Showing entry for Impaired insulin secretion


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011533
Disease NameImpaired insulin secretion
Disease CUI IdC0948379
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P08779 BXGT006824 Keratin, type I cytoskeletal 16 3868 reviewed
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P48147 BXGT010620 Prolyl endopeptidase 5550 reviewed Enzyme
P49286 BXGT010691 Melatonin receptor type 1B 4544 reviewed G-protein coupled receptor
P49336 BXGT010697 Cyclin-dependent kinase 8 1024 reviewed Kinase
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51787 BXGT010889 Potassium voltage-gated channel subfamily KQT member 1 3784 reviewed Ion channel
P55055 BXGT011101 Oxysterols receptor LXR-beta 7376 reviewed Nuclear receptor
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q92831 BXGT019380 Histone acetyltransferase KAT2B 8850 reviewed
Q96RJ0 BXGT019728 Trace amine-associated receptor 1 134864 reviewed G-protein coupled receptor
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q15878 BXGT022659 Voltage-dependent R-type calcium channel subunit alpha-1E 777 reviewed Ion channel
Q5FWF4 BXGT023211 DNA annealing helicase and endonuclease ZRANB3 84083 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease