Showing entry for Pancreatitis, Chronic


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003328
Disease NamePancreatitis, Chronic
Disease CUI IdC0149521
MeSH Codes C06  
Disease Class NameDigestive System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0025031   HP:0002715  
Human Phenotype Ontology TermAbnormality of the digestive system; Abnormality of the immune system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00330 BXGT003910 Pyruvate dehydrogenase protein X component, mitochondrial 8050 reviewed Enzyme
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O43826 BXGT004629 Glucose-6-phosphate exchanger SLC37A4 2542 reviewed Transporter
O60704 BXGT004895 Protein-tyrosine sulfotransferase 2 8459 reviewed Enzyme
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75369 BXGT005119 Filamin-B 2317 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00751 BXGT005643 Complement factor B 629 reviewed
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02655 BXGT005912 Apolipoprotein C-II 344 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P03950 BXGT006116 Angiogenin 283 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04155 BXGT006155 Trefoil factor 1 7031 reviewed Signaling
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04183 BXGT006166 Thymidine kinase, cytosolic 7083 reviewed Kinase
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07477 BXGT006629 Trypsin-1 5644 reviewed Enzyme
P07478 BXGT006630 Trypsin-2 5645 reviewed Enzyme
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09238 BXGT006875 Stromelysin-2 4319 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14625 BXGT008029 Endoplasmin 7184 reviewed Chaperone
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15085 BXGT008077 Carboxypeptidase A1 1357 reviewed Enzyme
P15086 BXGT008078 Carboxypeptidase B 1360 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P17538 BXGT008314 Chymotrypsinogen B 1504 reviewed Enzyme
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 54578 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P21452 BXGT008653 Substance-K receptor 6865 reviewed G-protein coupled receptor
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P30989 BXGT009492 Neurotensin receptor type 1 4923 reviewed G-protein coupled receptor
P32239 BXGT009612 Gastrin/cholecystokinin type B receptor 887 reviewed G-protein coupled receptor
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35030 BXGT009784 Trypsin-3 5646 reviewed Enzyme
P35052 BXGT009788 Glypican-1 2817 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48052 BXGT010612 Carboxypeptidase A2 1358 reviewed Enzyme
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P53041 BXGT010968 Serine/threonine-protein phosphatase 5 5536 reviewed
P54317 BXGT011045 Pancreatic lipase-related protein 2 5408 reviewed Enzyme
P59665 BXGT011272 Neutrophil defensin 1 728358 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P78504 BXGT011844 Protein jagged-1 182 reviewed
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P80075 BXGT011876 C-C motif chemokine 8 6355 reviewed Signaling
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q03403 BXGT012712 Trefoil factor 2 7032 reviewed Signaling
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q05516 BXGT012822 Zinc finger and BTB domain-containing protein 16 7704 reviewed Transcription factor
Q06828 BXGT012893 Fibromodulin 2331 reviewed
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q13423 BXGT013352 NAD(P) transhydrogenase, mitochondrial 23530 reviewed Enzyme
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14195 BXGT013453 Dihydropyrimidinase-related protein 3 1809 reviewed Enzyme
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q15431 BXGT013571 Synaptonemal complex protein 1 6847 reviewed
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16674 BXGT013655 Melanoma-derived growth regulatory protein 8190 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8WWM9 BXGT019001 Cytoglobin 114757 reviewed
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92918 BXGT019394 Mitogen-activated protein kinase kinase kinase kinase 1 11184 reviewed Kinase
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q99895 BXGT019974 Chymotrypsin-C 11330 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZU7 BXGT020426 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 58190 reviewed
Q9GZV3 BXGT020427 High affinity choline transporter 1 60482 reviewed Transporter
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 54577 reviewed
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 54576 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y3S1 BXGT022266 Serine/threonine-protein kinase WNK2 65268 reviewed Kinase
Q9Y5S8 BXGT022302 NADPH oxidase 1 27035 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q13007 BXGT023883 Interleukin-24 11009 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
P23511 BXGT025343 Nuclear transcription factor Y subunit alpha 4800 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease