adisease

Showing entry for Hemophilia A

General Disease Information
BXGD Id	BXGD001277
Disease Name	Hemophilia A
Disease CUI Id	C0019069
MeSH Codes	C16 C15
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O14818	BXGT004103	Proteasome subunit alpha type-7	5688	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01903	BXGT005814	HLA class II histocompatibility antigen, DR alpha chain	3122	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02749	BXGT005941	Beta-2-glycoprotein 1	350	reviewed
P02760	BXGT005948	Protein AMBP	259	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02788	BXGT005963	Lactotransferrin	4057	reviewed	Enzyme
P03951	BXGT006117	Coagulation factor XI	2160	reviewed	Enzyme
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04156	BXGT006156	Major prion protein	5621	reviewed
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P07093	BXGT006544	Glia-derived nexin	5270	reviewed	Enzyme modulator
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07359	BXGT006612	Platelet glycoprotein Ib alpha chain	2811	reviewed	Receptor
P08236	BXGT006752	Beta-glucuronidase	2990	reviewed
P08709	BXGT006818	Coagulation factor VII	2155	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P13671	BXGT007941	Complement component C6	729	reviewed
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16109	BXGT008194	P-selectin	6403	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23280	BXGT008844	Carbonic anhydrase 6	765	reviewed
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	7433	reviewed	G-protein coupled receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P42357	BXGT010306	Histidine ammonia-lyase	3034	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P45984	BXGT010495	Mitogen-activated protein kinase 9	5601	reviewed	Kinase
P49257	BXGT010687	Protein ERGIC-53	3998	reviewed	Transporter
P49902	BXGT010758	Cytosolic purine 5'-nucleotidase	22978	reviewed	Enzyme
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P60568	BXGT011315	Interleukin-2	3558	reviewed
Q00610	BXGT012539	Clathrin heavy chain 1	1213	reviewed	Transporter
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q59FK2	BXGT015276	Selenocysteine lyase variant	51540	unreviewed
Q8N1Q1	BXGT018499	Carbonic anhydrase 13	377677	reviewed
Q8NI22	BXGT018571	Multiple coagulation factor deficiency protein 2	90411	reviewed	Transporter
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96I15	BXGT019674	Selenocysteine lyase	51540	reviewed	Enzyme
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9UK55	BXGT021738	Protein Z-dependent protease inhibitor	51156	reviewed	Enzyme modulator
Q9UNA0	BXGT021784	A disintegrin and metalloproteinase with thrombospondin motifs 5	11096	reviewed	Enzyme
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
Q9Y5Y6	BXGT022308	Suppressor of tumorigenicity 14 protein	6768	reviewed	Enzyme
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q9UKP6	BXGT024239	Urotensin-2 receptor	2837	reviewed	G-protein coupled receptor
P23511	BXGT025343	Nuclear transcription factor Y subunit alpha	4800	reviewed	Nucleic acid binding
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
Q9UIJ7	BXGT026029	GTP:AMP phosphotransferase AK3, mitochondrial	50808	reviewed	Kinase

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}