Showing entry for Multidrug and toxin extrusion protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019660
Protein NameMultidrug and toxin extrusion protein 1
Uniport IdQ96FL8
GeneSLC47A1
Gene Id55244
DomainMatE
Pfam PF01554  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0089718 amino acid import across plasma membrane
Biological Process GO:1902475 L-alpha-amino acid transmembrane transport
Biological Process GO:0097638 L-arginine import across plasma membrane
Biological Process GO:0015695 organic cation transport
Biological Process GO:0055085 transmembrane transport
Biological Process GO:0042908 xenobiotic transport
molecular function GO:0042887 amide transmembrane transporter activity
molecular function GO:0015297 antiporter activity
molecular function GO:0015179 L-amino acid transmembrane transporter activity
molecular function GO:0061459 L-arginine transmembrane transporter activity
molecular function GO:0022857 transmembrane transporter activity
molecular function GO:0042910 xenobiotic transmembrane transporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017654 BXGD001136 Glomerular Filtration Rate
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0200635 BXGD004041 Lymphocyte Count measurement
C0201976 BXGD004063 Creatinine measurement, serum (procedure)
C0202239 BXGD004087 Uric acid measurement (procedure)
C0220656 BXGD004312 Malignant ascites Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Neoplasms
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0427460 BXGD008616 Red cell distribution width determination
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000622 Nicotinic acid 123.11
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0003196 Aripiprazole 448.39
BXGC0003611 Latex 416.57
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0015879 Chlorhexidine 504.2
BXGC0030663 Metformin 129.1
BXGC0035201 Quinidine 324.18
BXGC0052646 Tubocurarine 609.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein