-terminal hydrolase 7	7874	reviewed	Enzyme
Q99835	BXGT019969	Smoothened homolog	6608	reviewed	G-protein coupled receptor
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9Y4I1	BXGT022278	Unconventional myosin-Va	4644	reviewed	Cellular structure
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}