adisease

Showing entry for Chronic sinusitis

General Disease Information
BXGD Id	BXGD003324
Disease Name	Chronic sinusitis
Disease CUI Id	C0149516
MeSH Codes	C01 C08 C09
Disease Class Name	Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715 HP:0000152 HP:0000924
Human Phenotype Ontology Term	Abnormality of the immune system; Abnormality of head or neck; Abnormality of the skeletal system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01732	BXGT005782	T-cell surface glycoprotein CD8 alpha chain	925	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10153	BXGT007544	Non-secretory ribonuclease	6036	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15538	BXGT008137	Cytochrome P450 11B1, mitochondrial	1584	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16581	BXGT008245	E-selectin	6401	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28039	BXGT009224	Acyloxyacyl hydrolase	313	reviewed
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P29017	BXGT009305	T-cell surface glycoprotein CD1c	911	reviewed
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P32926	BXGT009680	Desmoglein-3	1830	reviewed	Cell adhesion
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35247	BXGT009804	Pulmonary surfactant-associated protein D	6441	reviewed	Surfactant
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P60981	BXGT011344	Destrin	11034	reviewed
P61626	BXGT011382	Lysozyme C	4069	reviewed
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P78540	BXGT011848	Arginase-2, mitochondrial	384	reviewed	Enzyme
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q05315	BXGT012811	Galectin-10	1178	reviewed	Signaling
Q08174	BXGT012963	Protocadherin-1	5097	reviewed
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q8N6P7	BXGT018524	Interleukin-22 receptor subunit alpha-1	58985	reviewed	Receptor
Q8NET8	BXGT018557	Transient receptor potential cation channel subfamily V member 3	162514	reviewed	Ion channel
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q99467	BXGT019923	CD180 antigen	4064	reviewed	Receptor
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NP55	BXGT021141	BPI fold-containing family A member 1	51297	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRP7	BXGT021192	Serine/threonine-protein kinase 36	27148	reviewed	Kinase
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	10800	reviewed	G-protein coupled receptor
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q8IYW5	BXGT023493	E3 ubiquitin-protein ligase RNF168	165918	reviewed
Q9UGM3	BXGT025543	Deleted in malignant brain tumors 1 protein	1755	reviewed	Enzyme
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}