Showing entry for 40S ribosomal protein S14


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT026033
Protein Name40S ribosomal protein S14
Uniport IdP62263
GeneRPS14
Gene Id6208
DomainRibosomal_S11
Pfam PF00411  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03010 Ribosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030218 erythrocyte differentiation
Biological Process GO:0030490 maturation of SSU-rRNA
Biological Process GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Biological Process GO:0000028 ribosomal small subunit assembly
Biological Process GO:0006364 rRNA processing
Biological Process GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Biological Process GO:0006412 translation
Biological Process GO:0006413 translational initiation
Biological Process GO:0019083 viral transcription
molecular function GO:0048027 mRNA 5'-UTR binding
molecular function GO:0003723 RNA binding
molecular function GO:0070181 small ribosomal subunit rRNA binding
molecular function GO:0003735 structural constituent of ribosome
molecular function GO:0045182 translation regulator activity
cellular component GO:0005829 cytosol
cellular component GO:0022627 cytosolic small ribosomal subunit
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0016020 membrane
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0014069 postsynaptic density
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156842 Eukaryotic Translation Elongation
R-HSA-156902 Peptide chain elongation
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2262752 Cellular responses to stress
R-HSA-2408522 Selenoamino acid metabolism
R-HSA-2408557 Selenocysteine synthesis
R-HSA-376176 Signaling by ROBO receptors
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-422475 Axon guidance
R-HSA-5663205 Infectious disease
R-HSA-6790901 rRNA modification in the nucleus and cytosol
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-71291 Metabolism of amino acids and derivatives
R-HSA-72312 rRNA processing
R-HSA-72312 rRNA processing
R-HSA-72613 Eukaryotic Translation Initiation
R-HSA-72649 Translation initiation complex formation
R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72737 Cap-dependent Translation Initiation
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-72766 Translation
R-HSA-72766 Translation
R-HSA-8868773 rRNA processing in the nucleus and cytosol
R-HSA-8868773 rRNA processing in the nucleus and cytosol
R-HSA-8953854 Metabolism of RNA
R-HSA-8953854 Metabolism of RNA
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-927802 Nonsense-Mediated Decay (NMD)
R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-9675108 Nervous system development
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002886 BXGD000144 Anemia, Macrocytic Hemic and Lymphatic Diseases
C0003129 BXGD000182 Anoxemia Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0023448 BXGD001649 Lymphoid leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023827 BXGD001707 liposarcoma Neoplasms
C0024667 BXGD001794 Animal Mammary Neoplasms Neoplasms; Animal Diseases
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0026499 BXGD001905 Monosomy Pathological Conditions, Signs and Symptoms
C0026985 BXGD001956 Myelodysplasia
C0026987 BXGD001957 Myelofibrosis Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0178416 BXGD004024 Hypoplastic anemia Hemic and Lymphatic Diseases
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0221278 BXGD004435 Anisocytosis
C0238644 BXGD004949 Anemia, severe Hemic and Lymphatic Diseases
C0242184 BXGD005140 Hypoxia Pathological Conditions, Signs and Symptoms
C0242387 BXGD005161 Mandibulofacial Dysostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases
C0265219 BXGD005468 Miller Dieker syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0278608 BXGD006549 Adult Liposarcoma Neoplasms
C0279984 BXGD006703 Childhood Liposarcoma Neoplasms
C0280451 BXGD006747 de novo myelodysplastic syndromes Hemic and Lymphatic Diseases
C0542035 BXGD009268 Erythroid hypoplasia
C0544886 BXGD009319 Somatic mutation
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700292 BXGD009884 Hypoxemia Pathological Conditions, Signs and Symptoms
C0740302 BXGD009975 5q-syndrome Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0836924 BXGD010864 Thrombocytosis Hemic and Lymphatic Diseases
C1257925 BXGD011814 Mammary Carcinoma, Animal Neoplasms; Animal Diseases
C1260899 BXGD011841 Anemia, Diamond-Blackfan Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1292779 BXGD012238 Myelodysplastic Syndrome with Isolated del(5q) Hemic and Lymphatic Diseases
C1458140 BXGD013134 Bleeding tendency Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1802398 BXGD013758 Chromosome 5, trisomy 5q Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1853237 BXGD015319 Isolated cases
C1855710 BXGD015534 Bone marrow hypocellularity
C1860320 BXGD015977 Bone marrow hypercellularity
C1963099 BXGD016682 Myelodysplasia, CTCAE
C2347761 BXGD017049 Childhood Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C2675059 BXGD017266 Refractory macrocytic anemia Hemic and Lymphatic Diseases
C2698117 BXGD017446 Anisocyte Measurement
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3900098 BXGD020106 Adult Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4023021 BXGD021070 Multiple lineage myelodysplasia Hemic and Lymphatic Diseases
C4023026 BXGD021072 Abnormal megakaryocyte morphology
C4023034 BXGD021078 Abnormality of bone marrow stromal cells
C4023091 BXGD021100 Abnormality of neutrophil morphology
C4025777 BXGD021785 Autosomal dominant contiguous gene syndrome
C4477095 BXGD022922 Increased lactate dehydrogenase activity
C4528176 BXGD023157 High Risk Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4531162 BXGD023199 Megakaryocyte nucleus hypolobulation
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein