Showing entry for DNA ligase 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010765
Protein NameDNA ligase 4
Uniport IdP49917
GeneLIG4
Gene Id3981
DomainBRCT; DNA_ligase_A_C; DNA_ligase_A_M; DNA_ligase_A_N; DNA_ligase_IV
Pfam PF00533   PF04679   PF01068   PF04675   PF11411  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.4 Replication and repair hsa03450 Non-homologous end-joining
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007049 cell cycle
Biological Process GO:0051301 cell division
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0071479 cellular response to ionizing radiation
Biological Process GO:0071285 cellular response to lithium ion
Biological Process GO:0007417 central nervous system development
Biological Process GO:0051276 chromosome organization
Biological Process GO:0071897 DNA biosynthetic process
Biological Process GO:0006266 DNA ligation
Biological Process GO:0051102 DNA ligation involved in DNA recombination
Biological Process GO:0051103 DNA ligation involved in DNA repair
Biological Process GO:0006260 DNA replication
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0097680 double-strand break repair via classical nonhomologous end joining
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0075713 establishment of integrated proviral latency
Biological Process GO:0033152 immunoglobulin V(D)J recombination
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0045190 isotype switching
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0006297 nucleotide-excision repair, DNA gap filling
Biological Process GO:2001252 positive regulation of chromosome organization
Biological Process GO:0048146 positive regulation of fibroblast proliferation
Biological Process GO:0050769 positive regulation of neurogenesis
Biological Process GO:0002328 pro-B cell differentiation
Biological Process GO:0010332 response to gamma radiation
Biological Process GO:0010165 response to X-ray
Biological Process GO:0000012 single strand break repair
Biological Process GO:0035019 somatic stem cell population maintenance
Biological Process GO:0033077 T cell differentiation in thymus
Biological Process GO:0033153 T cell receptor V(D)J recombination
Biological Process GO:0033151 V(D)J recombination
molecular function GO:0005524 ATP binding
molecular function GO:0003677 DNA binding
molecular function GO:0003910 DNA ligase (ATP) activity
molecular function GO:0003909 DNA ligase activity
molecular function GO:0016874 ligase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0008022 protein C-terminus binding
cellular component GO:0000793 condensed chromosome
cellular component GO:0036464 cytoplasmic ribonucleoprotein granule
cellular component GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex
cellular component GO:0032807 DNA ligase IV complex
cellular component GO:0070419 nonhomologous end joining complex
cellular component GO:0000784 nuclear chromosome, telomeric region
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-162587 HIV Life Cycle
R-HSA-162592 Integration of provirus
R-HSA-162594 Early Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-1643685 Disease
R-HSA-164843 2-LTR circle formation
R-HSA-5663205 Infectious disease
R-HSA-5693532 DNA Double-Strand Break Repair
R-HSA-5693571 Nonhomologous End-Joining (NHEJ)
R-HSA-73894 DNA Repair
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001486 BXGD000056 Adenovirus Infections Infections
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0001857 BXGD000085 AIDS related complex Infections; Immune System Diseases
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002453 BXGD000117 Amenorrhea Pathological Conditions, Signs and Symptoms
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004135 BXGD000257 Ataxia Telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004368 BXGD000271 Autoimmune state
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005744 BXGD000330 Blepharophimosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005859 BXGD000342 Bloom Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0011606 BXGD000735 Exfoliative dermatitis Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0013604 BXGD000859 Edema Pathological Conditions, Signs and Symptoms
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014378 BXGD000912 Enterovirus Infections Infections
C0014457 BXGD000915 Eosinophilia Hemic and Lymphatic Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016842 BXGD001083 Congenital pectus excavatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020295 BXGD001372 Hydronephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020626 BXGD001452 Hypoparathyroidism Endocrine System Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0022602 BXGD001564 Actinic keratosis Neoplasms; Skin and Connective Tissue Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023474 BXGD001662 Leukemia, Myeloid, Chronic-Phase Neoplasms; Hemic and Lymphatic Diseases
C0023518 BXGD001677 Leukocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0023532 BXGD001685 Leukoplakia, Oral Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0024523 BXGD001781 Malabsorption Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026985 BXGD001956 Myelodysplasia
C0027092 BXGD001971 Myopia Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0030489 BXGD002230 Paraproteinemias Immune System Diseases; Hemic and Lymphatic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033774 BXGD002419 Pruritus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0034888 BXGD002492 Rectal Prolapse Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0035229 BXGD002516 Respiratory Insufficiency Respiratory Tract Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040147 BXGD002847 Thyroiditis Endocrine System Diseases
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0043119 BXGD003029 Werner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0043194 BXGD003036 Wiskott-Aldrich Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0080174 BXGD003106 Spina Bifida Occulta Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0086543 BXGD003294 Cataract Eye Diseases
C0087012 BXGD003318 Ataxia, Spinocerebellar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0151908 BXGD003502 Dry skin Skin and Connective Tissue Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0162670 BXGD003970 Mitochondrial Myopathies Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0175691 BXGD003999 Dubowitz syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0206019 BXGD004144 HIV Encephalopathy Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0206658 BXGD004221 Smooth Muscle Tumor Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0221277 BXGD004434 Atypical lymphocyte
C0221356 BXGD004448 Brachycephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239174 BXGD004969 Late tooth eruption
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0240635 BXGD005047 Byzanthine arch palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Stomatognathic Diseases
C0241165 BXGD005083 Thick skin
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262374 BXGD005230 Stricture of anus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0262985 BXGD005277 Psoriasiform eczema Skin and Connective Tissue Diseases
C0263401 BXGD005298 Cutis marmorata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Cardiovascular Diseases; Wounds and Injuries
C0265202 BXGD005461 Seckel syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0265660 BXGD005561 Syndactyly of the toes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266435 BXGD005668 Congenital hypoplasia of penis Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0267026 BXGD005727 Actinic cheilitis Stomatognathic Diseases
C0268579 BXGD005995 Propionic acidemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0270921 BXGD006133 Axonal neuropathy Nervous System Diseases
C0276548 BXGD006430 HIV encephalitis Infections; Immune System Diseases; Nervous System Diseases; Mental Disorders
C0277828 BXGD006480 Late fontanel closure
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334590 BXGD007129 Anaplastic Oligodendroglioma Neoplasms
C0342573 BXGD007508 PITUITARY DWARFISM I Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
C0343641 BXGD007636 Human papilloma virus infection Infections
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349506 BXGD007912 Photosensitivity of skin Skin and Connective Tissue Diseases
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393591 BXGD008102 AICARDI-GOUTIERES SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Nervous System Diseases
C0398791 BXGD008233 Nijmegen Breakage Syndrome Nutritional and Metabolic Diseases
C0401151 BXGD008274 Chronic diarrhea Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0423109 BXGD008470 Upward slant of palpebral fissure
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0423867 BXGD008517 Fine hair
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0424711 BXGD008541 Orbital separation diminished
C0426415 BXGD008560 Large nose
C0426848 BXGD008590 Sacral dimple Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0426891 BXGD008595 Broad thumbs
C0427515 BXGD008619 Neutrophil abnormality
C0432072 BXGD008718 Dysmorphic features
C0432103 BXGD008722 Submucous cleft of hard palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0456070 BXGD008863 Growth delay
C0494261 BXGD009023 Combined immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0541764 BXGD009259 Delayed bone age
C0544886 BXGD009319 Somatic mutation
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0557874 BXGD009444 Global developmental delay
C0575802 BXGD009521 Small hand
C0576226 BXGD009527 Short foot
C0578038 BXGD009542 Thin lips
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700216 BXGD009881 Structural Clinical Interview for DSM-III
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0850715 BXGD010907 Abnormality of blood and blood-forming tissues
C0878787 BXGD011392 Growth failure
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1260926 BXGD011844 Abnormal pigmentation
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1292778 BXGD012237 Chronic myeloproliferative disorder Neoplasms; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332225 BXGD012515 Aggressive Non-Hodgkin Lymphoma
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1336076 BXGD012828 Sporadic Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1512981 BXGD013196 Mammary Tumorigenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1836195 BXGD014094 Short toe
C1836542 BXGD014129 Depressed nasal bridge
C1837279 BXGD014217 Hypoplastic toenails
C1837463 BXGD014235 Narrow face
C1837758 BXGD014265 Bird-like facies
C1839758 BXGD014402 Narrow forehead
C1840069 BXGD014433 Sandal gap
C1842366 BXGD014512 Low anterior hairline
C1842714 BXGD014535 Desquamation of skin soon after birth
C1846574 BXGD014830 SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE, WITH AXONAL NEUROPATHY Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1847827 BXGD014891 LIG4 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Immune System Diseases
C1848673 BXGD014963 Hypoplastic feet
C1849367 BXGD015046 Nasal bridge wide
C1850049 BXGD015101 Clinodactyly of the 5th finger
C1854418 BXGD015402 Biparietal narrowing
C1855285 BXGD015483 Protruding ear
C1857042 BXGD015669 Sparse scalp hair
C1857206 BXGD015684 Sparse lateral eyebrow
C1857486 BXGD015710 Low-set, posteriorly rotated ears
C1857679 BXGD015735 Sloping forehead
C1859778 BXGD015931 Postnatal growth retardation
C1861866 BXGD016087 Aplasia/Hypoplasia of the corpus callosum
C1861869 BXGD016088 Underdeveloped supraorbital ridges
C1865370 BXGD016320 Severe combined immunodeficiency with sensitivity to ionizing radiation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C1866134 BXGD016378 Wide anterior fontanel
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1963094 BXGD016681 Dry Skin, CTCAE
C1963099 BXGD016682 Myelodysplasia, CTCAE
C1963165 BXGD016685 Malabsorption, CTCAE
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C1969799 BXGD016794 Severe Combined Immunodeficiency with Microcephaly, Growth Retardation, and Sensitivity to Ionizing Radiation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Immune System Diseases; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2347761 BXGD017049 Childhood Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C2700553 BXGD017472 Omenn Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C3179508 BXGD018554 Aplasia/Hypoplasia of the thumb Musculoskeletal Diseases
C3272841 BXGD018637 MUTYH-Associate Polyposis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3553764 BXGD019187 Joint hyperflexibility
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714745 BXGD019427 Malabsorption Digestive System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3900098 BXGD020106 Adult Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4016019 BXGD020257 DNA Ligase I Deficiency
C4021395 BXGD020625 Abnormality of the antihelix
C4021822 BXGD020807 Abnormality of female external genitalia
C4021956 BXGD020839 Aplasia/Hypoplasia of the eyebrow
C4022018 BXGD020872 Telangiectasia of the skin Cardiovascular Diseases
C4025579 BXGD021676 Large beaked nose
C4025814 BXGD021806 Abnormality of the metaphysis
C4048270 BXGD021897 Decreased antibody level in blood
C4049796 BXGD021951 Abnormality of cardiovascular system morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4082169 BXGD022084 Metatarsus Varus Musculoskeletal Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4551705 BXGD023397 Abnormality of chromosome stability
C4551936 BXGD023442 Anal Stenosis, CTCAE
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4744564 BXGD023947 Metastatic Colorectal Carcinoma Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0024261 Adenosine Phosphate 347.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein