adisease

Showing entry for Muscle damage

General Disease Information
BXGD Id	BXGD008408
Disease Name	Muscle damage
Disease CUI Id	C0410158
MeSH Codes
Disease Class Name
Semantic Type	Acquired Abnormality
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O14924	BXGT004111	Regulator of G-protein signaling 12	6002	reviewed
O43451	BXGT004594	Maltase-glucoamylase, intestinal	8972	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
P00709	BXGT005621	Alpha-lactalbumin	3906	reviewed
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02144	BXGT005853	Myoglobin	4151	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	3309	reviewed
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14410	BXGT008009	Sucrase-isomaltase, intestinal	6476	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P17655	BXGT008325	Calpain-2 catalytic subunit	824	reviewed	Enzyme
P18075	BXGT008375	Bone morphogenetic protein 7	655	reviewed	Signaling
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P20810	BXGT008602	Calpastatin	831	reviewed
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P23946	BXGT008932	Chymase	1215	reviewed	Enzyme
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P50416	BXGT010797	Carnitine O-palmitoyltransferase 1, liver isoform	1374	reviewed	Enzyme
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P53985	BXGT011022	Monocarboxylate transporter 1	6566	reviewed	Transporter
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q14149	BXGT013449	MORC family CW-type zinc finger protein 3	23515	reviewed
Q15067	BXGT013532	Peroxisomal acyl-coenzyme A oxidase 1	51	reviewed	Enzyme
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16566	BXGT013639	Calcium/calmodulin-dependent protein kinase type IV	814	reviewed	Kinase
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q32MK0	BXGT014323	Myosin light chain kinase 3	91807	reviewed	Kinase
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q8IVS2	BXGT018349	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial	27349	reviewed
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92736	BXGT019367	Ryanodine receptor 2	6262	reviewed	Ion channel
Q969Q1	BXGT019610	E3 ubiquitin-protein ligase TRIM63	84676	reviewed
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9H1R3	BXGT020446	Myosin light chain kinase 2, skeletal/cardiac muscle	85366	reviewed	Kinase
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9ULC4	BXGT021757	Malignant T-cell-amplified sequence 1	28985	reviewed	Receptor
Q9Y2T3	BXGT022246	Guanine deaminase	9615	reviewed	Enzyme
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q01995	BXGT022678	Transgelin	6876	reviewed	Cellular structure
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
Q9NZM1	BXGT023948	Myoferlin	26509	reviewed	Transporter
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}