adisease

Showing entry for invasive cancer

General Disease Information
BXGD Id	BXGD009735
Disease Name	invasive cancer
Disease CUI Id	C0677898
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00187	BXGT003890	Mannan-binding lectin serine protease 2	10747	reviewed	Enzyme
O00330	BXGT003910	Pyruvate dehydrogenase protein X component, mitochondrial	8050	reviewed	Enzyme
O14684	BXGT004082	Prostaglandin E synthase	9536	reviewed
O14965	BXGT004117	Aurora kinase A	6790	reviewed	Kinase
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11217	BXGT007674	Glycogen phosphorylase, muscle form	5837	reviewed	Enzyme
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P22223	BXGT008744	Cadherin-3	1001	reviewed
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22455	BXGT008772	Fibroblast growth factor receptor 4	2264	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P29372	BXGT009336	DNA-3-methyladenine glycosylase	4350	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35408	BXGT009828	Prostaglandin E2 receptor EP4 subtype	5734	reviewed	G-protein coupled receptor
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48740	BXGT010659	Mannan-binding lectin serine protease 1	5648	reviewed	Enzyme
P49116	BXGT010678	Nuclear receptor subfamily 2 group C member 2	7182	reviewed	Nuclear receptor
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62826	BXGT011463	GTP-binding nuclear protein Ran	5901	reviewed	Enzyme modulator
P68104	BXGT011575	Elongation factor 1-alpha 1	1915	reviewed	Enzyme
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q12797	BXGT013266	Aspartyl/asparaginyl beta-hydroxylase	444	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15465	BXGT013573	Sonic hedgehog protein	6469	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q8TD08	BXGT018803	Mitogen-activated protein kinase 15	225689	reviewed	Kinase
Q92736	BXGT019367	Ryanodine receptor 2	6262	reviewed	Ion channel
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q96GD0	BXGT019665	Pyridoxal phosphate phosphatase	57026	reviewed	Enzyme
Q96T88	BXGT019747	E3 ubiquitin-protein ligase UHRF1	29128	reviewed
Q9NYY3	BXGT021264	Serine/threonine-protein kinase PLK2	10769	reviewed	Kinase
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y2M0	BXGT022241	Fanconi-associated nuclease 1	22909	reviewed
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P98082	BXGT025047	Disabled homolog 2	1601	reviewed	Signaling
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
Q9P2E7	BXGT025815	Protocadherin-10	57575	reviewed
P33993	BXGT025970	DNA replication licensing factor MCM7	4176	reviewed	Enzyme
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}