Showing entry for Increased fracture rate



                               
General Disease Information
BXGD IdBXGD019481
Disease NameIncreased fracture rate
Disease CUI IdC3805574
MeSH Codes   
Disease Class Name
Semantic TypeFinding
Human Phenotype Ontology Id HP:0000924  
Human Phenotype Ontology TermAbnormality of the skeletal system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15120 BXGT004129 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 10555 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P05186 BXGT006338 Alkaline phosphatase, tissue-nonspecific isozyme 249 reviewed Enzyme
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P23284 BXGT008845 Peptidyl-prolyl cis-trans isomerase B 5479 reviewed
P32322 BXGT009624 Pyrroline-5-carboxylate reductase 1, mitochondrial 5831 reviewed
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P42702 BXGT010335 Leukemia inhibitory factor receptor 3977 reviewed Signaling
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P51795 BXGT010891 H(+)/Cl(-) exchange transporter 5 1184 reviewed Ion channel
P52788 BXGT010953 Spermine synthase 6611 reviewed
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q16828 BXGT013676 Dual specificity protein phosphatase 6 1848 reviewed
Q32P28 BXGT014324 Prolyl 3-hydroxylase 1 64175 reviewed Extracellular structure
Q6VVX0 BXGT016585 Vitamin D 25-hydroxylase 120227 reviewed
Q9BQ65 BXGT020107 U6 snRNA phosphodiesterase 79650 reviewed
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9Y5X0 BXGT022305 Sorting nexin-10 29887 reviewed
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
Q53GS7 BXGT023762 Nucleoporin GLE1 2733 reviewed Transporter
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
P51798 BXGT026083 H(+)/Cl(-) exchange transporter 7 1186 reviewed Ion channel
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease