Showing entry for Mild cognitive disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012006
Disease NameMild cognitive disorder
Disease CUI IdC1270972
MeSH Codes F03  
Disease Class NameMental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase 4593 reviewed Kinase
O15374 BXGT004157 Monocarboxylate transporter 5 9122 reviewed Transporter
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15427 BXGT004167 Monocarboxylate transporter 4 9123 reviewed Transporter
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43612 BXGT004605 Orexin 3060 reviewed
O43772 BXGT004623 Mitochondrial carnitine/acylcarnitine carrier protein 788 reviewed Transporter
O60259 BXGT004863 Kallikrein-8 11202 reviewed Enzyme
O75251 BXGT005107 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 374291 reviewed
O75473 BXGT005129 Leucine-rich repeat-containing G-protein coupled receptor 5 8549 reviewed G-protein coupled receptor
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02655 BXGT005912 Apolipoprotein C-II 344 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04156 BXGT006156 Major prion protein 5621 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04424 BXGT006214 Argininosuccinate lyase 435 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08236 BXGT006752 Beta-glucuronidase 2990 reviewed
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08697 BXGT006815 Alpha-2-antiplasmin 5345 reviewed Enzyme modulator
P08758 BXGT006821 Annexin A5 308 reviewed
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15907 BXGT008168 Beta-galactoside alpha-2,6-sialyltransferase 1 6480 reviewed
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16109 BXGT008194 P-selectin 6403 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P19021 BXGT008449 Peptidyl-glycine alpha-amidating monooxygenase 5066 reviewed Enzyme
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase 5610 reviewed Kinase
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20339 BXGT008565 Ras-related protein Rab-5A 5868 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22033 BXGT008721 Methylmalonyl-CoA mutase, mitochondrial 4594 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25325 BXGT009038 3-mercaptopyruvate sulfurtransferase 4357 reviewed Enzyme
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P29074 BXGT009313 Tyrosine-protein phosphatase non-receptor type 4 5775 reviewed
P29218 BXGT009322 Inositol monophosphatase 1 3612 reviewed Enzyme
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29372 BXGT009336 DNA-3-methyladenine glycosylase 4350 reviewed Enzyme
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P30519 BXGT009429 Heme oxygenase 2 3163 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P30989 BXGT009492 Neurotensin receptor type 1 4923 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P32019 BXGT009595 Type II inositol 1,4,5-trisphosphate 5-phosphatase 3633 reviewed Enzyme
P34130 BXGT009752 Neurotrophin-4 4909 reviewed Signaling
P35030 BXGT009784 Trypsin-3 5646 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42575 BXGT010318 Caspase-2 835 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P47870 BXGT010591 Gamma-aminobutyric acid receptor subunit beta-2 2561 reviewed Ion channel
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49810 BXGT010747 Presenilin-2 5664 reviewed Enzyme
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P51149 BXGT010835 Ras-related protein Rab-7a 7879 reviewed
P51159 BXGT010839 Ras-related protein Rab-27A 5873 reviewed
P51161 BXGT010841 Gastrotropin 2172 reviewed
P51693 BXGT010886 Amyloid-like protein 1 333 reviewed Enzyme modulator
P52803 BXGT010958 Ephrin-A5 1946 reviewed Signaling
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P56817 BXGT011200 Beta-secretase 1 23621 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P62805 BXGT011457 Histone H4 8370 reviewed
P63146 BXGT011504 Ubiquitin-conjugating enzyme E2 B 7320 reviewed
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P63279 BXGT011514 SUMO-conjugating enzyme UBC9 7329 reviewed
P78504 BXGT011844 Protein jagged-1 182 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02779 BXGT012670 Mitogen-activated protein kinase kinase kinase 10 4294 reviewed Kinase
Q03154 BXGT012698 Aminoacylase-1 95 reviewed
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14114 BXGT013441 Low-density lipoprotein receptor-related protein 8 7804 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15413 BXGT013568 Ryanodine receptor 3 6263 reviewed Ion channel
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q7Z2E3 BXGT017246 Aprataxin 54840 reviewed Nucleic acid binding
Q8TBE9 BXGT018790 N-acylneuraminate-9-phosphatase 140838 reviewed
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92993 BXGT019403 Histone acetyltransferase KAT5 10524 reviewed
Q96AC1 BXGT019617 Fermitin family homolog 2 10979 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96QV1 BXGT019722 Hedgehog-interacting protein 64399 reviewed
Q9BY08 BXGT020177 Emopamil-binding protein-like 84650 reviewed Enzyme
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9GZT4 BXGT020424 Serine racemase 63826 reviewed Enzyme
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 54210 reviewed
Q9NYY3 BXGT021264 Serine/threonine-protein kinase PLK2 10769 reviewed Kinase
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UJW3 BXGT021732 DNA (cytosine-5)-methyltransferase 3-like 29947 reviewed
Q9UKJ1 BXGT021744 Paired immunoglobulin-like type 2 receptor alpha 29992 reviewed
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha 815 reviewed Kinase
Q9Y316 BXGT022252 Protein MEMO1 51072 reviewed
Q9Y5Z0 BXGT022310 Beta-secretase 2 25825 reviewed Enzyme
Q9Y6A2 BXGT022324 Cholesterol 24-hydroxylase 10858 reviewed Enzyme
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
Q8IX03 BXGT024000 Protein KIBRA 23286 reviewed
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
P25090 BXGT025102 N-formyl peptide receptor 2 2358 reviewed G-protein coupled receptor
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
Q15818 BXGT026007 Neuronal pentraxin-1 4884 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease