Showing entry for Pelvic Organ Prolapse


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011327
Disease NamePelvic Organ Prolapse
Disease CUI IdC0877015
MeSH Codes C23  
Disease Class NamePathological Conditions, Signs and Symptoms
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0025031  
Human Phenotype Ontology TermAbnormality of the digestive system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O75390 BXGT005123 Citrate synthase, mitochondrial 1431 reviewed Enzyme
O75914 BXGT005165 Serine/threonine-protein kinase PAK 3 5063 reviewed Kinase
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95843 BXGT005401 Guanylyl cyclase-activating protein 3 9626 reviewed
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06401 BXGT006436 Progesterone receptor 5241 reviewed Nuclear receptor
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P09238 BXGT006875 Stromelysin-2 4319 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P13497 BXGT007915 Bone morphogenetic protein 1 649 reviewed
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P22460 BXGT008774 Potassium voltage-gated channel subfamily A member 5 3741 reviewed Ion channel
P23468 BXGT008870 Receptor-type tyrosine-protein phosphatase delta 5789 reviewed Enzyme
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27448 BXGT009183 MAP/microtubule affinity-regulating kinase 3 4140 reviewed Kinase
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P35030 BXGT009784 Trypsin-3 5646 reviewed Enzyme
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P41440 BXGT010261 Folate transporter 1 6573 reviewed Transporter
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42658 BXGT010327 Dipeptidyl aminopeptidase-like protein 6 1804 reviewed Enzyme
P51884 BXGT010903 Lumican 4060 reviewed
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q06520 BXGT012880 Bile salt sulfotransferase 6822 reviewed
Q06828 BXGT012893 Fibromodulin 2331 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q14494 BXGT013474 Endoplasmic reticulum membrane sensor NFE2L1 4779 reviewed Enzyme
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HBX9 BXGT020523 Relaxin receptor 1 59350 reviewed G-protein coupled receptor
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
Q9BVC4 BXGT026090 Target of rapamycin complex subunit LST8 64223 reviewed
Q96JB6 BXGT026118 Lysyl oxidase homolog 4 84171 reviewed
Q92888 BXGT026130 Rho guanine nucleotide exchange factor 1 9138 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease