Showing entry for Aurora kinase C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021810
Protein NameAurora kinase C
Uniport IdQ9UQB9
GeneAURKC
Gene Id6795
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008608 attachment of spindle microtubules to kinetochore
Biological Process GO:0051301 cell division
Biological Process GO:0016570 histone modification
Biological Process GO:0051321 meiotic cell cycle
Biological Process GO:0051256 mitotic spindle midzone assembly
Biological Process GO:0007052 mitotic spindle organization
Biological Process GO:0048599 oocyte development
Biological Process GO:0032467 positive regulation of cytokinesis
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0007283 spermatogenesis
molecular function GO:0005524 ATP binding
molecular function GO:0035174 histone serine kinase activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0004712 protein serine/threonine/tyrosine kinase activity
cellular component GO:0032133 chromosome passenger complex
cellular component GO:0000793 condensed chromosome
cellular component GO:0000780 condensed nuclear chromosome, centromeric region
cellular component GO:0005737 cytoplasm
cellular component GO:0030496 midbody
cellular component GO:0005819 spindle
cellular component GO:0005876 spindle microtubule
cellular component GO:0051233 spindle midzone
cellular component GO:0031616 spindle pole centrosome
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0403812 BXGD008312 Male Infertility with Large-Headed, Multiflagellar, Polyploid Spermatozoa Male Urogenital Diseases
C0403824 BXGD008316 Teratozoospermia Male Urogenital Diseases
C0432474 BXGD008793 Klinefelter's syndrome - male with more than two X chromosomes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0848676 BXGD010883 Subfertility, Male Male Urogenital Diseases
C0917731 BXGD011407 Male sterility Male Urogenital Diseases
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4025898 BXGD021853 Functional abnormality of male internal genitalia
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000655 Harmalol 200.24
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0007014 Harman 182.22
BXGC0012352 Chelerythrine 348.12
BXGC0034256 Rottlerin 516.18
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
BXGC0051873 Sl-0101 516.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein