Showing entry for Trace amine-associated receptor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019728
Protein NameTrace amine-associated receptor 1
Uniport IdQ96RJ0
GeneTAAR1
Gene Id134864
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0001594 trace-amine receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375280 Amine ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-418555 G alpha (s) signalling events
R-HSA-500792 GPCR ligand binding
R-HSA-5663205 Infectious disease
R-HSA-9658195 Leishmania infection
R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664433 Leishmania parasite growth and survival
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006370 BXGD000394 Bulimia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007370 BXGD000462 Catalepsy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007384 BXGD000463 Cataplexy Nervous System Diseases; Mental Disorders
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0017178 BXGD001102 Gastrointestinal Diseases Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027404 BXGD001984 Narcolepsy Nervous System Diseases; Mental Disorders
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0085602 BXGD003199 Polydipsia Pathological Conditions, Signs and Symptoms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0236734 BXGD004823 Caffeine related disorders
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0600427 BXGD009706 Cocaine Dependence Chemically-Induced Disorders; Mental Disorders
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0948379 BXGD011533 Impaired insulin secretion
C1301797 BXGD012299 Induced hypothermia (finding) Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1456624 BXGD013120 Methamphetamine abuse Chemically-Induced Disorders; Mental Disorders
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3888788 BXGD019984 Minimal hepatic encephalopathy
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000548 Tryptamine 160.22
BXGC0003994 2-Phenylethan-1-ol 122.16
BXGC0004757 2-Aminoacetophenone 135.16
BXGC0004760 2-Phenylethylamine 121.18
BXGC0004761 N-Methylphenethylamine 135.21
BXGC0005871 Dopamine 153.18
BXGC0013854 Histamine 111.08
BXGC0014068 Amphetamine 135.1
BXGC0043954 2-(4-Methoxyphenyl)Ethanamine 151.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein