Showing entry for Acute Myeloid Leukemia (AML-M2)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD016572
Disease NameAcute Myeloid Leukemia (AML-M2)
Disease CUI IdC1879321
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O43143 BXGT004571 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 1665 reviewed Enzyme
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O95267 BXGT005368 RAS guanyl-releasing protein 1 10125 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05026 BXGT006296 Sodium/potassium-transporting ATPase subunit beta-1 481 reviewed Transporter
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07305 BXGT006594 Histone H1.0 3005 reviewed Nucleic acid binding
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07355 BXGT006609 Annexin A2 302 reviewed
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P08133 BXGT006727 Annexin A6 309 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08758 BXGT006821 Annexin A5 308 reviewed
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09525 BXGT006901 Annexin A4 307 reviewed
P09668 BXGT006914 Pro-cathepsin H 1512 reviewed Enzyme
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P12830 BXGT007852 Cadherin-1 999 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P17655 BXGT008325 Calpain-2 catalytic subunit 824 reviewed Enzyme
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20591 BXGT008586 Interferon-induced GTP-binding protein Mx1 4599 reviewed Enzyme modulator
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35221 BXGT009798 Catenin alpha-1 1495 reviewed Cellular structure
P35658 BXGT009859 Nuclear pore complex protein Nup214 8021 reviewed Nucleic acid binding
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P55210 BXGT011110 Caspase-7 840 reviewed Enzyme
P60903 BXGT011339 Protein S100-A10 6281 reviewed Calcium-binding protein
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q02363 BXGT012650 DNA-binding protein inhibitor ID-2 3398 reviewed Transcription factor
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07343 BXGT012926 cAMP-specific 3',5'-cyclic phosphodiesterase 4B 5142 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q13885 BXGT013400 Tubulin beta-2A chain 7280 reviewed Cellular structure
Q13951 BXGT013407 Core-binding factor subunit beta 865 reviewed
Q14141 BXGT013447 Septin-6 23157 reviewed Enzyme modulator
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q8N8S7 BXGT018531 Protein enabled homolog 55740 reviewed
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 10919 reviewed Epigenetic regulator
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 11040 reviewed Kinase
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
P21926 BXGT024578 CD9 antigen 928 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease