Showing entry for Taurine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0002374
Compound NameTaurine
Structure
FormulaC2H7NO3S
InchiKeyXOAAWQZATWQOTB-UHFFFAOYSA-N
SMILESNCCS(O)(=O)=O
InchiInChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
IUPAC2-aminoethane-1-sulfonic acid
Molecular Weight125.15
Pubchem Id1123
Chembl IdCHEMBL239243
Targets of Information Source
DrugBank DB01956
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P37610 BXGT009999 Alpha-ketoglutarate-dependent taurine dioxygenase reviewed - tauD approved; nutraceutical -
P54965 BXGT011096 Choloylglycine hydrolase reviewed - cbh approved; nutraceutical -
P23415 BXGT008864 Glycine receptor subunit alpha-1 reviewed Ion channel GLRA1 approved; nutraceutical agonist
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B reviewed Ion channel GRIN2B approved; nutraceutical inhibitor
P23416 BXGT008865 Glycine receptor subunit alpha-2 reviewed Ion channel GLRA2 approved; nutraceutical agonist
O75311 BXGT005109 Glycine receptor subunit alpha-3 reviewed Ion channel GLRA3 approved; nutraceutical agonist
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 reviewed Ion channel GABRA1 approved; nutraceutical -
P47869 BXGT010590 Gamma-aminobutyric acid receptor subunit alpha-2 reviewed Ion channel GABRA2 approved; nutraceutical -
P34903 BXGT009769 Gamma-aminobutyric acid receptor subunit alpha-3 reviewed Ion channel GABRA3 approved; nutraceutical -
P48169 BXGT010622 Gamma-aminobutyric acid receptor subunit alpha-4 reviewed Ion channel GABRA4 approved; nutraceutical -
P31644 BXGT009557 Gamma-aminobutyric acid receptor subunit alpha-5 reviewed Ion channel GABRA5 approved; nutraceutical -
Q16445 BXGT013629 Gamma-aminobutyric acid receptor subunit alpha-6 reviewed Ion channel GABRA6 approved; nutraceutical -
P18505 BXGT008409 Gamma-aminobutyric acid receptor subunit beta-1 reviewed Ion channel GABRB1 approved; nutraceutical -
P47870 BXGT010591 Gamma-aminobutyric acid receptor subunit beta-2 reviewed Ion channel GABRB2 approved; nutraceutical -
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 reviewed Ion channel GABRB3 approved; nutraceutical -
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta reviewed Ion channel GABRD approved; nutraceutical -
P78334 BXGT011834 Gamma-aminobutyric acid receptor subunit epsilon reviewed Ion channel GABRE approved; nutraceutical -
Q8N1C3 BXGT018498 Gamma-aminobutyric acid receptor subunit gamma-1 reviewed Ion channel GABRG1 approved; nutraceutical -
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 reviewed Ion channel GABRG2 approved; nutraceutical -
Q99928 BXGT019975 Gamma-aminobutyric acid receptor subunit gamma-3 reviewed Ion channel GABRG3 approved; nutraceutical -
O00591 BXGT003939 Gamma-aminobutyric acid receptor subunit pi reviewed Ion channel GABRP approved; nutraceutical -
Q9UN88 BXGT021783 Gamma-aminobutyric acid receptor subunit theta reviewed Ion channel GABRQ approved; nutraceutical agonist
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 reviewed G-protein coupled receptor GABBR1 approved; nutraceutical agonist
PDB TAU
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P37610 BXGT009999 Alpha-ketoglutarate-dependent taurine dioxygenase reviewed tauD - - - - -
P54965 BXGT011096 Choloylglycine hydrolase reviewed cbh - - - - -
P0A7I7 BXGT007117 GTP cyclohydrolase-2 reviewed ribA - - - - -
C3W5S1 BXGT002459 Hemagglutinin unreviewed HA - - - - -
Q6MHT0 BXGT016365 D-alanyl-D-alanine carboxypeptidase unreviewed Bd3459 - - - - -
P0AD64 BXGT007277 Beta-lactamase SHV-1 reviewed bla - - - - -
Q54727 BXGT015045 Sialidase B reviewed nanB - - - - -
P21951 BXGT008710 DNA polymerase epsilon catalytic subunit A reviewed POL2 - - - - -
Q9KL26 BXGT020939 Methyl-accepting chemotaxis protein unreviewed VC_A0923 - - - 3200 -
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 reviewed HINT1 Enzyme - - - -
Q47537 BXGT025596 Taurine-binding periplasmic protein reviewed tauA - - - - -
Binding DB 50357220
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 7800000 - - -
CHEMBL CHEMBL239243
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 39810 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 266 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 39810 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 12 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
Q7Z2H8 BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 pKi '=' 0 mM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI IC50 '>' 100 ug.mL-1
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 35481 nM
P19145 BXGT008463 General amino-acid permease GAP1 reviewed - GAP1 Inhibition '<' 15 %
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 106 nM
P25779 BXGT009067 Cruzipain reviewed - Potency '=' 39810 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 44668 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Potency '=' 39810 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 891 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 22387 nM
P15289 BXGT008102 Arylsulfatase A reviewed Enzyme ARSA Potency - 10 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 - - -
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 20596 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
P54803 BXGT011082 Galactocerebrosidase reviewed - GALC Potency - 562 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 10590 nM
Q7Z2H8 BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 Ki '=' 7800000 nM
Q9R1A7 BXGT021413 Nuclear receptor subfamily 1 group I member 2 reviewed - Nr1i2 Potency - 25118 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 7079 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00006 Garden onion Allium cepa Vegetables
BXGF00013 Dill Anethum graveolens Herbs and Spices
BXGF00022 Oat Avena sativa Cereals and cereal products
BXGF00034 Broccoli Brassica oleracea var. italica Vegetables
BXGF00036 Turnip Brassica rapa var. rapa Herbs and Spices
BXGF00065 Cucumber Cucumis sativus Gourds
BXGF00088 Barley Hordeum vulgare Cereals and cereal products
BXGF00129 Parsnip Pastinaca sativa Vegetables
BXGF00131 Parsley Petroselinum crispum Herbs and Spices
BXGF00169 Rye Secale cereale Cereals and cereal products
BXGF00174 Eggplant Solanum melongena Vegetables
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF00178 Spinach Spinacia oleracea Vegetables
BXGF00225 Swiss chard Beta vulgaris ssp. cicla Vegetables
BXGF00230 Carrot Daucus carota ssp. sativus Vegetables
BXGF00246 Red beetroot Beta vulgaris var. rubra Vegetables
BXGF00349 Irish moss Chondrus crispus Aquatic foods
BXGF00506 Shiitake Lentinus edodes Vegetables
BXGF00519 Wheat Triticum Cereals and cereal products
BXGF00787 Yellow pond-lily Nuphar lutea Herbs and Spices
BXGF00802 Soft-necked garlic Allium sativum L. var. sativum Herbs and Spices
BXGF00826 Sunburst squash (pattypan squash) Cucurbita pepo var. clypeata Gourds
BXGF00827 Green zucchini Cucurbita pepo var. cylindrica Gourds
BXGF00828 Yellow zucchini Cucurbita pepo var. cylindrica Gourds
BXGF00829 Green bell pepper Capsicum annuum Vegetables
BXGF00830 Yellow bell pepper Capsicum annuum Vegetables
BXGF00831 Orange bell pepper Capsicum annuum Vegetables
BXGF00832 Red bell pepper Capsicum annuum Vegetables
BXGF00834 Yellow wax bean Phaseolus vulgaris Pulses
BXGF00835 Green bean Phaseolus vulgaris Pulses
BXGF00836 Saskatoon berry Amelanchier alnifolia Fruits
BXGF00837 Nanking cherry Prunus tomentosa Fruits
BXGF00838 Japanese pumpkin Cucurbita maxima Gourds
BXGF00839 White cabbage Brassica oleracea L. var. capitata L. f. alba DC. Vegetables
BXGF00840 Romaine lettuce Lactuca sativa L. var. longifolia Vegetables
BXGF01199 Shuteria involucrata var. vestita Shuteria involucrata var. vestita Others
BXGF01275 Euphorbia kamerunica Euphorbia kamerunica Medicinal Plant
BXGF01573 Eria foetida Eria foetida Others
BXGF01816 Agave aurea Agave aurea Others
BXGF01988 Encephalartos altensteinii Encephalartos altensteinii Human Edible Plant
BXGF02172 Cupressus lawsoniana Cupressus lawsoniana Others
BXGF02264 Crinum erubescens Crinum erubescens Others
BXGF02374 Pentzia incana Pentzia incana Others
BXGF02429 Kobresia nepalensis Kobresia nepalensis Medicinal Plant
BXGF02486 Pronephrium triphyllum Pronephrium triphyllum Others
BXGF02567 Lycium chinense Lycium chinense Medicinal Plant
BXGF02622 Excoecaria oppositifolia Excoecaria oppositifolia Human Edible Plant
BXGF02722 Grindelia acutifolia Grindelia acutifolia Others
BXGF02809 Prangos pabularia Prangos pabularia Medicinal Plant
BXGF02893 Trifolium subterraneum Trifolium subterraneum Medicinal Plant
BXGF02923 Euphorbia marginata Euphorbia marginata Medicinal Plant
BXGF02972 Emilia sonchifolia Emilia sonchifolia Medicinal Plant
BXGF02990 Crataegus davisii Crataegus davisii Others
BXGF03002 Gardenia collinsae Gardenia collinsae Others
BXGF03041 Callistemon viminalis Callistemon viminalis Others
BXGF03061 Pausinystalia mayumbensis Pausinystalia mayumbensis Others
BXGF03074 Ajuga spectabilis Ajuga spectabilis Others
BXGF03098 Cissus pallidiflorus Cissus pallidiflorus Others
BXGF03112 Ursinia abrotanifolia Ursinia abrotanifolia Others
BXGF03123 Selliguea feei Selliguea feei Others
BXGF03133 Jungermannia hyalina Jungermannia hyalina Others
BXGF03155 Melampodium heterophyllum Melampodium heterophyllum Others
BXGF03165 Simaba multiflora Simaba multiflora Others
BXGF03181 Baphia nitida Baphia nitida Medicinal Plant
BXGF03191 Litsea pulchella Litsea pulchella Others
BXGF03214 Astragalus tragacantha Astragalus tragacantha Others
BXGF03228 Teucrium oxylepis Teucrium oxylepis Others
BXGF03248 Ligularia muliensis Ligularia muliensis Others
BXGF03261 Alstroemeria revoluta Alstroemeria revoluta Medicinal Plant
BXGF03278 Marrubium alysson Marrubium alysson Others
BXGF03295 Achillea macrophylla Achillea macrophylla Others
BXGF03481 Eupatorium havanense Eupatorium havanense Others
BXGF03645 Lycium barbarum Lycium barbarum Medicinal Plant
BXGF04318 Litsea aciculata Litsea aciculata Others
BXGF04370 Monochaetum vulcanicum Monochaetum vulcanicum Others
BXGF04477 Artemisia vestita Artemisia vestita Medicinal Plant
BXGF04683 Gymnosporia senegalensis Gymnosporia senegalensis Medicinal Plant
BXGF05150 Stevia chamaedrys Stevia chamaedrys Others
BXGF06073 Trillium camschatcense Trillium camschatcense Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease