Showing entry for Bile salt sulfotransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012880
Protein NameBile salt sulfotransferase
Uniport IdQ06520
GeneSULT2A1
Gene Id6822
DomainSulfotransfer_1
Pfam PF00685  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450
5. Organismal Systems 5.4 Digestive system hsa04976 Bile secretion
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
Biological Process GO:0030573 bile acid catabolic process
Biological Process GO:0006068 ethanol catabolic process
Biological Process GO:0019216 regulation of lipid metabolic process
Biological Process GO:0008202 steroid metabolic process
Biological Process GO:0051923 sulfation
molecular function GO:0047704 bile-salt sulfotransferase activity
molecular function GO:0050294 steroid sulfotransferase activity
molecular function GO:0008146 sulfotransferase activity
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-156580 Phase II - Conjugation of compounds
R-HSA-156584 Cytosolic sulfonation of small molecules
R-HSA-1989781 PPARA activates gene expression
R-HSA-211859 Biological oxidations
R-HSA-400206 Regulation of lipid metabolism by PPARalpha
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0001622 BXGD000065 Adrenal Gland Hyperfunction Endocrine System Diseases
C0001624 BXGD000067 Adrenal Gland Neoplasms Neoplasms; Endocrine System Diseases
C0001627 BXGD000068 Congenital adrenal hyperplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009663 BXGD000618 Condylomata Acuminata Infections; Skin and Connective Tissue Diseases
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0017638 BXGD001132 Glioma Neoplasms
C0018081 BXGD001171 Gonorrhea Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020757 BXGD001466 Ichthyoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0020758 BXGD001467 Congenital ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0026936 BXGD001950 Mycoplasma Infections Infections
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028945 BXGD002099 oligodendroglioma Neoplasms
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030354 BXGD002214 Papilloma Neoplasms
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0033375 BXGD002405 Prolactinoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033581 BXGD002410 prostatitis Male Urogenital Diseases
C0035243 BXGD002522 Respiratory Tract Infections Infections; Respiratory Tract Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036916 BXGD002643 Sexually Transmitted Diseases Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0038015 BXGD002726 Spondyloepiphyseal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0039128 BXGD002794 Syphilis Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0041408 BXGD002923 Turner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0041976 BXGD002946 Urethritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085166 BXGD003136 Bacterial Vaginosis Female Urogenital Diseases and Pregnancy Complications; Infections
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0149985 BXGD003399 Syphilis, secondary Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0151281 BXGD003409 Genital ulcers
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0201983 BXGD004064 Dehydroepiandrosterone sulfate measurement (procedure)
C0206081 BXGD004152 Hyperandrogenism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0206667 BXGD004228 Adrenal Cortical Adenoma Neoplasms; Endocrine System Diseases
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0221715 BXGD004468 Intestinal carcinoma Digestive System Diseases; Neoplasms
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242216 BXGD005141 Biliary calculi Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242510 BXGD005173 Drug usage Chemically-Induced Disorders; Mental Disorders
C0264700 BXGD005415 Acute Inferior Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0265253 BXGD005484 Stickler syndrome (disorder) Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases
C0265279 BXGD005496 Kniest dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Respiratory Tract Diseases; Endocrine System Diseases; Stomatognathic Diseases
C0265496 BXGD005539 Tetrasomy X Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0271093 BXGD006162 Stargardt's disease
C0275524 BXGD006376 Coinfection Infections
C0276093 BXGD006400 edema disease Infections
C0279070 BXGD006625 Adult Oligodendroglioma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280475 BXGD006749 Childhood Oligodendroglioma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0338831 BXGD007216 Manic Mental Disorders
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0342546 BXGD007502 Premature adrenarche
C0343641 BXGD007636 Human papilloma virus infection Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0441683 BXGD008809 Hormone measurement
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0518948 BXGD009072 Chlamydia trachomatis infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0520463 BXGD009085 Chronic active hepatitis Digestive System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0566602 BXGD009489 Primary sclerosing cholangitis Digestive System Diseases
C0574785 BXGD009506 Lower Urinary Tract Symptoms Pathological Conditions, Signs and Symptoms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700345 BXGD009886 Candidiasis, Vulvovaginal Female Urogenital Diseases and Pregnancy Complications; Infections
C0729353 BXGD009924 Subfertility Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0747249 BXGD010166 Paranoid ideation
C0751396 BXGD010425 Well Differentiated Oligodendroglioma Neoplasms
C0877015 BXGD011327 Pelvic Organ Prolapse Pathological Conditions, Signs and Symptoms
C1112709 BXGD011682 non-gonococcal urethritis (NGU) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1621895 BXGD013466 Adrenal hyperplasia Pathological Conditions, Signs and Symptoms; Neoplasms; Endocrine System Diseases
C1955741 BXGD016606 Glucocorticoid deficiency
C2020284 BXGD016881 Stickler syndrome, type 1 Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2745959 BXGD017570 Spondyloepiphyseal dysplasia, congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2936179 BXGD018103 Obesity, Visceral Nutritional and Metabolic Diseases
C3553449 BXGD019174 PONTOCEREBELLAR HYPOPLASIA, TYPE 1B
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4255010 BXGD022310 Non-ST Elevated Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4290046 BXGD022507 trachomatis
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0002591 Potassium 39.1
BXGC0006362 Estrone 270.37
BXGC0020800 Testosterone 288.21
BXGC0029355 Pregnenolone 316.24
BXGC0037407 Lithocholic Acid 376.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein