adisease

Showing entry for Polydactyly

General Disease Information
BXGD Id	BXGD003590
Disease Name	Polydactyly
Disease CUI Id	C0152427
MeSH Codes	C16 C05
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id	HP:0040064 HP:0000924
Human Phenotype Ontology Term	Abnormality of limbs; Abnormality of the skeletal system
Disease Ontology Id	DOID:0080015
Disease Ontology Class Name	physical disorder
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00459	BXGT003924	Phosphatidylinositol 3-kinase regulatory subunit beta	5296	reviewed	Enzyme modulator
O00755	BXGT003945	Protein Wnt-7a	7476	reviewed	Signaling
O15119	BXGT004128	T-box transcription factor TBX3	6926	reviewed	Transcription factor
O43617	BXGT004607	Trafficking protein particle complex subunit 3	27095	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P08151	BXGT006731	Zinc finger protein GLI1	2735	reviewed
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P32754	BXGT009664	4-hydroxyphenylpyruvate dioxygenase	3242	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P43026	BXGT010351	Growth/differentiation factor 5	8200	reviewed	Signaling
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61978	BXGT011399	Heterogeneous nuclear ribonucleoprotein K	3190	reviewed	Enzyme
Q05516	BXGT012822	Zinc finger and BTB domain-containing protein 16	7704	reviewed	Transcription factor
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15465	BXGT013573	Sonic hedgehog protein	6469	reviewed
Q2M1P5	BXGT014129	Kinesin-like protein KIF7	374654	reviewed
Q7Z494	BXGT017254	Nephrocystin-3	27031	reviewed
Q8NCM8	BXGT018548	Cytoplasmic dynein 2 heavy chain 1	79659	reviewed	Enzyme
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q96PY6	BXGT019712	Serine/threonine-protein kinase Nek1	4750	reviewed	Kinase
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
Q99835	BXGT019969	Smoothened homolog	6608	reviewed	G-protein coupled receptor
Q9H0F7	BXGT020435	ADP-ribosylation factor-like protein 6	84100	reviewed
Q9NRR6	BXGT021193	Phosphatidylinositol polyphosphate 5-phosphatase type IV	56623	reviewed
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UHX1	BXGT021707	Poly(U)-binding-splicing factor PUF60	22827	reviewed
Q9UKV8	BXGT021752	Protein argonaute-2	27161	reviewed
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9UPZ9	BXGT021804	Serine/threonine-protein kinase ICK	22858	reviewed	Kinase
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
Q15583	BXGT024027	Homeobox protein TGIF1	7050	reviewed	Enzyme
P63167	BXGT024120	Dynein light chain 1, cytoplasmic	8655	reviewed	Cellular structure
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q9UKB1	BXGT025928	F-box/WD repeat-containing protein 11	23291	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}