Showing entry for Mitogen-activated protein kinase 15


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018803
Protein NameMitogen-activated protein kinase 15
Uniport IdQ8TD08
GeneMAPK15
Gene Id225689
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04657 IL-17 signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0090494 dopamine uptake
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:1905188 positive regulation of metaphase/anaphase transition of meiosis I
Biological Process GO:1905832 positive regulation of spindle assembly
Biological Process GO:0051973 positive regulation of telomerase activity
Biological Process GO:1904355 positive regulation of telomere capping
Biological Process GO:0032212 positive regulation of telomere maintenance via telomerase
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:1904491 protein localization to ciliary transition zone
Biological Process GO:0010506 regulation of autophagy
Biological Process GO:1902017 regulation of cilium assembly
Biological Process GO:0003400 regulation of COPII vesicle coating
Biological Process GO:0010468 regulation of gene expression
molecular function GO:0005524 ATP binding
molecular function GO:0003682 chromatin binding
molecular function GO:0016301 kinase activity
molecular function GO:0004707 MAP kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0017124 SH3 domain binding
cellular component GO:0005776 autophagosome
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005911 cell-cell junction
cellular component GO:0005814 centriole
cellular component GO:0036064 ciliary basal body
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005576 extracellular region
cellular component GO:0005794 Golgi apparatus
cellular component GO:0072687 meiotic spindle
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0019269 BXGD001310 Hermaphroditism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0205851 BXGD004132 Germ cell tumor Neoplasms
C0206659 BXGD004222 Embryonal Carcinoma Neoplasms
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0677898 BXGD009735 invasive cancer Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1608408 BXGD013434 Malignant transformation
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000655 Harmalol 200.24
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0007014 Harman 182.22
BXGC0024554 D-luciferin 280
BXGC0034256 Rottlerin 516.18
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0051873 Sl-0101 516.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein