Showing entry for IMMUNE SUPPRESSION


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD014439
Disease NameIMMUNE SUPPRESSION
Disease CUI IdC1840264
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15389 BXGT004161 Sialic acid-binding Ig-like lectin 5 8778 reviewed Receptor
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43278 BXGT004581 Kunitz-type protease inhibitor 1 6692 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O94768 BXGT005331 Serine/threonine-protein kinase 17B 9262 reviewed Kinase
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95786 BXGT005396 Probable ATP-dependent RNA helicase DDX58 23586 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24666 BXGT008986 Low molecular weight phosphotyrosine protein phosphatase 52 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27540 BXGT009190 Aryl hydrocarbon receptor nuclear translocator 405 reviewed Transcription factor
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO 558 reviewed Kinase
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41273 BXGT010251 Tumor necrosis factor ligand superfamily member 9 8744 reviewed
P41743 BXGT010270 Protein kinase C iota type 5584 reviewed Kinase
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P48775 BXGT010662 Tryptophan 2,3-dioxygenase 6999 reviewed Enzyme
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase 22978 reviewed Enzyme
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q04759 BXGT012781 Protein kinase C theta type 5588 reviewed Kinase
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q12866 BXGT013273 Tyrosine-protein kinase Mer 10461 reviewed Kinase
Q12918 BXGT013280 Killer cell lectin-like receptor subfamily B member 1 3820 reviewed
Q14653 BXGT013494 Interferon regulatory factor 3 3661 reviewed Transcription factor
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q92905 BXGT019393 COP9 signalosome complex subunit 5 10987 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P2W7 BXGT021306 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 27087 reviewed Enzyme
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UIB8 BXGT021715 SLAM family member 5 8832 reviewed
Q9UQF0 BXGT021812 Syncytin-1 30816 reviewed
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
Q15583 BXGT024027 Homeobox protein TGIF1 7050 reviewed Enzyme
P31358 BXGT025061 CAMPATH-1 antigen 1043 reviewed
Q96MS0 BXGT025241 Roundabout homolog 3 64221 reviewed Receptor
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease