acompound

Showing entry for Harman

General Compound Information
BXGC Id	BXGC0007014
Compound Name	Harman
Structure
Formula	C12H10N2
InchiKey	PSFDQSOCUJVVGF-UHFFFAOYSA-N
SMILES	CC1=C2NC3=CC=CC=C3C2=CC=N1
Inchi	InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3
IUPAC	1-methyl-9H-pyrido[3,4-b]indole
Molecular Weight	182.22
Pubchem Id	5281404
Chembl Id	CHEMBL12014

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50013786

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT004598	Bcl-2-like protein 11	reviewed		BCL2L11	-	-	-	>350000
reviewed	BXGT007595	Cytochrome P450 2D6	reviewed		CYP2D6	86000	-	-	-
reviewed	BXGT004559	Acetylcholinesterase	reviewed		ache	-	20910	-	-

CHEMBL

CHEMBL12014

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O96013	BXGT005414	Serine/threonine-protein kinase PAK 4	reviewed	Kinase	PAK4	Activity	'='	103	%
P48730	BXGT010656	Casein kinase I isoform delta	reviewed	Kinase	CSNK1D	Activity	'='	99	%
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	12589	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	'='	1258	nM
P25779	BXGT009067	Cruzipain	reviewed	-		Potency	'='	39810	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	AC50	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	AC50	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	AC50	'='	10000	nM
Q15759	BXGT013595	Mitogen-activated protein kinase 11	reviewed	Kinase	MAPK11	Activity	'='	90	%
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	35481	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	3981	nM
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Activity	'='	95	%
Q8TD08	BXGT018803	Mitogen-activated protein kinase 15	reviewed	Kinase	MAPK15	Activity	'='	70	%
P00523	BXGT005572	Proto-oncogene tyrosine-protein kinase Src	reviewed	-	SRC	Activity	'='	83	%
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	'='	630	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	19952	nM
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	IC50	'='	20910	nM
Q14012	BXGT013437	Calcium/calmodulin-dependent protein kinase type 1	reviewed	Kinase	CAMK1	Activity	'='	91	%
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	39810	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	39810	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	99	%
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	reviewed	-	PTPN1	Inhibition	'='	7	%
P27448	BXGT009183	MAP/microtubule affinity-regulating kinase 3	reviewed	Kinase	MARK3	Activity	'='	128	%
Q15418	BXGT013569	Ribosomal protein S6 kinase alpha-1	reviewed	Kinase	RPS6KA1	Activity	'='	98	%
Q9H422	BXGT020469	Homeodomain-interacting protein kinase 3	reviewed	Kinase	HIPK3	Activity	'='	104	%
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	-	-	-
Q9BUB5	BXGT020133	MAP kinase-interacting serine/threonine-protein kinase 1	reviewed	Kinase	MKNK1	Activity	'='	82	%
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	reviewed	Kinase	IKBKB	Activity	'='	76	%
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	Activity	'='	74	%
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	reviewed	Kinase	RPS6KA3	Activity	'='	94	%
Q96SB4	BXGT019740	SRSF protein kinase 1	reviewed	Kinase	SRPK1	Activity	'='	81	%
Q9P286	BXGT021299	Serine/threonine-protein kinase PAK 5	reviewed	Kinase	PAK5	Activity	'='	97	%
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	15848	nM
Q9H2X6	BXGT020458	Homeodomain-interacting protein kinase 2	reviewed	Kinase	HIPK2	Activity	'='	104	%
Q9UQB9	BXGT021810	Aurora kinase C	reviewed	Kinase	AURKC	Activity	'='	87	%
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	9196	nM
Q96RR4	BXGT019734	Calcium/calmodulin-dependent protein kinase kinase 2	reviewed	Kinase	CAMKK2	Activity	'='	93	%
P19784	BXGT008513	Casein kinase II subunit alpha'	reviewed	Kinase	CSNK2A2	Activity	'='	85	%
P68400	BXGT011599	Casein kinase II subunit alpha	reviewed	Kinase	CSNK2A1	Activity	'='	85	%
P67870	BXGT011566	Casein kinase II subunit beta	reviewed	Kinase	CSNK2B	Activity	'='	85	%
P06240	BXGT006428	Proto-oncogene tyrosine-protein kinase LCK	reviewed	-	Lck	Activity	'='	93	%
Q9ES14	BXGT020314	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	-	Gabre	IC50	'='	12387	nM
Q91ZM7	BXGT019327	GABA theta subunit	unreviewed	-	Gabrq	IC50	'='	12387	nM
P63138	BXGT011502	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	-	Gabrb2	IC50	'='	12387	nM
P63079	BXGT011491	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	-	Gabrb3	IC50	'='	12387	nM
P62813	BXGT011460	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	-	Gabra1	IC50	'='	12387	nM
P30191	BXGT009410	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	-	Gabra6	IC50	'='	12387	nM
P28473	BXGT009261	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	-	Gabrg3	IC50	'='	12387	nM
P28471	BXGT009259	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	-	Gabra4	IC50	'='	12387	nM
P23576	BXGT008885	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	-	Gabra2	IC50	'='	12387	nM
P23574	BXGT008884	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	-	Gabrg1	IC50	'='	12387	nM
P20236	BXGT008551	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	-	Gabra3	IC50	'='	12387	nM
P19969	BXGT008536	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	-	Gabra5	IC50	'='	12387	nM
P18508	BXGT008412	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	-	Gabrg2	IC50	'='	12387	nM
P18506	BXGT008410	Gamma-aminobutyric acid receptor subunit delta	reviewed	-	Gabrd	IC50	'='	12387	nM
P15431	BXGT008122	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	-	Gabrb1	IC50	'='	12387	nM
O09028	BXGT004049	Gamma-aminobutyric acid receptor subunit pi	reviewed	-	Gabrp	IC50	'='	12387	nM
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	28183	nM
Q8IW41	BXGT018352	MAP kinase-activated protein kinase 5	reviewed	Kinase	MAPKAPK5	Activity	'='	84	%
Q16513	BXGT013632	Serine/threonine-protein kinase N2	reviewed	Kinase	PKN2	Activity	'='	85	%
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	22387	nM
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	19952	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	28183	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Potency	'='	31622	nM
Q86V86	BXGT017617	Serine/threonine-protein kinase pim-3	reviewed	-	PIM3	Activity	'='	80	%
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	Activity	'='	90	%
Q9HBH9	BXGT020521	MAP kinase-interacting serine/threonine-protein kinase 2	reviewed	Kinase	MKNK2	Activity	'='	112	%
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Potency	'='	100000	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	'='	35481	nM
P53350	BXGT010984	Serine/threonine-protein kinase PLK1	reviewed	Kinase	PLK1	Activity	'='	81	%
O96017	BXGT005415	Serine/threonine-protein kinase Chk2	reviewed	Kinase	CHEK2	Activity	'='	92	%
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Ki	'='	86000	nM
Q9ES14	BXGT020314	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	-	Gabre	IC50	'='	12400	nM
Q91ZM7	BXGT019327	GABA theta subunit	unreviewed	-	Gabrq	IC50	'='	12400	nM
P63138	BXGT011502	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	-	Gabrb2	IC50	'='	12400	nM
P63079	BXGT011491	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	-	Gabrb3	IC50	'='	12400	nM
P62813	BXGT011460	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	-	Gabra1	IC50	'='	12400	nM
P30191	BXGT009410	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	-	Gabra6	IC50	'='	12400	nM
P28473	BXGT009261	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	-	Gabrg3	IC50	'='	12400	nM
P28471	BXGT009259	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	-	Gabra4	IC50	'='	12400	nM
P23576	BXGT008885	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	-	Gabra2	IC50	'='	12400	nM
P23574	BXGT008884	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	-	Gabrg1	IC50	'='	12400	nM
P20236	BXGT008551	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	-	Gabra3	IC50	'='	12400	nM
P19969	BXGT008536	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	-	Gabra5	IC50	'='	12400	nM
P18508	BXGT008412	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	-	Gabrg2	IC50	'='	12400	nM
P18506	BXGT008410	Gamma-aminobutyric acid receptor subunit delta	reviewed	-	Gabrd	IC50	'='	12400	nM
P15431	BXGT008122	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	-	Gabrb1	IC50	'='	12400	nM
O09028	BXGT004049	Gamma-aminobutyric acid receptor subunit pi	reviewed	-	Gabrp	IC50	'='	12400	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	28183	nM
Q9P1W9	BXGT021296	Serine/threonine-protein kinase pim-2	reviewed	Kinase	PIM2	Activity	'='	85	%
P28593	BXGT009278	Trypanothione reductase	reviewed	-	TPR	Inhibition	'='	10	%
Q92630	BXGT019360	Dual specificity tyrosine-phosphorylation-regulated kinase 2	reviewed	Kinase	DYRK2	Activity	'='	83	%
Q8TDX7	BXGT018817	Serine/threonine-protein kinase Nek7	reviewed	Kinase	NEK7	Activity	'='	105	%
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	25118	nM
O14757	BXGT004092	Serine/threonine-protein kinase Chk1	reviewed	Kinase	CHEK1	Activity	'='	99	%
Q16644	BXGT013647	MAP kinase-activated protein kinase 3	reviewed	Kinase	MAPKAPK3	Activity	'='	104	%
Q9HC98	BXGT020528	Serine/threonine-protein kinase Nek6	reviewed	Kinase	NEK6	Activity	'='	90	%
Q13188	BXGT013324	Serine/threonine-protein kinase 3	reviewed	Kinase	STK3	Activity	'='	81	%
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	reviewed	Kinase	PIM1	Activity	'='	94	%
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	Activity	'='	107	%
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	31622	nM
O75116	BXGT005100	Rho-associated protein kinase 2	reviewed	Kinase	ROCK2	Activity	'='	104	%
O15530	BXGT004177	3-phosphoinositide-dependent protein kinase 1	reviewed	Kinase	PDPK1	Activity	'='	90	%
P53778	BXGT011013	Mitogen-activated protein kinase 12	reviewed	Kinase	MAPK12	Activity	'='	97	%
Q92698	BXGT019362	DNA repair and recombination protein RAD54-like	reviewed	-	RAD54L	AC50	-	58370	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Potency	'='	10000	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	31622	nM
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	reviewed	Transcription factor	NFKB1	Potency	'='	1995	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	25929	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	25118	nM
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	reviewed	Kinase	AKT1	Activity	'='	104	%
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	reviewed	Kinase	MAP2K1	Activity	'='	90	%
O00418	BXGT003918	Eukaryotic elongation factor 2 kinase	reviewed	Kinase	EEF2K	Activity	'='	101	%
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	reviewed	Kinase	DYRK1A	Activity	'='	44	%
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	31622	nM
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	reviewed	Kinase	NEK2	Activity	'='	79	%
Q05513	BXGT012820	Protein kinase C zeta type	reviewed	Kinase	PRKCZ	Activity	'='	89	%
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	56234	nM
O43781	BXGT004625	Dual specificity tyrosine-phosphorylation-regulated kinase 3	reviewed	Kinase	DYRK3	Activity	'='	72	%
P24941	BXGT009002	Cyclin-dependent kinase 2	reviewed	Kinase	CDK2	Inhibition	'='	47	%
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	reviewed	Kinase	MYLK	Activity	'='	100	%
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	39810	nM
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	39810	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	81	%
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	100000	nM
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	reviewed	Kinase	AKT2	Activity	'='	91	%
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	Ion channel	GABRA6	IC50	'='	12302	nM
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	Ion channel	GABRA5	IC50	'='	12302	nM
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	Ion channel	GABRA2	IC50	'='	12302	nM
P78334	BXGT011834	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	Ion channel	GABRE	IC50	'='	12302	nM
P18505	BXGT008409	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	Ion channel	GABRB1	IC50	'='	12302	nM
Q8N1C3	BXGT018498	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	Ion channel	GABRG1	IC50	'='	12302	nM
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	reviewed	Ion channel	GABRD	IC50	'='	12302	nM
O00591	BXGT003939	Gamma-aminobutyric acid receptor subunit pi	reviewed	Ion channel	GABRP	IC50	'='	12302	nM
P34903	BXGT009769	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	Ion channel	GABRA3	IC50	'='	12302	nM
Q9UN88	BXGT021783	Gamma-aminobutyric acid receptor subunit theta	reviewed	Ion channel	GABRQ	IC50	'='	12302	nM
Q99928	BXGT019975	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	Ion channel	GABRG3	IC50	'='	12302	nM
P48169	BXGT010622	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	Ion channel	GABRA4	IC50	'='	12302	nM
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	Ion channel	GABRB3	IC50	'='	12302	nM
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	Ion channel	GABRG2	IC50	'='	12302	nM
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	Ion channel	GABRB2	IC50	'='	12302	nM
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	Ion channel	GABRA1	IC50	'='	12302	nM
Q9ES14	BXGT020314	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	-	Gabre	Ki	'='	12400	nM
Q91ZM7	BXGT019327	GABA theta subunit	unreviewed	-	Gabrq	Ki	'='	12400	nM
P63138	BXGT011502	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	-	Gabrb2	Ki	'='	12400	nM
P63079	BXGT011491	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	-	Gabrb3	Ki	'='	12400	nM
P62813	BXGT011460	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	-	Gabra1	Ki	'='	12400	nM
P30191	BXGT009410	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	-	Gabra6	Ki	'='	12400	nM
P28473	BXGT009261	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	-	Gabrg3	Ki	'='	12400	nM
P28471	BXGT009259	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	-	Gabra4	Ki	'='	12400	nM
P23576	BXGT008885	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	-	Gabra2	Ki	'='	12400	nM
P23574	BXGT008884	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	-	Gabrg1	Ki	'='	12400	nM
P20236	BXGT008551	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	-	Gabra3	Ki	'='	12400	nM
P19969	BXGT008536	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	-	Gabra5	Ki	'='	12400	nM
P18508	BXGT008412	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	-	Gabrg2	Ki	'='	12400	nM
P18506	BXGT008410	Gamma-aminobutyric acid receptor subunit delta	reviewed	-	Gabrd	Ki	'='	12400	nM
P15431	BXGT008122	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	-	Gabrb1	Ki	'='	12400	nM
O09028	BXGT004049	Gamma-aminobutyric acid receptor subunit pi	reviewed	-	Gabrp	Ki	'='	12400	nM
P45983	BXGT010494	Mitogen-activated protein kinase 8	reviewed	Kinase	MAPK8	Activity	'='	92	%
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	21192	nM
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	reviewed	Kinase	CDK5	Inhibition	'='	65	%
Q6W5P4	BXGT016588	Neuropeptide S receptor	reviewed	-	NPSR1	Potency	'='	5011	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	28183	nM
Q8IWQ3	BXGT018355	Serine/threonine-protein kinase BRSK2	reviewed	Kinase	BRSK2	Activity	'='	101	%
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	'='	3981	nM
O75582	BXGT005137	Ribosomal protein S6 kinase alpha-5	reviewed	Kinase	RPS6KA5	Activity	'='	91	%
Q9NQU5	BXGT021169	Serine/threonine-protein kinase PAK 6	reviewed	-	PAK6	Activity	'='	105	%
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	11220	nM
P17612	BXGT008322	cAMP-dependent protein kinase catalytic subunit alpha	reviewed	Kinase	PRKACA	Activity	'='	95	%
P78396	BXGT011842	Cyclin-A1	reviewed	Enzyme modulator	CCNA1	Activity	'='	103	%
P20248	BXGT008554	Cyclin-A2	reviewed	Enzyme modulator	CCNA2	Activity	'='	103	%
P24941	BXGT009002	Cyclin-dependent kinase 2	reviewed	Kinase	CDK2	Activity	'='	103	%
Q96GD4	BXGT019667	Aurora kinase B	reviewed	Kinase	AURKB	Activity	'='	106	%
P53779	BXGT011014	Mitogen-activated protein kinase 10	reviewed	Kinase	MAPK10	Activity	'='	89	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Potency	'='	25118	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	22387	nM
Q15139	BXGT013546	Serine/threonine-protein kinase D1	reviewed	Kinase	PRKD1	Activity	'='	88	%
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	31622	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	100000	nM
P45984	BXGT010495	Mitogen-activated protein kinase 9	reviewed	Kinase	MAPK9	Activity	'='	84	%
O15296	BXGT004148	Arachidonate 15-lipoxygenase B	reviewed	Enzyme	ALOX15B	Potency	-	15848	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	7943	nM
O15264	BXGT004144	Mitogen-activated protein kinase 13	reviewed	Kinase	MAPK13	Activity	'='	90	%
P54132	BXGT011032	Bloom syndrome protein	reviewed	-	BLM	Potency	'='	19952	nM
P49841	BXGT010750	Glycogen synthase kinase-3 beta	reviewed	Kinase	GSK3B	Activity	'='	108	%
P41240	BXGT010242	Tyrosine-protein kinase CSK	reviewed	Kinase	CSK	Activity	'='	81	%
P49137	BXGT010680	MAP kinase-activated protein kinase 2	reviewed	Kinase	MAPKAPK2	Activity	'='	109	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	23715	nM
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	IC50	-	-	-
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	15003	nM
Q25615	BXGT013900	Chitinase	unreviewed	-		IC50	'='	7330	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	31622	nM
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	Inhibition	'='	43	%
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	22387	nM
P23443	BXGT008866	Ribosomal protein S6 kinase beta-1	reviewed	Kinase	RPS6KB1	Activity	'='	94	%
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	reviewed	Kinase	SGK1	Activity	'='	86	%
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	7079	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Potency	'='	1995	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	25118	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	11220	nM
P25779	BXGT009067	Cruzipain	reviewed	-		Potency	'='	25118	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	79432	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	562	nM
Q8N5S9	BXGT018520	Calcium/calmodulin-dependent protein kinase kinase 1	reviewed	Kinase	CAMKK1	Activity	'='	86	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	26608	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	44668	nM
O15648	BXGT004185	ATP-dependent 6-phosphofructokinase	reviewed	-	pfk	Potency	-	756	nM
Q14680	BXGT013499	Maternal embryonic leucine zipper kinase	reviewed	Kinase	MELK	Activity	'='	82	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	14963	nM
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	83	%
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	20596	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00040	Pepper (C. annuum)	Capsicum annuum	Vegetables
BXGF00049	Chicory	Cichorium intybus	Vegetables
BXGF00063	Saffron	Crocus sativus	Herbs and Spices
BXGF00087	Sea-buckthornberry	Hippophae rhamnoides	Fruits
BXGF00128	Passion fruit	Passiflora edulis	Fruits
BXGF00823	Fruits		Fruits
BXGF00915	Ophiorrhiza liukiuensis	Ophiorrhiza liukiuensis	Medicinal Plant
BXGF00956	Passiflora incarnata	Passiflora incarnata	Medicinal Plant
BXGF01008	Peganum harmala	Peganum harmala	Medicinal Plant
BXGF01654	Plumbago zeylanica	Plumbago zeylanica	Medicinal Plant
BXGF01767	Uncaria rhynchophylla	Uncaria rhynchophylla	Medicinal Plant
BXGF02256	Rumex chalepensis	Rumex chalepensis	Others
BXGF02745	Rauvolfia verticillata	Rauvolfia verticillata	Medicinal Plant
BXGF04000	Viola philippica	Viola philippica	Others
BXGF04400	Polygala tenuifolia	Polygala tenuifolia	Medicinal Plant
BXGF04966	Symplocos setchuensis	Symplocos setchuensis	Others
BXGF05158	Elaeagnus angustifolia	Elaeagnus angustifolia	Medicinal Plant
BXGF05335	Uncaria elliptica	Uncaria elliptica	Medicinal Plant
BXGF05837	Tribulus terrestris	Tribulus terrestris	Medicinal Plant
BXGF05936	Commelina communis	Commelina communis	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}