Showing entry for 4-hydroxy-5-nitrophenyl acetic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0012706
Compound Name4-hydroxy-5-nitrophenyl acetic acid
Structure
FormulaC8H7NO5
InchiKeyQBHBHOSRLDPIHG-UHFFFAOYSA-N
SMILESOC(=O)Cc1ccc(c(c1)N(=O)=O)O
InchiInChI=1S/C8H7NO5/c10-7-2-1-5(4-8(11)12)3-6(7)9(13)14/h1-3,10H,4H2,(H,11,12)
IUPAC
Molecular Weight197.03
Pubchem Id447364
Chembl IdCHEMBL501822
Targets of Information Source
DrugBank DB08294
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P23083 BXGT008829 Immunoglobulin heavy variable 1-2 reviewed - IGHV1-2 experimental -
P01857 BXGT005796 Immunoglobulin heavy constant gamma 1 reviewed - IGHG1 experimental -
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL501822
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q16566 BXGT013639 Calcium/calmodulin-dependent protein kinase type IV reviewed Kinase CAMK4 Thermal melting change '=' 3 degrees C
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Thermal melting change '=' 0 degrees C
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Thermal melting change '=' 0 degrees C
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Thermal melting change '=' 0 degrees C
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Thermal melting change '=' 1 degrees C
O00506 BXGT003932 Serine/threonine-protein kinase 25 reviewed Kinase STK25 Thermal melting change - - -
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Thermal melting change '=' 0 degrees C
Q96NX5 BXGT019702 Calcium/calmodulin-dependent protein kinase type 1G reviewed Kinase CAMK1G Thermal melting change '=' 0 degrees C
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Thermal melting change '=' 0 degrees C
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Thermal melting change '=' 0 degrees C
Q00532 BXGT012532 Cyclin-dependent kinase-like 1 reviewed Kinase CDKL1 Thermal melting change '=' 1 degrees C
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Thermal melting change '=' 1 degrees C
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 Thermal melting change '=' 0 degrees C
Q9BVS4 BXGT020147 Serine/threonine-protein kinase RIO2 reviewed Kinase RIOK2 Thermal melting change '=' 0 degrees C
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 Thermal melting change '=' 0 degrees C
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 Thermal melting change '=' 0 degrees C
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Thermal melting change '=' 0 degrees C
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase reviewed Kinase TNIK Thermal melting change '=' 0 degrees C
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Thermal melting change '=' 0 degrees C
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Thermal melting change '=' 0 degrees C
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Thermal melting change '=' 0 degrees C
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Thermal melting change '=' 0 degrees C
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Thermal melting change '=' 0 degrees C
Q16659 BXGT013652 Mitogen-activated protein kinase 6 reviewed Kinase MAPK6 Thermal melting change '=' 0 degrees C
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Thermal melting change '=' 0 degrees C
P49759 BXGT010734 Dual specificity protein kinase CLK1 reviewed Kinase CLK1 Thermal melting change '=' 0 degrees C
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK Thermal melting change '=' 0 degrees C
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Thermal melting change '=' 0 degrees C
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Thermal melting change '=' 0 degrees C
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Thermal melting change '=' 0 degrees C
O75716 BXGT005147 Serine/threonine-protein kinase 16 reviewed Kinase STK16 Thermal melting change '=' 0 degrees C
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha reviewed Kinase CAMK2A Thermal melting change '=' 1 degrees C
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 reviewed Kinase MAP2K2 Thermal melting change '=' 0 degrees C
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Thermal melting change '=' 0 degrees C
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Thermal melting change '=' 1 degrees C
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Thermal melting change '=' 0 degrees C
Q86Y07 BXGT017631 Serine/threonine-protein kinase VRK2 reviewed Kinase VRK2 Thermal melting change '=' 0 degrees C
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Thermal melting change '=' 0 degrees C
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Thermal melting change '=' 1 degrees C
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Thermal melting change '=' 0 degrees C
Q8IV63 BXGT018341 Inactive serine/threonine-protein kinase VRK3 reviewed Kinase VRK3 Thermal melting change '=' 0 degrees C
Q09013 BXGT013023 Myotonin-protein kinase reviewed Kinase DMPK Thermal melting change '=' 1 degrees C
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Thermal melting change '=' 0 degrees C
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Thermal melting change '=' 0 degrees C
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Thermal melting change '=' 0 degrees C
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Thermal melting change '=' 0 degrees C
Q99986 BXGT019980 Serine/threonine-protein kinase VRK1 reviewed Kinase VRK1 Thermal melting change '=' 0 degrees C
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Thermal melting change '=' 1 degrees C
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Thermal melting change '=' 0 degrees C
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Thermal melting change '=' 1 degrees C
Q00536 BXGT012535 Cyclin-dependent kinase 16 reviewed Kinase CDK16 Thermal melting change '=' -1 degrees C
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 reviewed Kinase MAP2K6 Thermal melting change '=' 0 degrees C
P49761 BXGT010736 Dual specificity protein kinase CLK3 reviewed Kinase CLK3 Thermal melting change '=' 0 degrees C
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Thermal melting change '=' 0 degrees C
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Thermal melting change '=' 0 degrees C
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Thermal melting change '=' 0 degrees C
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase reviewed Kinase PBK Thermal melting change '=' 0 degrees C
Q15208 BXGT013550 Serine/threonine-protein kinase 38 reviewed Kinase STK38 Thermal melting change '=' 2 degrees C
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Thermal melting change '=' 0 degrees C
O95747 BXGT005393 Serine/threonine-protein kinase OSR1 reviewed Kinase OXSR1 Thermal melting change '=' 0 degrees C
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF04000 Viola philippica Viola philippica Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease