adisease

Showing entry for Moyamoya Disease

General Disease Information
BXGD Id	BXGD001914
Disease Name	Moyamoya Disease
Disease CUI Id	C0026654
MeSH Codes	C10 C14
Disease Class Name	Nervous System Diseases; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O94788	BXGT005333	Retinal dehydrogenase 2	8854	reviewed	Enzyme
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P04424	BXGT006214	Argininosuccinate lyase	435	reviewed	Enzyme
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P08865	BXGT006832	40S ribosomal protein SA	3921	reviewed	Nucleic acid binding
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10909	BXGT007630	Clusterin	1191	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P20062	BXGT008543	Transcobalamin-2	6948	reviewed
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P46736	BXGT010538	Lys-63-specific deubiquitinase BRCC36	79184	reviewed	Enzyme
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P62736	BXGT011452	Actin, aortic smooth muscle	59	reviewed	Cellular structure
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q02108	BXGT012634	Guanylate cyclase soluble subunit alpha-1	2982	reviewed
Q02809	BXGT012674	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	5351	reviewed	Enzyme
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q13873	BXGT013398	Bone morphogenetic protein receptor type-2	659	reviewed	Kinase
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q17RS7	BXGT013697	Flap endonuclease GEN homolog 1	348654	reviewed
Q5VST9	BXGT015886	Obscurin	84033	reviewed	Kinase
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q8NCM8	BXGT018548	Cytoplasmic dynein 2 heavy chain 1	79659	reviewed	Enzyme
Q8WZA2	BXGT019025	Rap guanine nucleotide exchange factor 4	11069	reviewed	Enzyme modulator
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9BZ29	BXGT020195	Dedicator of cytokinesis protein 9	23348	reviewed	Enzyme modulator
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
Q9Y4E8	BXGT022276	Ubiquitin carboxyl-terminal hydrolase 15	9958	reviewed	Enzyme
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q15583	BXGT024027	Homeobox protein TGIF1	7050	reviewed	Enzyme
Q8N122	BXGT026091	Regulatory-associated protein of mTOR	57521	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}