adisease

Showing entry for Chronic otitis media

General Disease Information
BXGD Id	BXGD006203
Disease Name	Chronic otitis media
Disease CUI Id	C0271441
MeSH Codes	C09
Disease Class Name	Otorhinolaryngologic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715 HP:0000598
Human Phenotype Ontology Term	Abnormality of the immune system; Abnormality of the ear
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00204	BXGT003893	Sulfotransferase family cytosolic 2B member 1	6820	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O96028	BXGT005417	Histone-lysine N-methyltransferase NSD2	7468	reviewed	Epigenetic regulator
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15814	BXGT008159	Immunoglobulin lambda-like polypeptide 1	3543	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20933	BXGT008618	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	175	reviewed	Enzyme
P21675	BXGT008678	Transcription initiation factor TFIID subunit 1	6872	reviewed	Kinase
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35579	BXGT009852	Myosin-9	4627	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P54819	BXGT011084	Adenylate kinase 2, mitochondrial	204	reviewed	Kinase
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60033	BXGT011286	CD81 antigen	975	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q01974	BXGT012628	Tyrosine-protein kinase transmembrane receptor ROR2	4920	reviewed	Kinase
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q8WXI8	BXGT019014	C-type lectin domain family 4 member D	338339	reviewed
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q96RJ3	BXGT019729	Tumor necrosis factor receptor superfamily member 13C	115650	reviewed
Q9NRP7	BXGT021192	Serine/threonine-protein kinase 36	27148	reviewed	Kinase
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
Q96PS8	BXGT023994	Aquaporin-10	89872	reviewed	Ion channel
Q15583	BXGT024027	Homeobox protein TGIF1	7050	reviewed	Enzyme
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}