Showing entry for Adult Myelodysplastic Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD020106
Disease NameAdult Myelodysplastic Syndrome
Disease CUI IdC3900098
MeSH Codes C15  
Disease Class NameHemic and Lymphatic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14727 BXGT004084 Apoptotic protease-activating factor 1 317 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15297 BXGT004149 Protein phosphatase 1D 8493 reviewed Enzyme
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15553 BXGT004181 Pyrin 4210 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75340 BXGT005112 Programmed cell death protein 6 10016 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P04279 BXGT006183 Semenogelin-1 6406 reviewed
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08174 BXGT006739 Complement decay-accelerating factor 1604 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12830 BXGT007852 Cadherin-1 999 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17174 BXGT008289 Aspartate aminotransferase, cytoplasmic 2805 reviewed
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21583 BXGT008667 Kit ligand 4254 reviewed
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22830 BXGT008809 Ferrochelatase, mitochondrial 2235 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26951 BXGT009147 Interleukin-3 receptor subunit alpha 3563 reviewed Signaling
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P35221 BXGT009798 Catenin alpha-1 1495 reviewed Cellular structure
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P35590 BXGT009854 Tyrosine-protein kinase receptor Tie-1 7075 reviewed Kinase
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46736 BXGT010538 Lys-63-specific deubiquitinase BRCC36 79184 reviewed Enzyme
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48060 BXGT010615 Glioma pathogenesis-related protein 1 11010 reviewed Immune response
P48729 BXGT010655 Casein kinase I isoform alpha 1452 reviewed Kinase
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49917 BXGT010765 DNA ligase 4 3981 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51580 BXGT010864 Thiopurine S-methyltransferase 7172 reviewed
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 3654 reviewed Kinase
P51878 BXGT010902 Caspase-5 838 reviewed Enzyme
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P54136 BXGT011033 Arginine--tRNA ligase, cytoplasmic 5917 reviewed
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61088 BXGT011358 Ubiquitin-conjugating enzyme E2 N 7334 reviewed
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P69905 BXGT011649 Hemoglobin subunit alpha 3040 reviewed
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P80404 BXGT011907 4-aminobutyrate aminotransferase, mitochondrial 18 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01081 BXGT012566 Splicing factor U2AF 35 kDa subunit 7307 reviewed
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q13105 BXGT013311 Zinc finger and BTB domain-containing protein 17 7709 reviewed
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 5058 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13206 BXGT013326 Probable ATP-dependent RNA helicase DDX10 1662 reviewed
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q8NBL1 BXGT018539 Protein O-glucosyltransferase 1 56983 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZ95 BXGT020196 Histone-lysine N-methyltransferase NSD3 54904 reviewed Epigenetic regulator
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 28996 reviewed Kinase
Q9HD36 BXGT020541 Bcl-2-like protein 10 10017 reviewed Signaling
Q9UJV9 BXGT021731 Probable ATP-dependent RNA helicase DDX41 51428 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9ULC5 BXGT021758 Long-chain-fatty-acid--CoA ligase 5 51703 reviewed Enzyme
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UPN9 BXGT021799 E3 ubiquitin-protein ligase TRIM33 51592 reviewed
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q13029 BXGT022688 PR domain zinc finger protein 2 7799 reviewed
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
P38646 BXGT024954 Stress-70 protein, mitochondrial 3313 reviewed
P98082 BXGT025047 Disabled homolog 2 1601 reviewed Signaling
Q9NRR4 BXGT025788 Ribonuclease 3 29102 reviewed Enzyme
P62263 BXGT026033 40S ribosomal protein S14 6208 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease